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Reportlinker Adds Monoclonal Antibodies: 2010


About the PharmaVitae team 2

Chapter 1 About this Sector Report 3

PharmaVitae Explorer database 3

Chapter structure 3

Data sourcing 4

Chapter 2 Executive Summary 5

Key findings 5

Introduction to the PharmaVitae company universe 7

The prescription pharmaceutical market to 2015 9

The MAb market will deliver the largest and fastest sales growth across the industry 15

The MAb sector will remain the fastest growing across the pharmaceutical industry 22

Historical market analysis 23

Forecast market analysis 26

Chapter 3 MAb Technology Overview 40

Key findings 40

Introduction 41

Monoclonal antibodies as therapeutic agents 43

Evolution of MAbs 47

Antibody drug conjugates – an alternative 'combination therapy' 55

Bispecific antibodies – is now the time for commercial success? 57

Trifunctional antibodies – successful innovation in a niche indication 58

Ablynx's nanobodies 59

GSK's acquisition of Domantis gives it ownership of DAbs – will the leading Big Pharma player in inhalable drug delivery echo this into the antibody market? 60

Systematic naming of MAbs 61

The MAb timeline—technology evolution 61

Chapter 4 Market Analysis 67

Key findings 67

Introduction 68

MAb market product analysis, 2003–15 72

MAb market company analysis, 2003–15 88

MAb market therapy area analysis, 2003–15 96

MAb market geographic analysis, 2003–15 105

MAb market technology analysis, 2003–15 110

MAb market target analysis, 2003–15 116

Chapter 5 Pipeline Analysis 121

Key findings 121

Introduction 122

MAb pipeline overview 123

Company pipeline analysis 132

Technology pipeline analysis 141

Therapy area pipeline analysis 145


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