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Reportlinker Adds Global Anti-CD20 Monoclonal Antibodies Industry
Date:10/4/2010

FOCUS ON SELECT ANTI-CD20 MABS AVAILABLE WORLDWIDE II-14

APPROVED ANTI-CD20 ANTIBODIES IN A NUTSHELL II-14

Select Anti-CD20 Antibodies' Pipeline in a Nutshell II-14

Drug Details II-16

Rituxan/MabThera (Biogen, Roche and Genentech) II-16

Approved and Potential Indications for Rituxan II-17

Zevalin (Spectrum™ Pharmaceuticals) II-17

Bexxar (GlaxoSmithKline) II-18

Ofatumumab (Genmab and GlaxoSmithKline) II-18

Clinical Development of HuMax-CD20 by Indication and Stage

of Development II-19

Ocrelizumab (Biogen/Genentech) II-19

Summary of Ocrelizumab Development Status II-20

GA-101 (Roche/GlycArt) II-20

TRU-015 (Trubion) II-21

AME-133v (Eli Lilly) II-21

Veltuzumab (Immunomedics/Nycomed) II-22

Clinical Trials of Veltuzumab II-22

BVX-20 (Biocon) II-23

LFB-R603 (LFB Biotechnlogies) II-23

DXL625 (InNexus) II-23

4. PRODUCT OVERVIEW II-24

CD20 Antibody II-24

Immune System: Natural Defenders II-24

Human Antibodies II-24

Types of Monoclonal Antibodies II-24

Table 3: Worldwide mAb Market By Product Type (2008):

Percentage Share Breakdown For Chimeric, Humanized, Human And

Murine (includes corresponding Graph/Chart) II-24

Chimeric Antibodies: Show Lesser Antigenicity II-25

Murine Monoclonal Antibodies II-25

Humanized Antibodies/ CDR Grafted Antibodies (Human Antibodies) II-25

Fully Human Antibodies II-26

Bispecific Antibodies II-26

5. A PEEK INTO MONOCLOBAL ANTIBODY MARKET II-27

EVOLUTION OF MONOCLONAL ANTIBODIES – A HISTORICAL JOURNEY II-27

Market Perspective of mAbs II-28

Regional Perspective II-28

Significant Growth Awaits mAbs II-28

Shift Towards Humanized and Fully Human Antibodies II-29

Ageing Baby Boomers Spur MAbs Growth II-30

Non-Existent Generic Competition Favors MAb Market II-3
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