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Rare Disease Therapeutics, Inc. Selects Accredo Health Group to Distribute Anascorp® for the Treatment of Centruroides Scorpion Sting Envenomation
Date:9/13/2011

b>Anascorp®, an equine-derived antivenom, is the first of a series of antivenoms in the Rare Disease Therapeutics, Inc. pipeline. Anascorp®, an F(ab')2  antibody is used for the treatment of patients with clinical signs of scorpion envenomation from the Centruroides sculpturatus scorpion. Centruroides sculpturatus is the only clinically important scorpion species with vertebrate neurotoxins whose natural range includes the United States.

About Centruroides Scorpion Sting Envenomation

The U.S. is home to at least 40 species, most are found in the southern and western states. Stings from any of these may cause local pain and swelling and don't usually warrant medical treatment. However, there is one species in the U.S. that is regarded as medically important; this is the Centruroides sculpturatus. Patients stung by the Centruroides scorpion experience immediate burning and stinging sensation at the sting site. Following the pain Centruroides scorpion envenomation produces a pattern of neurotoxicity with a spectrum of severity ranging from the trivial to life threatening. Severe envenomation, more common in small children, may involve loss of muscle control, roving or abnormal eye movements, slurred speech, respiratory distress, excessive salivation, frothing at the mouth and vomiting.  Anascorp is the only FDA-approved therapy for these envenomations.  

The most common adverse reactions observed in less than two percent of patients in the clinical studies fro Anascorp were:  vomiting, pyrexia, rash, nausea, and pruritus.  Server hypersensitivity reactions, including anaphylaxis, are possible with Anascorp.  Delayed allergic reactions (serum sickness) may occur following treatment with Anascorp.  Anascorp is made from equine plasma and may contain infectious agents, e.g., viruses.  Loc
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SOURCE Medco Health Solutions, Inc.
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