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ReportsnReports - Multitargeted Therapies: Promiscuous Drugs and Combination Therapies
Date:6/23/2011

DALLAS, June 23, 2011 /PRNewswire/ --


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Report Summary

Suites of drugs have been developed that can be used in combination to treat complex diseases that have multiple causes involving multiple targets. In addition, it has been found that many successful small-molecule drugs are promiscuous, i.e., they are single drugs that address multiple targets. This report on Multitargeted Therapies covers both these major approaches to development of multitargeted therapies. Discussed are:

  • The discovery and design of promiscuous drugs
  • The rational design of novel combination therapies designed to address multiple targets, including the uses of synthetic lethality and pathway biology
  • The emerging area of network pharmacology
  • Chemical proteomics methods designed to assess the degree of promiscuity of kinase inhibitors and to develop specifically multitargeted kinase inhibitors
  • The development
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