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Reportlinker Adds Successful Strategies for Drug Repositioning
Date:4/20/2011

iture.

The potential commercial benefits from successful repositioning of a drug are likely to be greater than those offered by simple reformulation, and offers opportunities for extended periods of market exclusivity via the granting of additional patents.

Major companies are well positioned to benefit from the successful repurposing of drugs, especially when they utilize both internal resources and external resources. The effective application of repurposing technologies should enable major companies to significantly enhance their development pipelines.

Your key questions answered

* What are the current advantages of repositioning over other lower risk approaches to drug development?

* What are the key technologies being used to identify new targets for molecules in companies' databases?

* How does drug repositioning improve the intellectual property position of companies that employ this strategy?

* What skills and platforms do specialist companies engaged in drug repositioning possess?

* How have molecules such as sildenafil and thalidomide been repositioned successfully?

TABLE OF CONTENTS

Executive Summary

Chapter 1 Introduction

Chapter 2 Lower Risk Strategies

Chapter 3 What is Repositioning?

Chapter 4 Strategic Approaches to Repositioning

Chapter 5 Successful case studies

Chapter 6 Current Efforts

Chapter 7 Specialist Companies

Chapter 8 Outlook

About the author

Disclaimer

Introduction

Summary

Introduction

The decline in approvals of novel chemical entities

The costs, and risks, of drug development

Lower Risk Strategies

Summary

Introduction

Enantiomeric switches

Active metabolites

Reformulation

Repositioning

What is Repositioning?

Summary

Overview

Commercial implications

Intellectual property
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SOURCE Reportlinker
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