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Regeneron Reports Fourth Quarter and Full Year 2012 Financial and Operating Results
Date:2/14/2013

ly under review by other regulatory agencies worldwide.

Monoclonal Antibodies

  • Regeneron has eleven fully human monoclonal antibodies based on the Company's VelocImmune® technology in clinical development, including six in collaboration with Sanofi.
  • ODYSSEY, a large, global Phase 3 program with REGN727, an antibody targeting PCSK9 to reduce LDL cholesterol, was initiated in June 2012 and is currently enrolling patients.  The Company expects to report initial results from a Phase 3 ODYSSEY trial in the second half of 2013.
  • REGN668, an antibody targeting IL-4R, demonstrated positive proof of concept in allergic asthma and atopic dermatitis.  Data in atopic dermatitis will be presented at the 71st Annual Meeting of the American Academy of Dermatology in March 2013.  Data in allergic asthma will be submitted to medical conferences for presentation later in the year.
  • REGN1500, an antibody against an undisclosed target that is being developed outside of the Sanofi collaboration, entered clinical development. 
  • Fourth Quarter and Full Year 2012 Financial ResultsTotal Revenues: Total revenues were $415 million in the fourth quarter and $1.4 billion for the full year 2012, compared to $123 million in the fourth quarter and $446 million for the full year 2011.  Total revenues include collaboration revenues of $127 million in the fourth quarter and $494 million for the full year 2012, compared to $86 million in the fourth quarter and $370 million for the full year 2011.  Included in collaboration revenues in 2012 were $15 million and $10 million substantive milestone payments from Bayer HealthCare which the Company earned in the third quarter and fourth quarter of 2012, respectively, in connection with receipt of marketing and pricing approvals in Japan for EYLEA for the treatment of wet AMD.  In addition, the Company earned a $50 million substanti
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    SOURCE Regeneron Pharmaceuticals, Inc.
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