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Reportlinker Adds 2010 Pharmaceuticals Research Review
Date:12/14/2010

SES OF TYPICAL ANTIPSYCHOTICS ON THE MARKET AND THEIR SIDE EFFECTS 126

ATYPICAL ANTIPSYCHOTICS 127

TABLE 39 CURRENTLY APPROVED ATYPICAL ANTIPSYCHOTICS ON THE MARKET 128

TABLE 39 (CONTINUED) 129

TABLE 40 FEATURES OF TYPICAL VERSUS ATYPICAL ANTIPSYCHOTICS 130

TABLE 41 COST OF SELECTED ATYPICAL AND TYPICAL ANTIPSYCHOTIC DRUGS ($) 130

TABLE 41 (CONTINUED) 131

RECEPTOR TARGETS OF ANTIPSYCHOTIC DRUGS 131

DOPAMINE 131

SEROTONIN 132

GLUTAMATE 133

TACHYKININ 134

GLUCOCORTICOID 135

SIDE EFFECTS OF ANTIPSYCHOTICS 135

NEUROLOGIC SIDE EFFECTS (EXTRAPYRAMIDAL SYMPTOMS) 135

ANTICHOLINERGIC SIDE EFFECTS 136

CARDIOVASCULAR SIDE EFFECTS 137

METABOLIC SIDE EFFECTS 138

OTHER SIDE EFFECTS 138

TABLE 42 COMPARISON OF SIDE EFFECT PROFILES OF ANTIPSYCHOTICS ON THE MARKET 139

ANTIPSYCHOTICS IN CLINICAL DEVELOPMENT 139

TABLE 43 ANTIPSYCHOTICS IN CLINICAL TRIALS, ORDERED BY PHASE 140

TABLE 43 (CONTINUED) 141

TABLE 44 NUMBER OF ANTIPSYCHOTICS IN CLINICAL TRIALS, BY PHASE (NUMBER/%) 141

FIGURE 13 ANTIPSYCHOTICS IN CLINICAL TRIALS BY PRIMARY RECEPTOR TARGET 142

TABLE 45 COMPANIES WITH MORE THAN ONE ANTIPSYCHOTICS IN CLINICAL TRIALS OR ON THE MARKET* 143

Chapter-8: UBIQUITIN PROTEOSOME DRUGS: CANCER AND NEURODEGENERATIVE DISORDER

INTRODUCTION 144

STUDY GOALS AND OBJECTIVES 144

REASONS FOR DOING THIS STUDY 144

SCOPE OF REPORT 144

METHODOLOGY AND INFORMATION SOURCES 145

INTENDED AUDIENCE 145

ANALYST CREDENTIALS 145

RELATED BCC REPORTS 146

SUMMARY 146

TABLE 46 U.S. AND WORLDWIDE NET SALES OF VELCADE, THROUGH 2015 ($ MILLIONS) 147

FIGURE 14 U.S. AND WORLDWIDE NET SALES OF VELCADE, 2007-2015 ($ MILLIONS) 148

FIGURE 15 GLOBAL MARKET SHARES OF MILLENNIUM/TAKEDA, CELGEN
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