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Reportlinker Adds US Cystic Fibrosis Industry
Date:6/24/2010

Cystic Fibrosis Research II-13

Companies and Area of Research II-13

Gene Therapy- A Step Towards Cure II-14

PLASmin™ - The Only Investigational Drug Based on Gene Therapy II-14

Rising Concerns over Animal-Derived Drugs II-14

4. PIPELINE ANALYSIS II-15

Active Cystic Fibrosis Pipeline - A Ray of Hope II-15

Cystic Fibrosis Pipeline (As of January 2010) II-15

Gene Therapy II-15

Protein Assist/Repair Therapy: II-15

Restoration of Salt Transport Therapy: II-16

Anti-Inflammatory Agents: II-16

Anti-infective Agents: II-16

Other Developmental Drugs: II-17

5. DISEASE OVERVIEW II-18

Cystic Fibrosis - A Hereditary Disease II-18

Mutation in CFTR Gene - A Major Cause of CF II-18

DF508 - The Most Common Mutation that Affects CFTR Protein II-18

Table 2: Most Common Mutations and Worldwide Frequency

(includes corresponding Graph/Chart) II-18

Hereditary Risk of the Disease II-19

Pathophysiology of the Disease II-19

Symptoms of Cystic Fibrosis II-19

Common Symptoms in Early Childhood II-19

Common Symptoms in Grownups or Adults: II-20

Complications Associated with Cystic Fibrosis II-20

Sinus and Lung Illness II-20


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