Navigation Links
Regeneron Announces FDA Acceptance of ARCALYST® (rilonacept) Supplemental Biologics License Application for Review
Date:11/22/2011

inflammatory therapeutic.

Overall, in RE-SURGE, the cumulative rate of infections was 20.1% in patients treated with ARCALYST and 19.1% in placebo patients.  Serious infections were reported in 0.5% of patients treated with ARCALYST® and 0.9% of placebo patients.  Deaths were reported for 0.3% of patients treated with ARCALYST and 0.9% of placebo patients.  The mean number of gout flares during the 16week treatment period was significantly lower in the ARCALYST 160mg treatment group when compared to placebo (0.51 and 1.73, respectively, a 71% reduction, p<0.0001). The proportion of patients with at least one gout flare was significantly lower in the ARCALYST 160mg group when compared to placebo at week 16 (25.7% [245/952] vs. 51.1% [165/323, p<0.0001].

About GoutGout is a condition that occurs when the bodily waste product, uric acid, is deposited in the joints and/or soft tissues.  In the joints, these uric acid crystals cause inflammation, which leads to pain, swelling, redness, warmth, and stiffness in the joints.  Treatment guidelines recommend that patients with elevated uric acid levels who experience multiple gout attacks each year should receive chronic uric acid-lowering therapy, such as allopurinol.  Untreated chronic gout can lead to joint and kidney damage.  Uric acid-lowering therapy can prevent the occurrence of gout attacks with long-term use and reduce the risk of organ damage.  Approximately 750,000 gout patients initiate allopurinol therapy each year.  During the first months of allopurinol therapy while uric acid blood levels are being reduced, the break up of the uric acid crystals can result in stimulation of inflammatory mediators, including interleukin-1 (IL-1), resulting in acute flares of joint pain and inflammation.  These acute flares can result in patient non-adherence to long-term uric acid-lowering therapy and resultant poor disease control.

Rationa
'/>"/>

SOURCE Regeneron Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Rockefeller University President Marc Tessier-Lavigne Elected to Regeneron Board of Directors
2. Regeneron Announces FDA Approval of EYLEA™ (aflibercept) Injection for the Treatment of Wet Age-Related Macular Degeneration
3. Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia
4. Regeneron Pharmaceuticals Announces Pricing of Offering of Convertible Senior Notes due October 1, 2016
5. Regeneron Ranked by Science Magazine as the #2 Employer in the Global Biopharmaceutical Industry
6. Regeneron Announces Clinical Presentations at ASRS 2011 Annual Meeting
7. Regeneron Reports Second Quarter 2011 Financial and Operating Results
8. Sanofi and Regeneron Report Positive Phase 2b Trial Results with Sarilumab in Rheumatoid Arthritis
9. Trading in Regeneron Common Stock Halted
10. Regeneron Reports First Quarter 2011 Financial and Operating Results
11. Regeneron Announces Presentation at the Bank of America Merrill Lynch 2011 Health Care Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... , Aug. 28, 2015  Perrigo Company plc ("Perrigo") ... has completed the acquisition of leading OTC brands from ... million. The transaction is a clear demonstration of Perrigo,s ... leading European distribution network spanning 36 countries.  ... Papa commented, "We are excited to complete this ...
(Date:8/28/2015)... LONDRES, 28 de agosto de 2015   ... su participación en el  Congreso de la ESC ... más recientes y novedosas, entre ellas HeartModel A.I. ... las personas y la tecnología con los protocolos ... guiar los tratamientos y permitir atención en el ...
(Date:8/27/2015)... , Aug. 27, 2015 DURECT Corporation ... scheduled to present at three upcoming healthcare conferences.  ... and CEO, will present at the Rodman & Renshaw ... Eastern time. The conference is being held at the ... . A live audio webcast of the presentation ...
Breaking Medicine Technology:Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 3Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 2Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 5DURECT to Participate in Upcoming Healthcare Conferences 2
... Foundation, in collaboration with Kessler Institute for Rehabilitation, announced ... exoskeleton investigational studies, which will commence October 17.  Made ... exoskeleton that enables wheelchair users to stand and walk. ... both its company name and product line on October ...
... Ill., Oct. 14, 2011 Pregis Corporation, a ... packaging products and specialty packaging solutions, announced today ... agreement to sell its Kobusch-Sengewald business unit to ... European adviser to Sun Capital Partners, Inc., for ...
Cached Medicine Technology:Kessler Foundation Identifies Six Participants to Test Ekso 2Kessler Foundation Identifies Six Participants to Test Ekso 3Kessler Foundation Identifies Six Participants to Test Ekso 4Pregis Announces Sale of Kobusch-Sengewald Business to an Affiliate of Sun European Partners 2Pregis Announces Sale of Kobusch-Sengewald Business to an Affiliate of Sun European Partners 3
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... Medical Solutions, ... 2015 Best Places to Work in Healthcare by Modern Healthcare and will ... , Now in its eighth year, the Best Places to Work in Healthcare ...
(Date:8/28/2015)... ... August 28, 2015 , ... Dr. Gregory K. Toumayan, D.C., Q.M.E., is now ... shoulder pain, hip pain, neck pain, stiffness, muscle spasms, and numbness. ... of Illinois, and then went on to earn his title of Doctor of Chiropractic ...
(Date:8/28/2015)... ... 28, 2015 , ... Northridge dentists Dr. Elyson and Dr. Assili ... patients can currently receive a one hour treatment of this teeth whitening option. ... a number of unique features that can turn teeth up to nine shades whiter. ...
(Date:8/28/2015)... ... August 28, 2015 , ... Healthpointe ... seeking to go deep sea diving. The act of recreational diving exposes ... for these reasons, it is vital that all recreational and professional divers undergo ...
(Date:8/28/2015)... , ... August 28, 2015 ... ... Inc.’s (AIS) Medicare-Medicaid Dual Eligibles Database have added comprehensive information on two ... demonstration approved for a December 2015 launch; and Idaho’s partnership to revamp ...
Breaking Medicine News(10 mins):Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 3Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 2Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 3Health News:Northridge Dentists Dr. Elyson and Dr. Assili Now Offer a Special Promotion on Zoom Teeth Whitening 2Health News:Healthpointe Now Offering Scuba Physicals 2Health News:AIS Duals Database: August Update Finds Two New Duals Programs in Rhode Island and Idaho 2
... ... , ... 17, 2010 -- SleepBetter.org, the web,s premier source for news, tips, and information on how ... to help their children settle down for a good night,s sleep. The Bedtime Stories ...
... ... milk chocolate-covered cereal snack for added flavor and crunch , ... Hicksville, NY (PRWEB) June 17, 2010 -- Whether it’s a ... JUST CEREAL , a new milk chocolate-coated cereal snack sold at Walmart in the candy ...
... costlier drugs increased after new rules took effect, study ... in Medicare payments to doctors who administer outpatient chemotherapy ... among Medicare recipients, finds a new study. , "This ... would expect, but economists often encounter this sort of ...
... ... made up of three products: Semantics.Datacenter, Semantics.Server, and Semantics.Framework. Semantics.Datacenter v 2.0 measures ... (Berlin 100M 5/25/10). , ... Brattleboro, VT (PRWEB) June 17, 2010 -- Intellidimension, Inc. a leading ...
... ... Implementation , ... Ontario (PRWEB) June 17, 2010 -- Phybridge Inc.,a leading provider of IP telephony ... from Avaya, a leading global provider of business communications applications, systems and services. ...
... ... to be “Stay-Cations” with a house boating trip at Sunset Marina and Resort. Beautiful ... by the beautiful hills of Tennessee. , ... Byrdstown, TN (PRWEB) June 17, 2010 -- Families are flocking ...
Cached Medicine News:Health News:Sleep Tips Web Site SleepBetter.org Expands The Bedtime Stories Project 2Health News:Sleep Tips Web Site SleepBetter.org Expands The Bedtime Stories Project 3Health News:Top Off Your Favorite Summer Treat with NOT JUST CEREAL&#8482; 2Health News:Top Off Your Favorite Summer Treat with NOT JUST CEREAL&#8482; 3Health News:Medicare Cuts May Have Led Docs to Prescribe More Chemo 2Health News:Intellidimension Releases New Version of Semantic Web Technologies 2Health News:Phybridge Network Solution Achieves Avaya &#8220;Compliant&#8221; Status 2Health News:Phybridge Network Solution Achieves Avaya &#8220;Compliant&#8221; Status 3Health News:Sunset Marina and Resort on Tennessee's Dale Hollow Lake Provides Affordable Houseboat Vacations for Price-Conscious Families 2
#2 TigerWire, a white suture with black spiral markings, was created specifically for arthroscopic surgeons that require superior suture visibility, easier arthroscopic orientation and motion determi...
... FiberSnare with closed loop provides an ... FiberWire loop on the tip of the ... wire, insert the stiff non-looped end retrograde ... The FiberSnare can also be used as ...
... mainstay in a urologic workup. The EasyFlo was ... an accurate, easy-to-use in-office uroflow system. EasyFlo automatically ... flow and automatically ends when a period of ... is no need to have personnel present to ...
... UroPass II Open Tip Ureteral ... benefits of the UroPass. In addition, ... helps to achieve easier stent placement ... calyx. The result is a remarkably ...
Medicine Products: