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Reportlinker Adds 2010 Pharmaceuticals Research Review
Date:12/14/2010

LIONS) 161

Celgene 161

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Revlimid 161

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Thalomid 162

TABLE 52 WORLDWIDE NET SALES OF REVLIMID AND THALOMID, THROUGH 2016 ($ MILLIONS) 162

FIGURE 20 WORLDWIDE NET SALES OF REVLIMID AND THALOMID, 2006-2016 ($ MILLIONS) 163

Market Shares of Millennium/Takeda, Celgene, and Other Companies' Drugs 163

TABLE 53 WORLDWIDE SHARES OF THE MM TREATMENT MARKET: MILLENNIUM/TAKEDA, CELGENE, AND OTHER DRUG COMPANY SHARES IN 2009 COMPARED TO THOSE PROJECTED IN 2011* (%) 164

FIGURE 21 WORLDWIDE SHARES OF THE MM TREATMENT MARKET: MILLENNIUM/TAKEDA, CELGENE, AND OTHER DRUG COMPANY SHARES IN 2009 COMPARED TO PROJECTED SHARES IN 2011* (%) 164

FIGURE 21 (CONTINUED) 165

Millennium Pharmaceuticals/Takeda's New Developments 165

TABLE 54 EXAMPLE OF COSTS OF SIDE EFFECTS OF CHEMOTHERAPY TREATMENT PER PATIENT IN THE U.S., 2006 ($ THOUSANDS) 166

New Formulations for Velcade and Second-Generation Inhibitors 166

Improvement of Velcade 166

Second-Generation Inhibitor MLN9708 166

TABLE 55 CURRENT R&D ACTIVITY IN UPS BY MILLENNIUM/TAKEDA 167

Velcade in Combination with Other Treatments 167

COMPANIES WORKING ON SECOND-GENERATION PROTEASOME INHIBITORS 167

OVERVIEW 167

Current Market Participants 167

TABLE 56 COMPANIES WITH CURRENT R&D IN PROTEASOME INHIBITION AS A DRUG TARGET 168

Millennium Pharmaceuticals (a Subsidiary of Takeda) 168

Onyx Pharmaceuticals/Proteolix 168

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Carfilzomib 168

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ONX 0912 169

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ONX 0914 (PR-957) 169

TABLE 57 WORLDWIDE MARKET FOR AUTOIMMUNE DISORDERS: LUPUS, RA, AND IBD, 2008 ($ BILLIONS) 170

Cephalon 170

• CEP-18770 170

Nereus Pharmaceuticals 170

• Salinosporamide (NPI-0052) 170

Salinosporamide … (Continued) 171

Chapter-9: ONCOL
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