Navigation Links
Repligen Initiates Phase 3 Clinical Trial of RG1068 for Pancreatic MRI Imaging
Date:3/26/2008

WALTHAM, Mass., March 26 /PRNewswire-FirstCall/ -- Repligen Corporation (Nasdaq: RGEN) announced today that the Company has initiated a Phase 3 clinical trial to evaluate the use of RG1068, synthetic human secretin, to improve the assessment of pancreatic duct structures by magnetic resonance imaging (MRI). This Phase 3 study is a multi-center, baseline-controlled, single dose study in which approximately 250 patients will receive an unenhanced MRI followed by a secretin-enhanced MRI of the pancreas. This study is designed to assess the sensitivity and specificity of secretin- enhanced MRI to improve the ability to detect pancreatic duct abnormalities relative to MRI alone. Detailed visual assessment of the pancreatic ducts is important in the assessment, diagnosis and treatment of diseases such as acute and chronic pancreatitis. This study is being conducted at approximately 30 clinical sites within the United States and Canada.

"Based on discussions with the FDA, we believe a single positive Phase 3 clinical trial of similar design to our Phase 2 study will be sufficient for an NDA filing," stated Walter C. Herlihy, President and Chief Executive Officer of Repligen Corporation. "There are approximately 150,000 pancreatic MRI's conducted in the U.S. each year that could benefit from enhancement with secretin."

Repligen previously conducted a multi-center, baseline-controlled, single dose Phase 2 study in which 76 patients with a history of pancreatitis received an unenhanced pancreatic MRI followed by a RG1068 enhanced pancreatic MRI. The results of the study showed an improvement in sensitivity of detection of structural abnormalities of the pancreatic duct of approximately 20% with no loss in specificity. In addition, the
'/>"/>

SOURCE Repligen Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Repligen Reports Positive Phase 2a Clinical Trial Results of RG2417 for Symptoms of Bipolar Disorder
2. Carrington Subsidiary DelSite Initiates Critical Toxicology Studies of Its Nasal Powder Bird Flu Vaccine
3. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
4. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
5. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
6. MedImmune Initiates Phase 2a Multi-Dose Study in Patients with Asthma
7. Genta Initiates Phase 3 AGENDA Trial of Genasense(R) for Patients with Advanced Melanoma
8. Nuvelo Re-Initiates SONOMA-3 Trial of Alfimeprase in Patients With Catheter Occlusion
9. TorreyPines Therapeutics Initiates a Phase I Multiple Dose Clinical Trial of Tezampanel
10. Prolexys Pharmaceuticals Initiates Phase 1 Study
11. Isis Initiates Phase 1 Study of ISIS 325568 Targeting Glucagon Receptor to Treat Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... 23, 2015  A new analysis of Centers for Medicare ... data shows that 81 percent of seniors chose lower-cost ... discounts at certain pharmacies. The findings were released by ... are now the foundation of Medicare Part D," said ...
(Date:1/23/2015)... More than a third of reproductive-aged women enrolled in ... insurance, filled a prescription for an opioid pain medication each ... Morbidity and Mortality Weekly Report (MMWR). Opioids ... to severe pain.  They are also found in some prescription ...
(Date:1/23/2015)...  Pete Rose, baseball,s all-time hits leader, is the new spokesperson ... Ducere Pharma has announced. "Pete,s a Hall of ... him on board with Myoflex," said Ducere Pharma Chief Executive ... who is known across all generations. The passion and intensity ...
Breaking Medicine Technology:New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3Pete Rose bets on Myoflex to relieve aches and pains 2
... the market leader in automated revenue integrity solutions, ... Regional Medical Center, a 235-bed non-profit medical center ... nation,s five star hospitals in community value, Kingman ... to the range of Craneware Revenue Integrity Solutions™ ...
... Mass., June 2, 2011 Cynosure, Inc. (NASDAQ: ... minimally invasive and non-invasive aesthetic applications, today announced that it ... 1:30 p.m. (ET) on Thursday, June 9 in New York ... CEO Michael Davin and Executive Vice President, Treasurer and CFO ...
Cached Medicine Technology:Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 2Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 3Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 4
(Date:1/22/2015)... January 22, 2015 Padre Murphy's and Owner ... of Pro Player Health Alliance (PPHA). The PPHA's ... in getting everyone, including NFL greats, treated for obstructive sleep ... leading groups supporting the cause in the valley. The most ...
(Date:1/22/2015)... January 22, 2015 Blue Cross and Blue ... who exemplify what it means to “Live Fearless.” ... people to share their stories about how they or someone ... inspired others by living in the moment. By telling these ...
(Date:1/22/2015)... A new white paper by The Beryl ... the long-term care environment as well as provides recommendations ... paper, “The Power of Person-Centeredness in Long-Term Care: A ... the patient, resident and family experience in long-term care ...
(Date:1/22/2015)... January 22, 2015 Carinsurancesavings.biz has released a ... death and dismemberment insurance . , Purchasing an accidental ... be very advantageous. This type of rider provides benefits if ... can be considered a lesser form of life insurance. ...
(Date:1/22/2015)... Weddingshe.com has added many trendy Champagne wedding dresses ... in the past three years. Today, the business announces a ... to the sales manager of the company, this is on ... This point can be reflected on the discounted wedding dresses ...
Breaking Medicine News(10 mins):Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2
... Expansion ... CP,s Declared Uncertainty, ROCHESTER, Minn., Feb. 1 Mayo ... mitigation for,the city of Rochester as a condition of the ... (DM&E). The,proposed merger currently ignores the significant environmental impacts,created by ...
... Beaumont Technology,Usability Center will begin research on the ... study on tubing and catheter misconnection errors., ... Event Alert on the,potential dangers of tubing misconnections. ... of permanent loss of function were due to ...
... new ways to tackle certain diseases could be provided by ... to a Perspective article published today in the journal Nature ... microbes live symbiotically in the human gut. They play a ... inside the body. Different people have different types of gut ...
... but preventable, and urges better pediatric controls , , FRIDAY, ... unintended harm or suffering caused by health care -- ... new French research. , These IEs are sometimes serious ... Hospital in Marseille, France. , They looked at 388 ...
... Health,sponsors the Kaiser Permanente San Francisco Half Marathon & ... the Hemophilia Foundation of,Northern California, Support for Families of ... to take place on Feb. 3, this RRCA Western ... as one of the most scenic,in the country by ...
... and goodwill that,epitomise Christmas and the New Year. It is ... partying., This can be one of the worst times ... parties, neighbours, parties; it goes on and,on. Then comes January ... some the merriment of Christmas and the New Year masks ...
Cached Medicine News:Health News:Mayo Clinic Seeks Mitigation for Rochester as Condition of Canadian Pacific - DM&E Railroad Merger 2Health News:Mayo Clinic Seeks Mitigation for Rochester as Condition of Canadian Pacific - DM&E Railroad Merger 3Health News:Mayo Clinic Seeks Mitigation for Rochester as Condition of Canadian Pacific - DM&E Railroad Merger 4Health News:FDA Renews its Contract with Beaumont Technology Usability Center for Leadership of Patient Safety Project 2Health News:Targeting gut bugs could revolutionize future drugs, say researcher 2Health News:Unintended Errors Leave Many Newborns Vulnerable 2Health News:A Festive White Knuckle Ride? 2
... the MAMMOTOME® HH (Hand Held) ... procedure using ultrasound imaging for ... to locate breast abnormalities, you ... map the area you will ...
... SEAMGUARD® Staple Line Reinforcement Material is ... postoperative pulmonary air leaks and as ... This inert, biocompatible, ePTFE material requires ... easy to load and fire and ...
... Sepramesh Biosurgical Composite is designed for ... of a PPM mesh that has two ... mesh is coated with a layer of ... Biosurgery's Seprafilm® Adhesion Barrier). This coated side ...
... Hernia Repair Company, we recognize that there ... fibrous tissue in-growth between the prosthesis and ... mesh. Like all the products in Bards ... a clinically proven, versatile repair.,The Reconix Patch ...
Medicine Products: