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Regenerative Medicine Markets
Date:3/25/2013

.73.3 Biomerix 3D Scaffolds 281
10.73.4 RollerCell 40 281
10.74 Tengion, Inc. 282
10.74.1 Tengion's Scientific Platform 282
10.74.2 Tengion's Pipeline 283
10.75 TiGenics NV 283
10.75.1 ChondroCelect 284
10.75.2 CX601 284
10.75.3 Cx611 285
10.75.4 Cx621 285
10.76 Tissue Genesis, Inc. 285
10.76.1 Clinical Therapies from Tissue Genesis 285
10.76.1.1 Icellator 286
10.76.1.2 Adipase 286
10.77 Thermogenesis Corp. 286
10.77.1 AXP System 286
10.77.2 MXP System 287
10.77.3 Manual Systems 287
10.77.4 Res-Q 60 BMC System 288
10.77.5 BioArchive System 288
10.78 ViaCyte, Inc. 288
10.78.1 Technology Overview 289
10.79 Vistagen Therapeutics, Inc. 289
10.79.1 Vistagen's Technology 289
10.79.2 CardioSafe 3D 290
10.79.3 LiverSafe 3D 290
10.80 Zen-Bio, Inc. 290

Appendix 1: Allogeneic vs. Autologous Stem Cell Therapy 292
Appendix 1.1: Manufacturing Process 292
Appendix 1.2: Cost Differential 293
Appendix 1.3: Donor Screening and Testing 294
Appendix 1.4: Release Testing 294
Appendix 1.5: Overall Analysis 294

INDEX OF FIGURES

Figure 2.1: Geographic Distribution of Tissue Engineering Firms in Major Markets
32
Figure 2.2: The Potential Uses of Embryonic Stem Cells 33
Figure 2.3: Progress of Cell Therapy Product Research, 2012 34
Figure 2.4: Commercially Available Cell Therapy Products, 2012 35
Figure 2.5: Disease Focus by Regenerative Medicine 39
Figure 2.6: Estimated Completion Dates for Stem Cell Based Clinical Trials
Targeting Type 1 Diabetes,
2009-2015 45
Figure 2.7: Number of Clinical Trials by Targeted Condition, 2005-2011 45
Figure 2.8: Concentration of European Cell Therapy Firms, 2012 46
Figure 2.9: European Stem Cell Platforms by Cell Source 47
Figure 2.10: Autologous vs. Allogeneic Stem Cell Therapy Firms in Europe, 2012
48
Figure 2.11: Autologous and
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