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Reportlinker Adds Monoclonal Antibodies: 2010

arget pipeline analysis 148

Chapter 6 Key Products 157

Introduction 157

Oncology 158

Immunology & inflammation 171

Central nervous system 183

Infectious diseases 187

Musculoskeletal 191

Other 193

Chapter 7 Appendix 195

References 195

Abbreviations 197

Exchange rates 198

About Datamonitor 199

Datamonitor consulting 199

Disclaimer 201

TABLE OF TABLES Table 1: PharmaVitae company coverage by peer set 8

Table 2: Molecule type definitions 11

Table 3: General characteristics of small molecule drugs vs. biologics 13

Table 4: Prescription pharmaceutical sales by molecule type ($m), 2009–15 14

Table 5: Overview of a selection of marketed MAbs: technology type and immunogenicity 49

Table 6: Infix nomenclature for MAbs 61

Table 7: Global top five MAb sales ($m), 2002, 2008 and 2014 70

Table 8: Annual revenues of the Big 5 ($m), 2009 and 2015 71

Table 9: Historical MAb product sales ($m), 2003–09 74

Table 10: Forecast MAb product sales ($m), 2009–15 80

Table 11: Historical MAb sales by company ($m), 2003–09 89

Table 12: Forecast MAb sales by company ($m), 2009–15 92

Table 13: Historical MAb sales by therapy area ($m), 2003–09 97

Table 14: Forecast MAb sales by therapy area ($m), 2009–15 100

Table 15: Historical MAb sales by geography ($m), 2003–09 106

Table 16: Forecast MAb sales by geography ($m), 2009–15 107

Table 17: Historical MAb sales by technology ($m), 2003–09 111

Table 18: Forecast MAb sales by technology ($m), 2009–15 112

Table 19: Historical MAb sales by target ($m), 2003–09 117

Table 20: Forecast MAb sales by target ($m), 2009–15 118

Table 21: MAb pipeline overview, 20010 123

Table 22: Count of marketed mAbs by company, 2

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