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Reportlinker Adds Toxicology and Pharmacology
Date:11/3/2010

ies. The report gives an authoritative, detailed and clear explanation of the issues surrounding toxicology testing, its implications for the market and for the biotech and pharmaceutical industries.

Table of Contents Preface

Chapter 1: Introduction to Toxicology and its Outsourcing

Pre-Industrial Toxicology

Toxicology & the Chemical Industrial Revolution

Toxicity Testing

Toxicology Terminology

Chapter 2: Principles and Practices in Outsourcing Toxicology

Introduction

How to Outsource

Essentials of a Contract

Negotiation

Chapter 3: Outsourcing of Toxicology - A Potted History

Covance Inc

Life Science Research Inc (Huntingdon Laboratories)

Charles River

Harlan

NOTOX

Sequani

Laboratory of Pharmacology & Toxicology (LPT)

CIT

Chapter 4: Review of Selected Major CROs

Chapter 5: Summary of the Regulatory Environment

USA

Europe

Japan

Good Laboratory Practice (GLP)

GLP & Outsourcing

Chapter 6: The Preclinical Market

REACH

Preclinical CROs by Country

Rate of Formation of Toxicology CROs

Market Size Analysis

Chapter 7: The Use of Non Animal Testing in Toxicology

Introduction

Validation Organisations

Validation Studies

The Validation Process

Chapter 8: Conclusions and Future Challenges

Introduction

Technical Challenges

Genomics

Proteomics

Metabolomics

Biomarkers

Biopharmaceuticals

Political Challenges

Afterword

Appendix: Profiles of Preclinical and Toxicology CROs

Accelera (Italy)

Advinus (India)

Aptuit (USA)

Charles River (Edinburgh)

CIT (France)

Covance (USA)

Harlan (USA) (Including SafePharm (UK) and RCC (Switzerland})

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SOURCE Reportlinker
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