Navigation Links
Reportlinker Adds Threats to Avastin - Targeting the VEGF Pathway
Date:8/31/2010

otrient/Armala are all multi-kinase inhibitors and Pfizer's Torisel and Novartis' Afinitor are mTOR (kinase) inhibitors.

Looking forward...

Drugs with novel mechanisms of inhibiting angiogenesis are beginning to emerge in company pipelines. Espicom has identified 13 major projects in Phase III development, with a further 10 in Phase II. Novel agents include:

Enzastaurin: A novel agent that acts through inhibition of protein kinase C and has been found to suppress tumour growth through multiple mechanisms, such as the direct suppression of tumour cell proliferation.

Panobinostat: This pan-histone deacetylase inhibitor targets multiple oncogenic pathways, including angiogenesis.

PF-02341066: This is a selective ATP-competitive small-molecule inhibitor of both c-Met/hepatocyte growth factor receptor and anaplastic lymphoma kinase tyrosine kinases and their oncogenic variants.

With this report you will...

Understand Avastin's unique position in the oncology market

Evaluate its strengths and weaknesses relative to other VEGF-targeting products

Gain insight into the prevalence of cancers in Avastin's therapeutic window

Review the merits of 21 late-phase development prospects with Espicom's unique 5-point competitive assessment

Know the launch timeframe for up and coming products

Estimate future revenues with 5-year forecasts for more than 20 launched and late-phase products

Just some of the approaches being used by products in this report

VEGFr-1, -2 and -3 tyrosine kinase inhibitors

VEGF Trap

MET & RET inhibitors

PDGFr inhibitors

HDAC inhibitors

Questions answered by the report include...

Which other products in the pipeline mirror Avastin's therapeutic approach?

What are the extension indications Avastin is expected to secure to 2016?

In 2012, five products targeting the VEGF pathway are expected to lau
'/>"/>

SOURCE Reportlinker
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Reportlinker Adds The Outlook for Pharmaceuticals In The Middle East And North Africa To 2015
2. Reportlinker Adds Epigenetics: Current and future applications that are driving novel drug discovery
3. Reportlinker Adds Clinical Laboratory Testing Volume 1: Reagents and Instruments
4. Reportlinker Adds Portable and Transport Ventilator Market Shares, Strategies, and Forecasts, Worldwide, 2010 to 2016
5. Reportlinker Adds Pharmaceutical M&A in the Asia-Pacific Region - India and China drive regional activity but Japan still dominates high value transactions
6. Reportlinker Adds Strategic Analysis of End-user Preferences in the U.S. Stem Cell Research Tools Markets
7. Reportlinker Adds Production and Market of Xylose in China
8. Reportlinker Adds Advances in Large Scale BioManufacturing and Scale-Up Production, 2nd ED
9. Reportlinker Adds European Markets for Small Joint Reconstructive Devices 2010 (15 Countries)
10. Reportlinker Adds Japanese Market for Small Joint Reconstructive Devices 2010
11. Reportlinker Adds Effective Social Media Marketing Strategies for Pharmaceutical Market
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... Jan. 23, 2015  Now available for sale, The Armor1 ... that prevents ankle sprains by cushioning the ankle from ... securely around the outside of any shoe type and ... while still offering protection against sprains. With customers in ...
(Date:1/23/2015)... , Jan. 23, 2015  Lixte Biotechnology Holdings, Inc. (OTCQB: ... Phase I trial of Lixte,s lead compound, LB‑100, is being ... John S. Kovach , M.D., the founder and ... to be completed at a single site. Accrual of patients, ...
(Date:1/23/2015)... Jan. 23, 2015   Leatt Corporation  (OTCQB: LEAT), a ... for all forms of sports, including extreme motor sports, ... announced today that the UISP Lega Motociclismo Lombardia, an ... riders to wear a neck brace during its racing ...
Breaking Medicine Technology:The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 3
... , June 17 www.hra-pharma.com -HRA Pharma ... Committee for Reproductive Health Drugs voted 11 to 0 that the ... effective and safe for use as an emergency contraceptive. , ... The committee,s vote followed ...
... Mylan Inc. (Nasdaq: MYL ) today announced that its ... Food and Drug Administration (FDA) for its Abbreviated New Drug ... and 50 mg. The product was determined to be bioequivalent ... treatment for nervousness and tension.   , ...
Cached Medicine Technology:FDA Advisory Committee Unanimously Recommends Approval of HRA Pharma's Ulipristal Acetate for Emergency Contraception 2FDA Advisory Committee Unanimously Recommends Approval of HRA Pharma's Ulipristal Acetate for Emergency Contraception 3Mylan Receives Approval for Hydroxyzine Hydrochloride Tablets 2
(Date:1/22/2015)... (PRWEB) January 22, 2015 Thousand of ... Medical Care recalled its GranuFlo and NaturaLyte dialysis concentrates ... underway in U.S. District Court, District of Massachusetts, Bernstein ... 20th, the Court has remanded a case filed by ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Joan Lunden, ... keynote speaker at the upcoming 32nd Annual Miami ... Physicians’ Education Resource®, LLC (PER®) , shares that ... have gone undetected if she had not followed up ...
(Date:1/22/2015)... Palm City, Florida (PRWEB) January 22, 2015 ... use cold therapy machine with patented IsoTube design to treat ... has introduced the most progressive and easy to use ... help treat post-operative and sports related orthopedic and muscle injuries. ...
(Date:1/22/2015)... York, NY (PRWEB) January 22, 2015 As ... of overall health care gains momentum worldwide, Rev. Eric ... HealthCare Chaplaincy Network (HCCN), will be the keynote ... spiritual care in Israel’s public health system. , The conference, ...
(Date:1/22/2015)... Step into a macabre world where ... of Virginia. Wicked Plants, the Museum’s latest featured exhibition, ... poisonous, carnivorous and diabolical plants inside of a dilapidated, ... the biochemical, physical and neurological processes between botanicals and ...
Breaking Medicine News(10 mins):Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... MONDAY, Oct. 17 (HealthDay News) -- ,Fast speeds, lack of ... are among the reasons why thousands of American children are ... research. The findings were to be presented Monday at ... in Boston. According to the AAP, children account for ...
... By Randy Dotinga HealthDay Reporter , MONDAY, ... into fountains of four-letter words? Maybe so, says a new ... profanity-ridden shows and video games. However, the research ... swearing among kids, nor does it explain why non-aggressive cussing ...
... a home with a swimming pool are at risk of ... study abstract presented Monday, Oct. 17, at the American Academy ... three likely scenarios that precede the drowning of a very ... pool. In the study, "Patterns of Drowning in Young ...
... of Pennsylvania School of Nursing have found a link between ... are five times more likely to have autism than children ... small as about a pound, were followed for 21 years ... , one of the most remarkable of its kind. The ...
... cranial computed tomography (CT) scans in an emergency department ... children, a study by researchers at UC Davis has ... CT scans are underused in treating African-American and Hispanic ... children may receive too many CT scans -- and ...
... , SUNDAY, Oct. 16 (HealthDay News) -- Children ... with an "undesirable trait" if they believe it,s the ... study included 137 third- through eighth-grade students who were ... who were either a poor student or poor athlete, ...
Cached Medicine News:Health News:Too Many Kids Injured in ATV Crashes, Study Finds 2Health News:Profanity on TV Linked to Foul-Mouthed Kids 2Health News:Study identifies scenarios that precede at-home pool drownings of young children 2Health News:Low birthweight infants have five times rate of autism 2Health News:White children far more likely to receive CT scans than Hispanic, African-American children 2Health News:Kids Can Be Tougher on Obese Peers 2
...
... The TOPCON PD Meter, Model II, is ... accurate measurements are speedily obtained because it ... halves of the pupils, with internal reading ... well as nasal-pupillary distances. Since displacements between ...
... the future with the all-new EXAM-3000! ... efficiency, dramatically increase your patient flow ... and money. Todays demand for delegation ... the logical choice for the progressive ...
... of IMAGEnet Lite, a standard in powerful ... the Topcon TRC-NW6 or TRC-NW6S to assemble ... package. The system incorporates the latest advances ... retinal camera allowing a technician to perform ...
Medicine Products: