Navigation Links
Regeneron and Bayer Report Positive Results for VEGF Trap-Eye in Phase 3 Study in Central Retinal Vein Occlusion (CRVO) and in Phase 2 Study in Diabetic Macular Edema (DME)
Date:12/20/2010

, inappropriate blood vessels that can cause further vision loss and more serious complications.  Release of vascular endothelial growth factor (VEGF) contributes to increased vascular permeability in the eye and inappropriate new vessel growth.  It is believed that anti-VEGF treatment may help decrease vascular permeability and edema and prevent the inappropriate growth of new blood vessels in the retina in patients with CRVO.

About Diabetic Macular Edema (DME)DME is the most prevalent cause of moderate vision loss in patients with diabetes.  DME is a common complication of Diabetic Retinopathy (DR), a disease affecting the blood vessels of the retina.  Clinically significant DME is a leading cause of blindness in younger adults (under 50).  Clinically significant DME occurs when fluid leaks into the center of the macula, the light-sensitive part of the retina responsible for sharp, direct vision.  Fluid in the macula can cause severe vision loss or blindness.

Approximately 370,000 Americans currently suffer from clinically significant DME, with 95,000 new cases arising each year.  According to the American Diabetes Association, more than 18 million Americans currently suffer from diabetes, and many other people are at risk for developing diabetes.  With the incidence of diabetes steadily climbing, it is projected that up to 10 percent of all patients with diabetes will develop DME during their lifetime.

About VEGF Trap-EyeVEGF Trap-Eye is a fully human fusion protein, consisting of soluble VEGF receptors 1 and 2, that binds all forms of VEGF-A along with the related Placental Growth Factor (PlGF).  VEGF Trap-Eye is a specific and highly potent blocker of these growth factors.  VEGF Trap-Eye is specially purified and contains iso-osmotic buffer concentrations, allowing for injection into the eye.

Regeneron and Bayer HealthCare are collaborating on the global development of VEGF Trap
'/>"/>

SOURCE Regeneron Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Bayer and Regeneron Dose First Patient in Second Phase 3 Study for VEGF Trap-Eye in Wet Age-Related Macular Degeneration
2. Bayer and Regeneron Extend Development Program for VEGF Trap-Eye to Include Central Retinal Vein Occlusion
3. Enrollment Completed in Regeneron and Bayer HealthCare Phase 3 Studies of VEGF Trap-Eye in Neovascular Age-Related Macular Degeneration (Wet AMD)
4. Regeneron Announces Presentation at the 18th Annual Credit Suisse Healthcare Conference
5. Regeneron Reports Third Quarter 2009 Financial and Operating Results
6. Sanofi-aventis and Regeneron Expand Strategic Antibody Collaboration
7. Regeneron Announces Presentation at the Deutsche Bank 2009 Biotech Boston Confab
8. BioMed Realty Trust Signs New Lease With Regeneron Pharmaceuticals for 131,000 Square Feet at Landmark
9. Regeneron Announces Presentation at the Morgan Stanley Global Healthcare Conference
10. Regeneron Announces Presentation at the UBS Global Life Sciences Conference
11. Regeneron Announces Panel Discussion at Citis 5th Annual Biotech Day
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... April 17, 2015  Regulatory leaders in the pharmaceutical ... discussion draft called "21 st Century Cures." ... be taken up by Congress soon and if enacted ... device products are developed and marketed in ... companies have begun to consider how the proposed changes ...
(Date:4/17/2015)... , April 17, 2015  AbbVie Inc. ("AbbVie") (NYSE / ... it has extended the expiration of its exchange offer to ... Pharmacyclics, Inc. to 5 p.m., New York City ... On April 17, 2015, AbbVie also voluntarily withdrew its initial ... in order to provide the FTC with additional time to ...
(Date:4/17/2015)... Nonin Medical, a global leader in noninvasive ... Officer Steve Bucholz will retire May 1. ... role as Chief Executive Officer. In addition, Mr. Isaacson ... Operations will transition to David Noel , Chief ... been instrumental to Nonin Medical,s growth," Mr. Isaacson said. ...
Breaking Medicine Technology:21st Century Cures: A Regulatory Game-Changer for the Pharmaceutical Industry 2AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 2AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 3AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 4Nonin Medical's Philip Isaacson Expands CEO Role; President and COO Steve Bucholz to Retire May 1 2
(Date:4/19/2015)... 2015 A live auction will be held ... major hospital in Brooklyn, NY and other national consignors. Various ... lab, anesthesia, exam and much more. , The auction ... starting at 9:00am CDT each day. The equipment is at ... Park, IL 60160. Anyone can participate in the auction ...
(Date:4/19/2015)... Indiana Fiber Network, LLC (IFN), the ... major bandwidth upgrade infrastructure service to AdamsWells Internet ... Telephone Company, Inc. (DBA AdamsWells), one of IFN’s ... 10 Gigabit internet transport ring. , According ... and Marketing, AdamsWells expanded Internet bandwidth will benefit ...
(Date:4/19/2015)... Wisconsin Dells, WI (PRWEB) April 19, 2015 ... solutions designer announces that it will exhibit it’s ... Conference and Expo and the Iowa-Illinois Safety Council Professional ... Go 6350 and the TaskMate EZ are used in ... and healthcare facilities. , Built to clamp to ...
(Date:4/18/2015)... 19, 2015 The Residential Senior ... the past five years. The industry, which provides residential ... to fully care for themselves, has boomed on account ... dementia care for seniors with memory impairment. As a ... annualized rate of 4.1% to $1.9 billion over the ...
(Date:4/18/2015)... Carinsurancequotesinfo.com has released a new blog ... injuries caused by a car accident. , ... a vehicle. A policy can pay for car repairs ... should always carry appropriate coverage when they are driving. ... bought with several important riders that offer extra coverage ...
Breaking Medicine News(10 mins):Health News:Centurion to Sell Surplus Medical Equipment in Online and On-Site Auction 2Health News:AdamsWells Internet Telecom TV Expands Bandwidth via Indiana Fiber Network, LLC 2Health News:HealthPostures' TaskMate Products to be Exhibited at the Wisconsin and Iowa-Illinois Safety Conferences 2Health News:Residential Senior Care Franchises in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Residential Senior Care Franchises in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:Auto Insurance Plans Can Cover Physical Injuries Caused By An Accident! 2
... that increase the response to sweets , THURSDAY, Dec. 24 ... "munchies" -- the desire that pot smokers sometimes have to ... marijuana, is similar to substances known as endocannabinoids, which are ... of sweet foods, researchers say. , "Our taste cells may ...
... Dec. 25 Adding 30 minutes of daily physical activity ... healthier 2010, says Peter Brubaker, professor of health and exercise ... most important step toward a healthier lifestyle, Brubaker says. , ... physical activity even if you never lose a pound," he ...
... speed can improve depending on how product is designed, study ... games have been blamed for everything from promoting youth violence ... the minds of parents who planned on passing by the ... shows that playing video games can sharpen certain thinking skills, ...
... , Association looks forward to improving legislation in conference ... Barry Rand released this statement after this morning,s passage of ... members of the House of Representatives and Senate to begin ... in the New Year. , "This morning the Senate brought ...
... Bill Must Be Improved: Anti-Choice Provisions in Senate ... Must Be Affordable , WASHINGTON, Dec. 24 ... National Partnership for Women & Families: , "The Senate took ... system this morning by passing comprehensive reform that will cover ...
... generate embryonic-like cells, study finds , THURSDAY, Dec. 24 (HealthDay ... the common cold and heal wounds, but the antioxidant might ... embryonic-like stem cells, new research suggests. , The findings, ... Cell , add to previous research that showed how adult ...
Cached Medicine News:Health News:30 Minutes to Better Health in 2010 2Health News:Video Games Could Boost Certain Thinking Skills 2Health News:Video Games Could Boost Certain Thinking Skills 3Health News:AARP Thanks Senate for Passing Health Care Reform 2Health News:Senate Passage of Health Reform a Historic Milestone, National Partnership President Says 2
Quick Release Holder for the 8000 Series Sliding Microtome. A simple to use hlder for wax cassettes. Accepts standard size wax cassettes (26 x 31 x 5mm). Can be specified instead of standard vice ...
Quick Release Holder designed for the 8000 Series Microtome to hold hardboard squares....
Steel Knife with box for the Series 8000 Sliding Microtome. C-Profile, 240 x 33 x13m, 22 Degree angle, tapped to accept holder for Shandon knife sharpener....
... new SureCut M3500 Radial Microtome has a look ... and a range of functions and capabilities that ... Based on years of experience and knowledge but ... the SureCut M3500 Microtome will be the answer ...
Medicine Products: