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Reportlinker Adds Proteomics - Technologies, Markets and Companies

lternative splicing .. 22

Transcription . 23

Gene regulation 23

Gene expression .. 24

Chromatin .. 24

Proteins .. 25

Spliceosome 25

Functions of proteins 25

Inter-relationship of protein, mRNA and DNA 26

Proteomics . 27

Mitochondrial proteome . 28

S-nitrosoproteins in mitochondria 28

Proteomics and genomics .. 29

Classification of proteomics .. 31

Levels of functional genomics and various "omics" 31

Glycoproteomics .. 32

Transcriptomics 32

Metabolomics 32

Cytomics.. 33

Phenomics . 33

Proteomics and systems biology . 33

2. Proteomic Technologies 36

Key technologies driving proteomics 36

Sample preparation .. 37

New trends in sample preparation .. 37

Pressure Cycling Technology 38

Protein separation technologies . 38

High resolution 2D gel electrophoresis .. 38

Variations of 2D gel technology .. 39

Limitations of 2DGE and measures to overcome these . 39

1-D sodium dodecyl sulfate (SDS) PAGE .. 39

Capillary electrophoresis systems 40

Head column stacking capillary zone electrophoresis 40

Removal of albumin and IgG 40

Companies with protein separation technologies 41

Protein detection 42

Protein identification and characterization 42

Mass spectrometry (MS) 42

Companies involved in mass spectrometry 43

Electrospray ionization . 44

Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry 45

Cryogenic MALDI- Fourier Transform Mass Spectrometry . 46

Stable-isotope-dilution tandem mass spectrometry 47

HUPO Gold MS Protein Standard .. 47

High performance liquid chromatography . 47

Multidimensional protein identification technology (MudPIT) .. 47

Peptide mass fingerprinting .. 48

Combination of protein

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