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Regeneron Reports Fourth Quarter and Full Year 2012 Financial and Operating Results
Date:2/14/2013

ve milestone payment from Sanofi in the third quarter of 2012 in connection with FDA approval of ZALTRAP for patients with mCRC that is resistant to or has progressed following an oxaliplatin-containing regimen.

Product Revenues: Net product sales were $281 million in the fourth quarter and $858 million for the full year 2012, compared to $30 million in the fourth quarter and $45 million for the full year 2011.  The increase was due to the approval and launch of EYLEA in November 2011.  EYLEA net product sales were $276 million in the fourth quarter and $838 million for the full year 2012, compared to $25 million for both the fourth quarter and full year 2011.  ARCALYST net product sales were $5 million in both the fourth quarters of 2012 and 2011, and $20 million for both the full years 2012 and 2011.  

Research and Development (R&D) Expenses: In 2012, GAAP R&D expenses were $181 million in the fourth quarter and $626 million for the full year, compared to $129 million in the fourth quarter and $530 million for the full year 2011.  The higher R&D expenses in 2012 were principally due to increased R&D headcount and activities, primarily related to the Company's antibody collaboration with Sanofi, and higher non-cash share-based compensation expense, partly offset by lower EYLEA development costs incurred by Bayer HealthCare.  In 2012, R&D related non-cash share-based compensation expense was $18 million for the fourth quarter and $54 million for the full year, compared to $9 million in the fourth quarter and $33 million for the full year 2011.

Selling, General, and Administrative (SG&A) Expenses: In 2012, GAAP SG&A expenses were $58 million in the fourth quarter and $211 million for the full year, compared to $36 million in the fourth quarter and $117 million for the full year 2011.  The increase was primarily due to higher selling expenses in connection with commercialization of E
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SOURCE Regeneron Pharmaceuticals, Inc.
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