Navigation Links
Receptos to Deliver Scientific Presentation at Digestive Disease Week 2012 about the Therapeutic Role of RPC1063 in Inflammatory Bowel Disease

SAN DIEGO, May 18, 2012 /PRNewswire/ -- Receptos Inc. today announced that company personnel will deliver a scientific podium presentation about RPC1063 at the Digestive Disease Week (DDW) annual meeting at 9 a.m. PDT on Sunday, May 20, 2012 at the San Diego Convention Center in San Diego, California. DDW attracts thousands of physicians, researchers, and academics from around the world to share the latest research in gastrointestinal health topics, for which DDW is the premier scientific conference. Based on an abstract entitled "A small molecule S1P1 receptor agonist with significant efficacy in animal models of inflammatory bowel disease (IBD)," Receptos scientific personnel will discuss positive preclinical data with RPC1063 in two distinct in vivo models of IBD.

"Based on exciting data from these preclinical studies, as well as data from a recently completed Phase 1 clinical safety study, Receptos will initiate a Phase 2 clinical trial with RPC1063 in 2012 in inflammatory bowel disease," said Faheem Hasnain, President and Chief Executive Officer of Receptos. "The acceptance of these preclinical efficacy data for presentation at DDW underscores the need for efficacious oral treatments for the therapeutic treatment of IBD and the excitement on the part of scientific and clinical investigators to explore the novel profile of RPC1063 in patients suffering from this debilitating disease."

About RPC1063 and S1P1 Agonists
RPC1063 is a novel, differentiated sphingosine 1-phosphate 1 receptor (S1P1) selective agonist exhibiting picomolar potency that is effective in rodent models of both multiple sclerosis (MS) and inflammatory bowel disease (IBD), and possesses an excellent safety profile in non-clinical toxicology studies. Receptos has completed a Phase 1 clinical safety study with RPC1063 under a US IND that supports the desired differentiation profile and establishes justification for initiation of MS and IBD clinical efficacy trials in 2012. S1P1 is a G protein-coupled receptor (GPCR) that binds the lipid signaling molecule sphingosine 1-phosphate (S1P). S1P is a circulating lipid that binds to five GPCRs termed S1P1-5. S1P1 selectively regulates physiological functions in the immune and cardiovascular systems, including immune cell trafficking and the maintenance of endothelial integrity. In autoimmune disorders, S1P1 agonism works by selectively sequestering circulating lymphocytes, blunting the underlying cause of disease.

About Receptos
Receptos is a biopharmaceutical company developing autoimmune therapeutic candidates through information‐driven drug discovery, including GPCR structure determination. The company's lead program, RPC1063, is a best‐in‐class S1P1 small molecule agonist candidate for autoimmune indications. The S1P1 program is supported by the company's proprietary high resolution protein crystal structure of the S1P1 receptor. Receptos has established partnerships for its GPCR structure determination technology platform with Eli Lilly, Ono Pharmaceutical and Janssen Pharmaceuticals, Inc. For more information visit

Media and Investor Contacts:
Russo Partners
Ian Stone or David Schull (media)
(619) 308-6541 or (212) 845-4271

Cindy McGee (investors)
(619) 308-6538

SOURCE Receptos Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Receptos Achieves Milestone Under License of G-Protein Coupled Receptor Crystal Structure Determination Technology
2. Ceregene Parkinsons Disease Study Demonstrates Long-term Neurturin Expression and Enhanced Dopamine Activity 4 Years Following Delivery of CERE-120 (AAV2-neurturin)
3. AXIOS™ Stent and Delivery System Study Demonstrates Successful Treatment of Pancreatic Pseudocysts and Acute Cholecystitis
4. Shire Delivers Strong First Quarter Performance and Reiterates its Expectation of Good Full Year Earnings Growth
5. West Physics Consulting Teams with Mirion Technologies Dosimetry Services Division to Deliver Radiation Detection Services
6. Sustained Growth Forecast for Medical Devices and Drug Delivery Markets According to New Market Research Available from Global Information Inc.
7. VICAMs New Fumo-V Strip Tests Delivers Accurate Detection of Fumonisin Mycotoxins in Minutes
8. FDA Clears Expanded Compatibility for INOMAX® Drug-Delivery Systems
9. BioDelivery Sciences Provides Business Review and Update in Conjunction with Filing of its Annual Report
10. Medical Device Study Delivers Marketing Budget and Staffing Metrics to Promote Efficient Use of Resources
11. Delcath Announces Agreement With Institut Gustave Roussy for Launch of Hepatic CHEMOSAT Delivery System in France
Post Your Comments:
(Date:11/24/2015)... iRhythm Technologies, Inc. , a leading digital health care solutions ... participate in the 27th Annual Piper Jaffray Healthcare Conference at The ... . Kevin King , Chief Executive Officer of iRhythm, ... ET. --> --> About ... . --> iRhythm is a privately held digital ...
(Date:11/24/2015)... , Nov. 24, 2015 Teledyne DALSA ... X-Ray image sensing technology, will introduce its CMOS X-Ray ... Exhibition , November 29 to December 3, at McCormick Place ... dynamic detectors for diagnostic and interventional imaging will be on ... Xineos family of advanced CMOS X-Ray detectors is the ...
(Date:11/24/2015)... The uptake of recently approved and pipeline premium products for Type 1 ... 2021, says GBI Research . --> ... Diabetes Mellitus (T1DM), will be a key driver of market growth to ... The uptake of recently approved and pipeline premium products for Type ... to 2021, says GBI Research . ...
Breaking Medicine Technology:
(Date:11/24/2015)... ... November 24, 2015 , ... Dehydration, defined as a loss of body water ... the hot sun, and heat stroke and death will quickly follow. A normal human ... Kleyne. Every cell, system and structure requires water to function properly. Kleyne, who believes ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... the only authorized OSHA Training Institute Education Center in Northern California, is calling ... holiday season’s major sales events. As the volume of sales and shoppers ...
(Date:11/24/2015)... ... 2015 , ... Add a fresh touch to this year’s holiday festivities with ... bring long-lasting style and cheer to any space. , Holiday plants are more than ... on giving all year long. , “Holiday plants make a room come alive,” says ...
(Date:11/24/2015)... ... November 24, 2015 , ... Take the audience on a journey with TransFrame Cloud ... through a cloud of images without ever setting a single keyframe in Final Cut Pro ... Then use the controls to change the angle and depth of field to create a ...
(Date:11/24/2015)... ... November 24, 2015 , ... The national nonprofit, United Breast ... scheduled for released during the Green Bay Packers vs the Chicago Bears Thanksgiving ... UBCF is honored to be a part of this event, increasing awareness of ...
Breaking Medicine News(10 mins):