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Reportlinker Adds Competitor Analysis: PI3K-AKT-mTOR Inhibitors
Date:10/16/2009

NEW YORK, Oct. 16 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue.

Reportlinker Adds Competitor Analysis: PI3K-AKT-mTOR Inhibitors

http://www.reportlinker.com/p0154665/Reportlinker-Adds-Competitor-Analysis-PI3K-AKT-mTOR-Inhibitors.html

Product description

The present Competitive Intelligence Report about PI3K-AKT-mTOR Inhibitors provides a competitor evaluation in the field of novel molecular entities inhibiting members of the phosphatidyl-inositol-3 kinase (PI3K) / Akt / mammalian target of rapamycin (mTOR) pathway for treatment of cancer or inflammatory diseases as of July 2009. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report.

The phosphatidylinositol-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in the regulation of cellular growth, survival, and proliferation. Dysregulation of this pathway, as a result of genetic mutations and amplifications, is implicated in a variety of human cancers. Therefore, each of the three components of the pathway alone and in combination has emerged as a key target for the treatment of cancer. While first generation therapeutic agents currently in clinical evaluation preferably are pan-PI3K inhibitors, next generation selective PI3K inhibitors are targeting one or several different subclasses.

However, only a short time ago, the paradigm existed that
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