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Internal Analgesics - The Largest & Fastest Growing Market 5
Liquid Analgesics Register Rapid Growth 6
Neuropathic Pain - Unexplored 6
Ibuprofen Scoring High 6
External Analgesics - Loosing Sheen 6
Topical Analgesics Market: Current Picture 7
Competitive Scenario 7
Global Analgesics Market (2007): Leading Analgesics Brands by
Manufacturer 7
3. PRODUCT OVERVIEW 8
A Brief History 8
Analgesics 8
Definition 8
Types of Pain 8
Acute Pain 8
Chronic Pain 9
Drugs Combating Pain 9
Local Anesthetics 9
Narcotic Opioids 10
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) 10
Types of NSAIDS 10
Common NSAIDs 11
Clinical Use... 12
Side Effects... 12
Aspirin 13
The Wonder Drug... 13
PolyAspirin: The Safer and More Potent Polymer Variant of
Aspirin 13
Mode of Action 13
Contraindications 14
Acetaminophen 14
Acetaminophen Protects Heart Muscle 14
Acetaminophen Reduces Incidence of Ovarian Cancer 15
Ibuprofen, Ketoprofen and Naproxen 15
Combination Analgesics 15
Table 1: Opioid Analgesics Market: Percentage Share of Opioid
/ Acetaminophen Combination Products in the Opioid Script
Volume (includes corresponding Graph/Chart) 16
OTC Analgesics: An Overview 16
4. INDUSTRY DYNAMICS 17
Escalating R&D Costs: A Boon or Bane? 17
Timeline of the Drug Approval Process 17
Cox II Crisis Tarnishes Industry Growth 17
Novel Therapies to Propel Opioid and Non-Opioid Therapies 18
Rx-to-OTC Switch 18
Why Consumers Prefer OTC Drugs? 18
Development of Analgesic Tripeptides 18
5. RECENT CLINICAL TRIALS 19
PLx Initiates Clinical Trial For Aspirin-PC 19
Neurodiscovery Receives Approval for NSL-101 Phase II Clinical
Tri
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