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Reportlinker Adds 2010 Pharmaceuticals Research Review
Date:12/14/2010

rial Particles Destroy Drug-Resistant Germs 71

Biodegradable Cationic Core-Shell Nanoparticles for Co-delivery of Drugs and Genes 72

Stimuli-Sensitive Core-Shell Nanoparticles for Cancer Therapy 72

Polymer-Based Non-Viral Gene Carriers 73

POTENTIAL HEALTH EFFECTS: IMPACT ON NANO INDUSTRY 73

Potential Health Effects: … (Continued) 74

TABLE 20 REVENUES ATTRIBUTABLE TO NANOTECHNOLOGY-BASED DRUG-DEVICE COMBINATIONS, THROUGH 2014 $ MILLIONS 75

Chapter-5: CARDIOVASCULAR THERAPEUTIC DRUGS: TECHNOLOGIES AND GLOBAL MARKETS (PHM024B)

INTRODUCTION 76

STUDY GOALS AND OBJECTIVES 76

REASONS FOR DOING THE STUDY 76

SCOPE OF REPORT 77

INTENDED AUDIENCE 78

METHODOLOGY AND INFORMATION SOURCES 79

RELATED BCC REPORTS 79

BCC ONLINE SERVICES 79

DISCLAIMER 80

SUMMARY 80

TABLE 21 GLOBAL CARDIOVASCULAR FORECAST BY DISEASE CLASS, THROUGH 2015 ($ MILLIONS) 80

FIGURE 5 GLOBAL CARDIOVASCULAR FORECAST BY DISEASE CLASS, 2007-2015 ($ MILLIONS) 81

OVERVIEW 82

CURRENT STATE OF CARDIOVASCULAR DISEASE 82

FIGURE 6 LEADING CAUSES OF DEATH IN THE UNITED STATES; 2006 (DEATHS PER 100,000) 83

ESTABLISHED DRUG CLASSES IN CARDIOVASCULAR DISEASE 84

Statins 84

Angiotensin Receptor Blocker 85

Angiotensin Converting Enzyme (ACE) inhibitors 85

EMERGING DRUG CLASSES 86

P2Y12 Inhibitors and Antagonists 86

Factor Xa Inhibitors 86

Cholesterol-Ester Transfer Protein (CETP) Inhibitor 87

TABLE 22 CETP INHIBITORS IN ACTIVE DEVELOPMENT 87

KEY RECENT EVENTS IN THE CARDIOVASCULAR MARKET 87

Plavix Metabolizer 2C19 Triggers U.S. Warning 87

VALTURNA IS FIRST TO RECEIVE U.S. APPROVAL AS COMBINATION THERAPY FOR HYPERTENSION 88

SUMMARY PIPELINE OF DRUGS IN DEVELOPMENT 89

TABLE 23 RECENTLY APPROVED DRUGS 89

TABLE 24 SUMMARY PIP
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