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Reportlinker Adds Spinal Surgical Devices: Technologies and Global Markets
Date:9/23/2010

NEW YORK, Sept. 23 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Spinal Surgical Devices: Technologies and Global Markets

http://www.reportlinker.com/p0297996/Spinal-Surgical-Devices-Technologies-and-Global-Markets.html

THIS REPORT CONTAINS

A focus on how nonfusion products, including dynamic stabilization (or motion-preservation) devices and total disc replacement (TDR) are becoming the treatments of choice, especially for younger, more-active patients

Analysis of the global spinal devices market, with data for 2008, estimates for 2009, and projections of compound annual growth rates (CAGRs) through 2014

A breakdown of end-user markets, including hospitals, research facilities, freestanding spinal care clinics, and outpatient centers

An overview of the history and current state of medical spinal fusion and nonfusion devices

Comprehensive patent analyses.

INTRODUCTIONMost people at one point or another have experienced back pain. The pain usually lasts for only a short duration and then resolves itself with little or no medical attention. For others, however, the pain is unresolving, chronic, and severe, and may involve neurological symptoms, including radiating pain or numbness down an arm or leg. For these relatively few sufferers, surgical intervention may be necessary.

As individuals age, the effects of wear and tear on the body accumulate. This is true of the spine. Degenerative changes, not a single traumatic blow, are the cause of most cases that result in spinal surgery. These degenerative changes can be evidenced radiographically in nearly all people, although only a small percentage of these changes will produce symptomatic conditions. The world's population is aging at an unprecedented rate, and as this continues, the rate of degenerative spinal conditions is also expected to escalate.

Surgical treatment of spinal conditions has been marred in controversy. Fusion, a treatment largely abandoned by other orthopedic disciplines because of the resulting limited range of motion, is still the treatment of choice for spinal surgical intervention. Innovation in both devices and techniques in spine surgery was largely stagnant in the 1980s and early 1990s. Technological advances in both surgical approaches and spinal implants, however, are once again flourishing, making spine the fastest-growing segment of the global orthopedics market. 

This growth, although driven in part by escalating procedural volume, is also the result of excitement in emerging technologies in the non-fusion, or motion-preservation, segment. Initial euphoria has been dampened both by hardware durability issues and reimbursement challenges, but hope persists that the motion preservation market will drive future expansion in the spine industry through positive patient outcomes and economic efficiencies resulting from less-invasive surgeries. Biologics is another rapidly evolving segment of spinal orthopedics that is garnering great enthusiasm. Its growth prospects are high for making current techniques more effective and possibly altering the future landscape of spine surgery with the creation of technologies that actually regenerate spinal components.

STUDY GOALS AND OBJECTIVESThe technologies in this report—implantable spinal prosthetics and hardware—are pivotal to improving the quality of life for the tens of millions worldwide who suffer from back pain and neurological deficit resulting from common spinal conditions. Advances in these devices and their implantation techniques can improve the cost benefit of treatment of spinal conditions.

The objectives of this report are to present a comprehensive analysis of the market for these orthopedic products and forecast their commercial potential through 2015. 

This report will:Assess the prevalence of common spinal conditions and trends affecting their projected future incidence

Examine current procedure volumes and associated expenditures, as well as projected increases in demand by technique

Analyze the current market and forecast demand for implantable spinal surgical devices

Describe the regulatory framework and its effect on the introduction of new devices into the spinal market both in the U.S. and abroad

Analyze trends in patent applications and issued patents for innovations that will be altering the spinal marketplace

Examine the drivers that will affect future utilization and rate of adoption of the implants, including demographic changes, reimbursement policy, clinical considerations, and R&D 

Identify the product manufacturers that will drive innovation, their market share, and other industry players

REASONS FOR DOING THE STUDYThe world's population is aging at an unprecedented rate. Aging populations face increased rates of arthritic and degenerative conditions. This trend is particularly pronounced upon examination of the prevalence of back pain and underlying spinal conditions. 

The convergence of the following trends represents the motivation for this report:The worldwide growth of the senior population will strain the capabilities of healthcare providers and the financial resources of healthcare payers.

Patients are increasingly less likely to accept "aging pains" as they wish to maintain a more active lifestyle even with advancing age.

Obesity, which is also increasing globally, will similarly contribute to higher rates of back pain and degenerative conditions.

Advances in biologics, materials, imaging techniques, and the biomechanical understanding of the spine will enable treatment of spinal conditions with a focus on preservation of natural range of motion.

To contain costs while simultaneously facing an increased procedural volume, focus is shifting toward improving instruments and techniques to reduce the invasiveness of surgery, thereby shortening hospital stays and hastening recovery.

Increased focus is being placed on the cost benefit of surgical procedures and implants.

SCOPE OF REPORTThis report is a business analysis that has the primary purpose of examining trends in the market for spinal surgical devices, specifically arthroplasty products and implanted instrumentation hardware. The report includes sections on the following topics:

Current prevalence of common spinal problems, trend analysis, and factors influencing future incidence

Market analysis by surgical procedure, including annual incidence, trend analysis, and factors influencing future predicted surgical volume

Global demand by device and projected future trends by device category

Risk factors and other drivers that will affect the future incidence of spine surgery and related utilization of spinal surgical devices

U.S. and international regulation of spinal devices

Patent analysis

Market share and information on key device manufacturers

INTENDED AUDIENCEThis report is intended for anyone interested in better understanding the role of the rapidly growing spine segment of the broader orthopedic and biologic markets. Executives, consultants, trade associations, and marketing professionals in the medical device industry, health insurance industry, orthopedics and biologics fields, and ambulatory surgery and broader hospital sector would benefit from this report. Additionally, stock analysts, VC funders, and investors focused on the spine segment or those who are interested in expanding markets for orthopedic implants, minimally invasive surgical instrumentation and techniques, and biologic applications would also benefit. Manufacturers and distributors of the technology discussed in this report are also an INTENDED AUDIENCE.

INFORMATION SOURCESBCC Research reviewed reports, white papers, technical product specifications, and studies produced by industry, trade associations, corporations, professional organizations, payers, governments, healthcare providers, and peer-reviewed journal articles. Various original data sources were analyzed. Data were compiled from the U.S. Census Bureau, U.S. Patent and Trademark Office, the Department of Health and Human Services, and sub-agencies, including the FDA medical device data registry, CMS, AHRQ, CDC, and the National Center for Health Statistics. International data sources included WHO, OECD, Eurostat, Spine Tango, and databases from various countries' federal statistics offices. Interviews were conducted with industry sources, consultants, manufacturers, surgeons, and researchers.

Chapter- 1: INTRODUCTION -- Complimentary

INTRODUCTION 1

STUDY GOALS AND OBJECTIVES 2

REASONS FOR DOING THE STUDY 2

SCOPE OF REPORT 3

INTENDED AUDIENCE 3

INFORMATION SOURCES 4

ANALYST CREDENTIALS 4

RELATED BCC REPORTS 4

BCC ONLINE SERVICES 4

DISCLAIMER 5

Chapter-2: SUMMARY

SUMMARY 6

SUMMARY TABLE GLOBAL FORECAST SPINAL SURGICAL DEVICES BY CATEGORY, THROUGH 2015 ($ MILLIONS) 7

SUMMARY FIGURE
GLOBAL FORECAST SPINAL SURGICAL DEVICES BY CATEGORY, 2008-2015 ($ MILLIONS) 7

Chapter-3: OVERVIEW

SPINAL ANATOMY 8

SPINAL COLUMN 8

Intervertebral Discs 8

Boney Structures 9

NEURAL ELEMENTS 9

SUPPORTING STRUCTURES 9

TABLE 1 FUNCTIONAL ROLE OF THE SPINAL COLUMN COMPONENTS 10

BACK PAIN 10

HISTORY OF BACK PAIN AND EARLY TREATMENT 10

BACK PAIN TODAY 11

TABLE 2 GLOBAL SAMPLING OF FREQUENCY OF BACK PAIN, 2002–2009 12

Cost of Back Pain 12

TABLE 3 U.S. MEDICAL ENCOUNTERS BY SETTING FOR THE DIRECT TREATMENT OF BACK PROBLEMS, 2007 (THOUSANDS) 12

TABLE 4 HOSPITAL DISCHARGES BY BACK-RELATED DIAGNOSIS IN SELECT EUROPEAN COUNTRIES, THROUGH 2008 13

TABLE 5 U.S. DIRECT MEDICAL EXPENSES FOR BACK PROBLEMS, 2007 ($ MILLIONS) 14

TABLE 6 U.S. DISTRIBUTION OF DIRECT BACK-RELATED MEDICAL EXPENSES BY PAYER, 2007 (%) 14

TABLE 7 U.S. PATIENTS WITH BACK PROBLEMS, THROUGH 2007 (MILLIONS) 15

TABLE 8
U.S. MEDICAL EXPENDITURES FOR THE DIRECT TREATMENT OF BACK PROBLEMS, THROUGH 2007 ($ BILLIONS) 15

Disability from Back Pain 15

Identifying the Cause of Back Pain 16

TABLE 9 DISTRIBUTION OF DIAGNOSABLE BACK CONDITIONS (%) 16

Causes of Diagnosed Back Pain 16

Risk Factors for Back Pain 17

Risk Factors for Diagnosable Back Disorders 17

Genetics 17

Aging 17

TABLE
PROJECTED AGING OF THE GLOBAL POPULATION AGE 65 AND OLDER, THROUGH 2020 (MILLION) 18

Smoking 18

Obesity 19

TABLE
GLOBAL PREVALENCE OF OBESITY, 1995–2005 (%) 19

Osteoporosis 20

TABLE 12
PROJECTED AGING OF GLOBAL FEMALE POPULATION AGE 60–99, THROUGH 2020 (MILLION) 20

COMMON SPINAL CONDITIONS 20

TABLE 13
DIAGNOSIS-RELATED ICD 9 CODES FOR SPINAL CONDITIONS 21

TABLE 13 (CONTINUED) 22

TABLE 14
U.S. INPATIENTS DIAGNOSED BY CODED BACK CONDITIONS, 2008 22

ABNORMAL SPINAL CURVATURES 22

TABLE 15
U.S. TREND FOR INPATIENT DIAGNOSIS OF ALL ABNORMAL CURVATURES OF THE SPINE, THROUGH 2015 23

TABLE 16 U.S. INPATIENTS WITH ABNORMAL CURVATURES OF THE SPINE, 2008 23

Kyphosis 23

Postural Kyphosis 24

Structural Kyphosis 24

Gibbus Deformity 24

Scheuermann's Disease 24

Congenital Kyphosis 24

Secondary Kyphosis 24

Treatment 25

TABLE 17
GLOBAL FREQUENCY OF KYPHOSIS 25

TABLE 18 U.S. AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH KYPHOSIS, 2008 (%) 26

TABLE 19
U.S. TREND OF HOSPITAL INPATIENT DIAGNOSIS OF KYPHOSIS, THROUGH 2015 26

Lordosis 26

Treatment 27

TABLE 2
U.S. TREND FOR HOSPITAL INPATIENT DIAGNOSIS OF LORDOSIS, THROUGH 2015 27

Scoliosis 27

Congenital Scoliosis 27

Failure of Segmentation 28

Failure of Formation 28

Treatment 28

Neuromuscular Scoliosis 28

Treatment 29

Degenerative Scoliosis 29

Treatment 29

Idiopathic Scoliosis 29

Treatment 30

TABLE 2
GLOBAL FREQUENCY OF SCOLIOSIS 30

TABLE 22 U.S. AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH SCOLIOSIS, 2008 (%) 30

TABLE 23
U.S. TREND FOR HOSPITAL INPATIENT DIAGNOSIS OF SCOLIOSIS, THROUGH 2015 31

ARTHRITIC SPINAL CONDITIONS 31

TABLE 24
U.S. TREND FOR HOSPITAL INPATIENTS WITH DIAGNOSES OF ALL ARTHRITIS-RELATED SPINAL CONDITIONS, THROUGH 2015 31

TABLE 25
U.S. INPATIENTS WITH ARTHRITIS-RELATED SPINAL CONDITIONS, BY CONDITION, 2008 32

Ankylosing Spondylitis 32

TABLE 2
GLOBAL FREQUENCY OF ANKYLOSING SPONDYLITIS (%) 32

Rheumatoid Arthritis 33

TABLE 27
GLOBAL FREQUENCY OF RHEUMATOID ARTHRITIS (%) 33

TABLE 28 AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH ANKYLOSING SPONDYLITIS/RHEUMATOID ARTHRITIS (%) 34

TABLE 29
U.S. TREND FOR HOSPITAL INPATIENT DIAGNOSES OF ANKYLOSING SPONDYLITIS/RHEUMATOID ARTHRITIS, THROUGH 2015 34

Osteoarthritis/Spondylosis 34

TABLE 30  U.S. DISTRIBUTION OF SPONDYLOSIS BY SPINAL REGION, 2008 35

Treatment 35

TABLE 31 U.S. AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH SPONDYLOSIS, 2008 (%) 35

TABLE 32
U.S. TREND FOR HOSPITAL INPATIENT DIAGNOSIS OF SPONDYLOSIS, THROUGH 2015 36

DEGENERATIVE DISC DISEASES 36

TABLE 33
U.S. TREND FOR HOSPITAL INPATIENT DIAGNOSES WITH ALL DEGENERATIVE DISC DISEASES, THROUGH 2015 (THOUSANDS) 37

TABLE 34
U.S. INPATIENTS DIAGNOSED WITH DEGENERATIVE DISC DISORDERS, 2008 37

Disc Herniation 37

TABLE 35 U.S. DISTRIBUTION OF DISC HERNIATION BY SPINAL REGION, 2008 (%) 38

TABLE 36 U.S. AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH DISC HERNIATION, 2008 (%) 39

TABLE 37
U.S. TREND FOR INPATIENT DIAGNOSIS OF DISC HERNIATION, THROUGH 2015 (%) 39

Treatment 39

Disc Degeneration 40

TABLE 38 U.S. DISTRIBUTION OF DEGENERATIVE DIAGNOSIS BY REGION OF THE SPINE, 2008 (%) 40

TABLE 39 U.S. AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH DEGENERATION OF THE INTERVERTEBRAL DISCS, 2008 (%) 40

TABLE 40 U.S. TREND FOR INPATIENT DIAGNOSIS OF DEGENERATION OF THE INTERVERTEBRAL DISC, THROUGH 2015 (%) 41

Spinal Stenosis 41

TABLE 41 U.S. DISTRIBUTION OF STENOSIS BY SPINAL REGION, 2008 (%) 41

TABLE 42 U.S. AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH SPINAL STENOSIS, 2008 (%) 42

TABLE 43
U.S. TREND INPATIENT DIAGNOSIS OF SPINAL STENOSIS, THROUGH 2015 42

Treatment 42

Spondylolisthesis 42

TABLE 44 U.S. AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH SPONDYLOLISTHESIS, 2008 (%) 43

Treatment 44

TABLE 45
U.S. TREND IN INPATIENT DIAGNOSIS OF SPONDYLOLISTHESIS, THROUGH 2015 44

SPINAL TUMORS 44

Treatment 45

INJURY 45

Vertebral Fractures 45

TABLE 4
U.S. INPATIENTS WITH VERTEBRAL FRACTURE DIAGNOSIS, 2008 45

TABLE 47
U.S. AND E.U. VERTEBRAL FRACTURES BY TYPE 46

TABLE 48 U.S. AGE DISTRIBUTION FOR INPATIENTS DIAGNOSED WITH VERTEBRAL FRACTURES WITHOUT SPINAL CORD INJURY, 2008 (%) 46

TABLE 49
U.S. TREND FOR INPATIENT DIAGNOSIS OF VERTEBRAL FRACTURE, THROUGH 2015 (%) 47

Fracture Classification 47

Major/Minor 47

Stable/Unstable 47

Denis 3-Column Model 48

Break Type 48

Traumatic Spinal Injury 49

TRENDS IN FREQUENCY OF SPINAL CONDITIONS 50

TABLE 50 U.S. FORECAST FOR INPATIENT DIAGNOSIS BY CODED SPINAL CONDITION, THROUGH 2015 (THOUSANDS) 50

Chapter-4: MARKET ANALYSIS

MARKET BY APPLICATION OR PROCEDURE 51

TABLE 5
U.S. SPINAL PROCEDURES BY VOLUME, THROUGH 2015 (THOUSANDS) 51

TABLE 52
U.S. COSTS FOR ALL SPINAL PROCEDURES, THROUGH 2015 ($ MILLIONS) 52

TABLE 53 U.S. DISTRIBUTION OF SPINAL SURGERY PROCEDURES BY CATEGORY, 2008 (%) 53

TABLE 54
U.S. HIGHEST MEAN COSTS BY SPINAL SURGICAL PROCEDURE, 2008 ($) 53

Chapter-5: INDUSTRY PLAYERS Spinal Surgical Devices, Spinal Surgical Devices markets, technology Spinal Surgical Devices, spinal market , spinal devices, spinal surgery, orthopedic products, orthopedic products market, orthopedic devices, back surgery devices, implantable spinal surgical devices, spinal implants, spinal implants market, spinal implants technology, Spinal Devices manufacturers, HLC075A, Lori Solomon This report examines trends in the market for spinal surgical devices, specifically arthroplasty products and implanted instrumentation hardware. Includes forecasts through 2015.

FUSION 112

POSTERIOR PEDICLE SCREW FUSION SYSTEMS 112

Aesculap 112

Alphatec Spine, Inc. 113

Amedica Corp. 114

Biomet Spine 115

Cardo Medical, Inc. 116

Choice Spine, LP 117

Co-Ligne Ag 117

DePuy Spine, Inc. 117

DePuy Spine, Inc. (Continued) 118

DePuy Spine, Inc. (Continued) 119

Eden Spine, LLC 120

Exactech, Inc. 120

Globus Medical, Inc. 121

Innovasis, Inc. 122

Integra Spine 123

Interventional Spine, Inc. 124

Lanx, Inc. 125

LDR Medical 125

Life Spine 126

Medicrea International 127

Medtronic, Inc. 127

Neuro France Implants 128

NuVasive, Inc. 129

Ortho Development Corp. 129

Orthofix International N.V. 130

Orthofix … (Continued) 131

Pioneer Surgical Technology 132

Scient'X Group S.A.S. 132

SeaSpine, Inc. 133

Signus Medizintechnik GmbH 134

Sintea Biotech, SpA 134

Specialty Spine Products, LLC 135

Spine Network (Eurosurgical) 135

SpineVision SA 136

Stryker Spine 137

Stryker Spine (Continued) 138

Synthes Inc. 139

Ulrich GmbH & Co. KG 140

VertiFlex, Inc. 141

X-Spine Systems, Inc. 141

Zimmer Spine, Inc. 142

CABLE SYSTEMS 143

Biomet Spine 143

DePuy Spine, Inc. 144

Pioneer Surgical Technology 145

ANTERIOR CERVICAL PLATE SYSTEMS 145

Aesculap 145

Alphatec Spine, Inc. 146

Amedica Corp. 147

Apollo Spine 147

Biomet Spine 148

Cardo Medical Inc. 149

Choice Spine, LP 149

DePuy Spine, Inc. 150

Exactech, Inc. 151

Globus Medical, Inc. 151

Innovasis, Inc. 152

Integra Spine 152

Lanx, Inc. 153

Life Spine 154

NuVasive, Inc. 154

Ortho Development Corp. 155

Orthofix International N.V. 155

Pioneer Surgical Technology 156

Scient'X Group S.A.S. 157

SeaSpine, Inc. 157

Signus Medizintechnik GmbH 158

Sintea Biotech, SpA 158

SpineVision SA 158

Stryker Spine 159

Synthes Inc. 159

Ulrich GmbH & Co. KG 160

X-Spine Systems, Inc. 161

Zimmer Spine, Inc. 161

OTHER ANTERIOR FIXATION DEVICES 162

Alphatec Spine, Inc. 162

DePuy Spine, Inc. 162

DePuy Spine, Inc. (Continued) 163

Eminent Spine 164

Globus Medical, Inc. 164

Life Spine 165

Medicrea International 165

NuVasive, Inc. 165

Scient'X Group S.A.S. 166

SeaSpine, Inc. 167

Stryker Spine 167

Synthes Inc. 168

X-Spine Systems, Inc. 169

Ulrich GmbH & Co. KG 170

Zimmer Spine, Inc. 170

INTERBODY FUSION DEVICES 171

Vertebral Body Replacement 171

Aesculap 171

Alphatec Spine, Inc. 171

Biomet Spine 172

Co-Ligne Ag 173

DePuy Spine, Inc. 173

DePuy …. (Continued) 174

Eden Spine, LLC 175

Globus Medical, Inc. 175

Innovasis, Inc. 176

Integra Spine 176

Ortho Development Corp. 177

Orthofix International N.V. 178

Pioneer Surgical Technology 179

Scient'X Group S.A.S. 180

Signus Medizintechnik GmbH 180

SpineVision SA 181

Spine Wave, Inc. 182

Stryker Spine 182

Synthes, Inc. 183

Ulrich GmbH & Co. KG 184

Verticor, Ltd. 185

Metallic Interbody Fusion Devices 185

Aesculap 185

Life Spine 186

Osteotech, Inc. 186

Medtronic, Inc. 186

RSB Spine LLC 187

Scient'X Group S.A.S. 188

Sintea Biotech, SpA 188

SpineSelect, LLC 189

Stryker Spine 189

Titan Spine, LLC 190

TranS1, Inc. 190

Ulrich GmbH & Co. KG 191

Vertebration, Inc. 192

Zimmer Spine, Inc. 192

Polymer Interbody Fusion Devices 193

Aesculap 193

Alphatec Spine, Inc. 193

Amedica Corp. 194

Biomet Spine 195

Centinel Spine, Inc. 196

Choice Spine, LP 197

Co-Ligne AG 197

DePuy Spine, Inc. 198

Eminent Spine 199

Globus Medical, Inc. 199

Innovasis, Inc. 200

Integra Spine 201

LDR Medical 202

Lanx, Inc. 203

Medicrea International 203

Neuro France Implants 204

NuVasive, Inc. 205

Orthofix International N.V. 206

Scient'X Group S.A.S. 207

SeaSpine, Inc. 208

Signus Medizintechnik GmbH 209

Sintea Biotech, SpA 210

Spinal Elements 210

SpineSmith 211

Synthes Inc. 211

Ulrich GmbH & Co. KG 212

Vertebral Technologies, Inc. 213

Verticor, Ltd. 213

VertiFlex, Inc. 213

X-Spine Systems, Inc. 214

Zimmer Spine, Inc. 214

Structural Spinal Allografts 215

AlloSource 215

Alphatec Spine, Inc. 215

Biomet Spine 216

Lanx, Inc. 216

Ortho Development Corp. 217

Osteotech, Inc. 217

Scient'X Group S.A.S. 218

Stryker Spine 218

Synthes, Inc. 219

Zimmer Spine, Inc. 220

BONE GRAFTS 221

Demineralized Bone Matrix (DBM) 221

Alphatec Spine, Inc. 221

Biomet Spine 221

Citagenix, Inc. 222

Etex Corp. 223

Exactech, Inc. 223

Integra Spine 224

Osteotech, Inc. 225

Synthes, Inc. 226

Wright Medical Technology, Inc. 226

BONE GRAFT SUBSTITUTES 227

Amedica Corp. 227

Biocomposites, Ltd. 227

Citagenix, Inc. 228

DePuy Spine, Inc. 228

Etex Corp. 228

Globus Medical, Inc. 229

Innovasis, Inc. 230

Integra Spine 230

LDR Medical 231

Medicrea International 231

Medtronic, Inc. 232

NuVasive, Inc. 232

Orthovita 233

Progentix Orthobiology BV 233

Scient'X Group S.A.S. 234

Signus Medizintechnik GmbH 234

Synthes, Inc. 235

Wright Medical Technology, Inc. 235

Wright … (Continued) 236

Zimmer Spine, Inc. 237

PLATELET HELPERS 237

Stem Cells 237

Allosource 237

NuVasive, Inc. 238

Growth Factors (rhBMP) 238

BioMimetic Therapeutics, Inc. 238

Medtronic, Inc. 239

Stryker Spine 240

Non-Fusion 240

Interspinous Process Spacers 240

Eden Spine, LLC 240

Globus Medical, Inc. 241

Interventional Spine, Inc. 241

Medtronic, Inc. 242

Paradigm Spine, LLC 243

Privelop AG 243

Replication Medical, Inc. 243

VertiFlex, Inc. 244

Dynamic Stabilization 244

Applied Spine Technologies, Inc. 244

Bio-Spine Corp. 245

Disc Motion Technologies 245

Eden Spine, LLC 246

Paradigm Spine, LLC 246

Scient'X Group S.A.S. 247

SpineVision SA 247

Ulrich GmbH & Co. KG 248

VertiFlex, Inc. 248

Zimmer Spine, Inc. 249

Arthroplasty: Cervical 250

Aesculap 250

Globus Medical, Inc. 251

LDR Medical 251

Medicrea International 252

Medtronic, Inc. 252

NuVasive, Inc. 253

Orthofix International N.V. 253

Paradigm Spine, LLC 254

Scient'X Group S.A.S. 254

Signus Medizintechnik GmbH 255

Spinal Kinetics 255

Spinal Motion 256

Stryker Corp. 256

Synthes Inc. 257

Arthroplasty: Lumbar 257

Aesculap 257

AxioMed Spine Corp. 258

DePuy Spine, Inc. 259

Disc Motion Technologies 259

Eden Spine, LLC 259

Fournitures Hospitalieres Orthopedics 260

Integra Spine 260

LDR Medical 261

Pioneer Surgical Technology 262

Ranier Technology, Ltd. 262

Spinal Motion 263

Synthes Inc. 263

Zimmer Spine, Inc. 264

Nucleus Replacement 264

CryoLife Inc. 264

Gentis Inc. 265

Replication Medical, Inc. 265

Spine Wave, Inc. 266

TranS1, Inc. 266

Vertebral Technologies, Inc. 267

Facet Replacement 267

Facet Solutions, Inc. 267

Impliant, Inc. 268

Interventional Spine, Inc. 268

Spinal Elements 268

Vertebral Column Fracture 269

Alphatec Spine Inc. 269

ArthoCare Corp. 269

Benvenue Medical 270

Biomet Spine 270

Bone Solutions, Inc. 271

BoneSupport AB 272

CareFusion 272

DePuy Spine, Inc. 273

DFine, Inc. 273

Doctors Research Group, Inc. 274

Mathys, Ltd. Bettlach 274

Medtronic, Inc. 275

Orthovita 275

Sintea Biotech, SpA 276

SpineAlign Medical, Inc. 276

Stryker Corp. 277

Vexim SAS 277

Annulus Repair 278

Anulex Technologies, Inc. 278

Intrinsic Therapeutics, Inc. 278

Magellan Spine Technologies, Inc. 279

Chapter-6: REFERENCES

REFERENCES 280

REFERENCES (CONTINUED) 281

REFERENCES (CONTINUED) 282

To order this report:Surgical Equipment Industry: Spinal Surgical Devices: Technologies and Global Markets

Surgical Equipment Business News

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