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Regulus Provides Update on 'Road to the Clinic' Strategy and Reports First Quarter 2013 Financial Results and Recent Highlights
Date:5/14/2013

same period in 2012.

As of March 31, 2013, Regulus had $90.7 million in cash, cash equivalents and short-term investments, debt with a principal balance of $5.4 million and approximately 36 million shares of common stock outstanding.  The Company expects its current cash position to be sufficient to fund operations into 2016 and to finish 2013 with at least $60.0 million in cash, cash equivalents and short-term investments. 

Conference Call & Webcast InformationRegulus will host a conference call and webcast at 5:00 p.m. Eastern Daylight Time today for an update on the 'Road to the Clinic' Strategy and to discuss its first quarter 2013 financial results and recent highlights. A live webcast of the call will be available online at www.regulusrx.com. A replay will also be available approximately one hour after completion of the call. To access the replay, dial (855) 859-2056 (domestic) or (404) 537-3406 (international), passcode 59485223. The webcast and replay will be archived on the company's website following the call.About the 'Road to the Clinic' Strategy in 2013Launched in February 2013, the 'Road to the Clinic' Strategy outlines certain corporate goals that seek to advance our microRNA therapeutic pipeline toward the clinic this year. Specifically, Regulus set the goal of nominating two microRNA candidates for clinical development in 2013.  We announced the first candidate today as RG-101 for the treatment of HCV.  The company also expects to file its first applications with regulatory authorities in 2014, with the first being for RG-101 in early 2014.  In order to achieve these stated goals and advance our programs toward clinical development, Regulus expects to maintain its strong financial position and end 2013 with at least $60 million in cash, cash equivalents and short-term investments.

About RegulusRegulus Therapeutics Inc. (NASDAQ: RGLS) is a biopharmaceu
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