Navigation Links
Reportlinker Adds 2010 Pharmaceuticals Research Review
Date:12/14/2010

E, AND OTHER DRUG COMPANIES, 2009 (%) 148

FIGURE 15 (CONTINUED) 149

OVERVIEW OF SCIENTIFIC BACKGROUND, AND SIGNIFICANCE OF UPS RESEARCH 149

UBIQUITINATION PHENOMENA AND ITS MAJOR COMPONENTS 149

Enzymatic Components as Possible Drug Targets 149

TABLE 47 ENZYMATIC COMPONENTS OF UBIQTUINATION/ DEUBIQUITINATION REACTION 150

FIGURE 16 ENZYMATIC STEPS IN UBIQUITINATION REACTION 150

FIGURE 17 HIERARCHICAL STRUCTURE OF UPS 151

Chain Topology as a Signaling Pathway 151

PROTEASOME MACHINERY 152

STRUCTURE AND FUNCTION 152

PROTEASOME AS A TARGET FOR DRUG DISCOVERY 153

UBIQUITIN-LIKE MODIFIERS (UBLS) 153

TABLE 48 UBLS, THEIR FUNCTION AND ASSOCIATED PATHOLOGY WITH THEIR DYSFUNCTION 154

MAJOR DRUG DEVELOPMENT AND PRODUCTS IN THE UPS RESEARCH FIELD 155

INDUSTRY OVERVIEW 155

Proteasome as a Drug Discovery 155

Velcade: The First UPS Product 155

Chemical Structure of Velcade and Its Mechanism of Action 156

FIGURE 18 CHEMICAL STRUCTURE OF BORTEZOMIB 156

Pharmacodynamics, Administration, and Side Effects 156

Velcade Sales Market 157

Overview 157

TABLE 49 U.S. STATISTICS FOR HEMATOLOGICAL MALIGNANCIES, 2009 (NUMBER) 157

MM Symptoms and Treatment 158

General Treatment for MM Today 158

TABLE 50 PROJECTED SIZE OF THE WORLDWIDE MM DRUG MARKET, 2009 AND 2018 ($ BILLIONS) 159

NHL and Mantle Cell Lymphoma 159

·
Treatments for Mantle Cell Lymphoma and Other NHL 159

·
CHOP Therapy 159

·
MabThera/Rituxan 159

Current Major Market Participants in MM Treatment and Sales Forecast 160

Millennium Pharmaceuticals (a Subsidiary of Takeda) 160

TABLE 51 U.S. AND WORLDWIDE NET SALES OF VELCADE, THROUGH 2015 ($ MILLIONS) 160

FIGURE 19 U.S. AND WORLDWIDE NET SALES OF VELCADE, 2007-2015 ($ MIL
'/>"/>

SOURCE Reportlinker
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14

Related medicine technology :

1. Reportlinker Adds US Disposable Medical Supplies Market Report
2. Reportlinker Adds Gilead Sciences Inc.: PharmaVitae Profile
3. Reportlinker Adds Drug Delivery Partnering Agreements in Pharma and Biotech
4. Reportlinker Adds Global Medical Devices Industry Outlook to 2010: Marketing And Sales Strategies And The Impact of Recession And Recovery
5. Reportlinker Adds Reinventing Pharmaceutical Sales Forces
6. Reportlinker Adds Computer Assisted Coding Of Medical Information Market Shares, Strategies, and Forecasts 2008 to 2014
7. Reportlinker Adds Global Drug Manufacturing Industry Outlook to 2010: Marketing and Sales Strategies and the Impact of Recession and Recovery
8. Reportlinker Adds Global Anesthesia and Respiratory Devices Market Analysis and Forecasts to 2015
9. Reportlinker Adds The Middle Eastern Pharmaceutical Market Outlook To 2014: Policy environment, market structure, competitive landscape, growth opportunities
10. Reportlinker Adds Global Top 10 Chemical Companies -- Industry, Financial and SWOT Analysis
11. Reportlinker Adds Pharma 101: An Overview of the Life Sciences Industry (Analyst Insight)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... May 22, 2015  The Mesothelioma Victims Center ... of mesothelioma get the best possible compensation, and they ... with this rare cancer caused by exposure to ... information related to treatment options such as a ... the Mesothelioma Victims Center anytime at 866-714-6466. ...
(Date:5/22/2015)... , May 22, 2015 Today, Rhodes ... nervous system stimulant indicated for the treatment of ... beginning Summer 2015. The announcement ... approval from the U.S. Food and Drug Administration ... extended-release formulation of methylphenidate capsule with an onset ...
(Date:5/21/2015)... 2015 Research and ... addition of the "North American Joint ... Replacement, Elbow Replacement, Hip Replacement, Knee Replacement, ... report to their offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... valued at $4,470.9 million in 2014 and ...
Breaking Medicine Technology:Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 2Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 3Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 4Mesothelioma Victims Center Calls Attention to a Recent Medical Article About a New Drug That Could Slow the Progression of Mesothelioma and Allow People to Live Longer 5Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 2Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 3Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 4Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 5Rhodes Pharmaceuticals Announces Launch of New, Once-Daily Treatment for ADHD 6North American Joint Reconstruction Market 2015-2019 - Zimmer Holdings, DePuy Synthes Companies, Stryker, Biomet & Smith & Nephew Dominates the $4.4 Billion Market 2
... Sept. 7, 2011 Prescription monitoring laboratory and ... comprehensive program, its Safe Use Treatment Monitoring Solution™. ... Use is compliant with the FDA,s Opioid Risk ... Prescribing Regulations for controlled substances.  The program aims ...
... MARY, Fla., Sept. 7, 2011 PediaVision today announced ... children across America.  This revolutionary new technology, Spot ... accuracy and deliver immediate comprehensive results.   ... of less than one second which makes ...
Cached Medicine Technology:Dominion Diagnostics Leads Fight Against Prescription Drug Abuse with Safe Use Treatment Monitoring Solution 2PediaVision Announces Record New Orders for Revolutionary New Vision Screening Device, Spot 2PediaVision Announces Record New Orders for Revolutionary New Vision Screening Device, Spot 3PediaVision Announces Record New Orders for Revolutionary New Vision Screening Device, Spot 4
(Date:5/23/2015)... On May 13, Nithyananda Yoga Foundation organized a ... learned through meditation and initiation at Special Holistic School ... Yogamaatha, a nine-year-old girl from North Carolina, stunned an ... the 2015 Business Advocacy Summit at Capitol Hill in ... In a demonstration that lasted three hours, Yogamaatha was ...
(Date:5/23/2015)... CO (PRWEB) May 23, 2015 On May ... in MuckFest. The event was a 5k mud obstacle run ... more than 2 million people worldwide, and the reason we ... community,” said Chad Davis, owner of Farrell’s eXtreme Bodyshaping. “One-hundred ... Multiple Sclerosis Society.” , The event was not only attended ...
(Date:5/23/2015)... Add High-Quality prismatic refractions into footage using ProFlare ... simple as dragging and dropping footage into the FCPX timeline ... , Including over 80 stunning flares, ProFlare 5K Prism ... the ultimate bundle for adding prismatic refractions to any video. ... movie files designed for Final Cut Pro X, but are ...
(Date:5/22/2015)... (PRWEB) May 22, 2015 The American ... exciting events in June. They will hold a webinar ... and a two-day class on Classical Chinese Medicine. , ... 3, Dr. Steve Given, the Dean of Clinical Education, ... the new First Professional Doctorate program. ACTCM is currently ...
(Date:5/22/2015)... Following yesterday’s announcement that Ascenta Health Limited has ... Nature’s Way, Marc St-Onge has affirmed his commitment to ... an integral part of the agreement with Nature’s Way ... develop Ascenta Skin into a leading player in the ... anti-aging skincare supplement featuring 6 active ingredients including therapeutic ...
Breaking Medicine News(10 mins):Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 2Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 3Health News:Farrell’s eXtreme Bodyshaping Team Runs through the Muck for MS 2Health News:Developers at Pixel Film Studios Release ProFlare 5K Prism for Final Cut Pro X. 2Health News:ACTCM Announces Upcoming June Events 2Health News:Ascenta Skin President Announces Plans to Grow Brand 2
... A Michigan State University surgeon is teaming up with ... create a simple, cost-effective saliva test to detect oral cancer, ... fewer people dying of the world,s sixth most common cancer. ... Medicine,s Department of Surgery and lead investigator on the project, ...
... TUESDAY, April 17 (HealthDay News) -- The ability to make ... changes in the brain,s white matter, a new imaging study ... 85, to perform a learning task involving money and also ... in decision-making are associated with the weakening of two specific ...
... Mothers with depression may behave in ways that disturb their ... University researchers conducted home visits with 45 mothers and their ... over 7 consecutive days to collect information about depression symptoms ... Greater amounts of sleep disruption were noted in infants whose ...
... TUESDAY, April 17 (HealthDay News) -- New research adds to ... (protein) plaques, the brain-clogging fragments that have been associated with ... Healthcare Berlin, researchers report that they were able to use ... the brains of patients whose Alzheimer,s was confirmed after death. ...
... HealthDay Reporter , TUESDAY, April 17 (HealthDay News) -- ... appear to get no survival benefit from adding the ... Cancer Institute report. An earlier trial had found ... patients aged 65 and older. Even so, the researchers ...
... drug bevacizumab (Avastin) to the standard chemotherapy regimen for non-small ... FDA in 2006 did not lead to significantly increase ... in Medicare, a new study by Dana-Farber Cancer Institute researchers ... April 18 Journal of the American Medical Association , ...
Cached Medicine News:Health News:Saliva test could dramatically increase detection of oral cancer 2Health News:Depressed Moms May Hinder Babies' Sleep 2Health News:New Method to Reveal Alzheimer's Marker Shows Promise 2Health News:Avastin No Benefit to Older Lung Cancer Patients: Study 2Health News:Avastin No Benefit to Older Lung Cancer Patients: Study 3Health News:Adding drug to standard chemotherapy provides no survival benefit for older lung cancer patients 2
... with 96-well plates in mind, Pipetman ... molecular biology applications: PCR* sequencing, immunology ... etc. Used with Diamond Tips from ... product will maximize performance and assure ...
... Finnpipette Focus multichannel ... dispensing of reagents into ... for 0.1-10 l volumes. ... of Finnpipette Focus multichannels, ...
... Long series in colonies, rows, and microplatesthat ... the multichannel pipette is becoming an ever-increasing ... use) was the main reason that the ... 8- or 12-channel pipette provides effective, precise, ...
... Focus multichannel pipettes speed ... reagents into microplates, with ... l volumes. The improved ... Focus multichannels, combined with ...
Medicine Products: