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Reprogrammable Cell Type Depends on a Single Gene to Keep Its Identity
Date:12/1/2008

ther demonstrate that Prox1 activity is required by LECs to maintain their identity.

"The new insights offered by this research will give us a better understanding of how to convert one cell into another and the eventual use of the new therapeutic approaches in pathological conditions and tumors," Oliver said.

Other authors of this article include Nicole C. Johnson, Miriam E. Dillard and Sharon L. Frase (St. Jude); Peter Baluk and Donald M. McDonald (University of California, San Francisco); and Natasha L. Harvey (The Hanson Institute, Adelaide, Australia).

This work was supported in part by the National Institutes of Health, a Cancer Center Support Grant and ALSAC.

St. Jude Children's ResearchHospital

St. Jude Children's Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Founded by late entertainer Danny Thomas and based in Memphis, Tenn., St. Jude freely shares its discoveries with scientific and medical communities around the world. No family ever pays for treatments not covered by insurance, and families without insurance are never asked to pay. St. Jude is financially supported by ALSAC, its fundraising organization. For more information, please visit www.stjude.org.


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SOURCE St. Jude Children's Research Hospital
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