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Reportlinker Adds Drug Delivery in Central Nervous System Diseases - technologies,markets and companies
Date:9/7/2010

enetration of molecules across the BBB 34

Table 2 3: Enzymes that control the penetration of molecules across the BBB 36

Table 2 4: Factors that increase the permeability of the BBB 41

Table 2 5: Diseases that affect the BBB 42

Table 3 1: Various methods of drug delivery to the central nervous system 55

Table 3 2: Drugs available for intrathecal administration 62

Table 3 3: Strategies for drug delivery to the CNS across the BBB 65

Table 3 4: Specific inhibitors of P-glycoprotein in clinical development 70

Table 3 5: Molecules attached to Trojan horses injected intravenously for CNS effect 75

Table 3 6: Examples of controlled and sustained release drug delivery for CNS disorders 87

Table 3 7: Novel methods of delivery of drugs for CNS disorders 89

Table 3 8: Indications for the clinical applications of NTFs in neurologic disorders 93

Table 3 9: Methods for delivery of neurotrophic factors to the CNS 94

Table 4 1: Methods for delivering cell therapies in CNS disorders 104

Table 4 2: Classification of methods of gene therapy 107

Table 4 3: Methods of gene transfer as applied to neurologic disorders 108

Table 4 4: Potential indications for gene therapy of neurologic disorders 114

Table 4 5: Companies developing cell/gene therapies for CNS disorders 115

Table 4 6: Methods of antisense delivery as applied to the CNS 117

Table 5 1: Strategies for the treatment of Parkinson's disease 125

Table 5 2: Drug delivery systems for Parkinson's disease 127

Table 5 3: Types of cell used for investigative treatment of Parkinson's disease 131

Table 5 4: Status of cell therapies in development for Parkinson's disease 131

Table 5 5: Gene therapy techniques applicable to Parkinson disease 137

Table 5 6: Companies developing gene therapy for Parkinson's disease 141

Table 5 7: Classification of pharmacotherapy for Alzh
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