Navigation Links
Regado Biosciences Announces Publication in Circulation of Clinical Trial Results of REG1 Anticoagulation System
Date:6/5/2008

Regado's lead product candidate, REG1, is the first specific, direct-acting, antidote-controlled anticoagulant ever described. Regado is developing REG1 for use in patients suffering from acute coronary syndrome who undergo coronary revascularization procedures. These procedures, which include coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI), put patients at a high-risk for therapy-related bleeding complications. REG1 is being developed initially to increase therapeutic flexibility and improve patient outcomes in coronary revascularization procedures.

REG1 is a two-component system, consisting of an aptamer-based anticoagulant and its matched antidote. The REG1 anticoagulant component (RB006) is a single-stranded, nucleic acid aptamer. RB006 selectively and potently binds to and inhibits Factor IXa, a protein that is critical to blood coagulation. The antidote component, RB007, is a complementary nucleic acid that binds to and neutralizes RB006. The binding of RB007 to RB006 causes the predictable and rapid reversal of RB006 that allows the patient's blood to return to normal.

About Regado Biosciences

Regado Biosciences is pioneering a new therapeutic field with the discovery and development of drug:antidote systems. Regado's drug:antidote systems are designed to give physicians the ability to fine-tune the therapeutic effect desired for each patient and in each setting. A spin-out of the Department of Surgery at Duke University Medical Center, Regado was created to answer the therapeutic needs identified by its scientific founders.

The Company's proprietary platform technology enables the discovery of oligonucleotide-based drug-antidote pairs to any target protein. Regado initially is focusing its discovery and development efforts on the acute care injectable antithrombotics, a multi-billion dollar market in need of therapeutics with improved safety profiles. Potential future indications for Regado's
'/>"/>

SOURCE Regado Biosciences
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Regado Biosciences Presents Early Stage Clinical Data for REG1 Anticoagulation System at American Heart Association 2007 Scientific Sessions
2. Regado Biosciences Presents Positive Data From REG1 Anticoagulation System Phase Ic Study at American Heart Association 2007 Scientific Sessions
3. Regado Biosciences Initiates Phase IIa Clinical Study of REG1 Anticoagulation System
4. Magellan Biosciences Companies to Feature Automated Products and New Tests for MRSA at the American Society for Microbiology Meeting, Booth 743
5. Ardea Biosciences Presents Preclinical Data on RDEA119 Demonstrating Favorable Anti-Inflammatory Profile for Potential Use in Ulcerative Colitis
6. Ardea Biosciences Identifies Lead Development Candidate for Gout, RDEA594
7. Ardea Biosciences Appoints John W. Beck Chief Financial Officer, Announces Clinical Development Progress and Reports First Quarter 2008 Financial Results
8. Catalyst Biosciences Selects Drug Development Candidate in Factor VIIa Program for Hemophilia
9. Neurocrine Biosciences Reports First Quarter 2008 Results
10. Ardea Biosciences Presents Data Demonstrating Favorable Pharmacokinetics and Efficacy for Mitogen-Activated ERK Kinase (MEK) Inhibitors
11. Sangamo BioSciences Announces Presentation of Data on ZFP Therapeutic for Glioblastoma at American Association for Cancer Research (AACR) Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2015)... 27, 2015  Pharmacyclics, Inc. (NASDAQ: ... study published in the Proceedings of the ... that showed when ibrutinib (IMBRUVICA ® ) was ... suppression of tumor growth was enhanced suggesting a ... hematologic cancers and solid tumors with the combination. ...
(Date:2/27/2015)... YORK , Feb. 27, 2015 Securities ... the board of Salix Pharmaceuticals, Ltd. (NASDAQ: ... $158.00 per share. Concerned SLXP investors are encouraged to ... The investigation focuses upon the shareholder ... agreement, Salix shareholders would receive only $158.00 per share ...
(Date:2/27/2015)... 27, 2015  Boston Scientific Corporation (NYSE: ... 2015 Annual Healthcare Conference on March 10 in ... Brennan , executive vice president and chief financial officer, ... will participate in a 25-minute question and answer session ... 1:05 p.m. ET. Following a 5-minute break, a question ...
Breaking Medicine Technology:In Pre-Clinical Studies Ibrutinib Enhances Anti-tumor Activity When Combined With An Anti-PD-L1 Antibody 2In Pre-Clinical Studies Ibrutinib Enhances Anti-tumor Activity When Combined With An Anti-PD-L1 Antibody 3In Pre-Clinical Studies Ibrutinib Enhances Anti-tumor Activity When Combined With An Anti-PD-L1 Antibody 4In Pre-Clinical Studies Ibrutinib Enhances Anti-tumor Activity When Combined With An Anti-PD-L1 Antibody 5In Pre-Clinical Studies Ibrutinib Enhances Anti-tumor Activity When Combined With An Anti-PD-L1 Antibody 6In Pre-Clinical Studies Ibrutinib Enhances Anti-tumor Activity When Combined With An Anti-PD-L1 Antibody 7In Pre-Clinical Studies Ibrutinib Enhances Anti-tumor Activity When Combined With An Anti-PD-L1 Antibody 8In Pre-Clinical Studies Ibrutinib Enhances Anti-tumor Activity When Combined With An Anti-PD-L1 Antibody 9Boston Scientific to Participate in the Barclays 2015 Annual Healthcare Conference 2
(Date:3/1/2015)... 2015 Comparing a new source of ... the Quotes Pros portal this year. A broad range ... rates that are being supplied through the finder at ... and prices available for each policy is now provided ... system user will first be asked to present their ...
(Date:3/1/2015)... Ticket Down is a reputable source for authentic ... Deadheads have been anxiously anticipating this blockbuster weekend ever ... formed 50 years ago back in the 60s in Palo ... untimely death of Jerry Garcia in 1995. This beloved ... rock, bluegrass, folk, space rock and country to become an ...
(Date:3/1/2015)... 2015 “ The Barrel Mill ” was ... which takes a look at the latest and coolest technology ... of NewsWatch and a technology expert, conducted the review and ... to drinks. , According to Home Distillation of Alcohol, it's ... Well, there’s a pretty cool product that’ll help anyone achieve ...
(Date:2/28/2015)... In recent years Medical Marijuana has continuously ... as a way for them to expand their patient base ... medicine. Since the FDA still lists Cannabis as a Schedule ... licensed physicians that can help guide them when recommending ... in Santa Cruz, CA is a leader in the ...
(Date:2/28/2015)... With their commitment to achieving physical results ... exercise to their already robust library of oblique exercises. ... known as, is often performed on a stationary piece ... a relatively safe manner and can be performed by ... description of “Rope Pulls” is located in the oblique ...
Breaking Medicine News(10 mins):Health News:United Auto Insurance Rates Now Quoted at Consumer Insurance Portal Online 2Health News:Grateful Dead Tickets at Soldier Field in Chicago: Ticket Down Slashes Grateful Dead Ticket Prices in Chicago at Soldier Field for 4th of July Weekend Celebration 2Health News:An Oak Infusion Spiral was Featured on NewsWatch Television on January 30, 2015 2Health News:Reputable Cannabis Doctor In Santa Cruz and Monterey Joins the Medical Cannabis Network 2
... , ... ... ... ...
... ... ... ... ...
... ... ... ... ...
... , ... ... ... ...
... ... of the First EcoAdvisor to Achieve EcoDirector Level With Their Business. , ... Midland (PRWEB) February 24, 2010 ... the highest level of achievement, EcoDirector status. Michelle and Kris Harvey reached this level ...
... , ... ... ... ...
Cached Medicine News:Health News:Jamba Juice Unveils All Fruit Smoothie School Lunch Program 2Health News:Jamba Juice Unveils All Fruit Smoothie School Lunch Program 3Health News:Jamba Juice Unveils All Fruit Smoothie School Lunch Program 4Health News:Jamba Juice Unveils All Fruit Smoothie School Lunch Program 5Health News:Wounded Soldier Who Received Historic Cell Transplant Gets Standing Ovation at Diabetes Research Institute Benefit 2Health News:Wounded Soldier Who Received Historic Cell Transplant Gets Standing Ovation at Diabetes Research Institute Benefit 3Health News:Wounded Soldier Who Received Historic Cell Transplant Gets Standing Ovation at Diabetes Research Institute Benefit 4Health News:Wounded Soldier Who Received Historic Cell Transplant Gets Standing Ovation at Diabetes Research Institute Benefit 5Health News:Wounded Soldier Who Received Historic Cell Transplant Gets Standing Ovation at Diabetes Research Institute Benefit 6Health News:Stevens Hospital One Step Closer to Affiliation with Swedish 2Health News:Stevens Hospital One Step Closer to Affiliation with Swedish 3Health News:Stevens Hospital One Step Closer to Affiliation with Swedish 4Health News:Stevens Hospital One Step Closer to Affiliation with Swedish 5Health News:Stevens Hospital One Step Closer to Affiliation with Swedish 6Health News:Stevens Hospital One Step Closer to Affiliation with Swedish 7Health News:Stevens Hospital One Step Closer to Affiliation with Swedish 8Health News:Stroke Conference Daily News Summary 2Health News:Stroke Conference Daily News Summary 3Health News:Stroke Conference Daily News Summary 4Health News:Stroke Conference Daily News Summary 5Health News:Stroke Conference Daily News Summary 6Health News:OnlyGreen Celebrates First EcoDirector 2Health News:ANF Group's Tour de Broward Raises Money for Joe DiMaggio Children's Hospital 2Health News:ANF Group's Tour de Broward Raises Money for Joe DiMaggio Children's Hospital 3Health News:ANF Group's Tour de Broward Raises Money for Joe DiMaggio Children's Hospital 4
Each handle is designed to fit a specific trephine size....
Reusable, stainless steel trephine with handle....
Reusable, stainless steel trephine with handle....
Each handle is designed to fit a specific trephine size. For use in performing free-hand uniform donor buttons....
Medicine Products: