Navigation Links
Raptor Pharmaceuticals Corp. Initiates Phase IIa Clinical Study for Convivia(TM)
Date:4/21/2008

Patient Dosing Underway in Company's First Clinical Program

NOVATO, Calif., April 21 /PRNewswire-FirstCall/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced that its clinical development subsidiary, Bennu Pharmaceuticals Inc. ("Bennu"), has initiated the Company's first clinical-stage program after dosing the first cohort in a Phase IIa study of oral 4-methylpyrazole ("4-MP") in subjects with ALDH2 deficiency, or ethanol intolerance, as the initial development stage of its Convivia(TM) program. Convivia(TM) is Bennu's proprietary, oral formulation of 4-MP designed to reduce peak systemic acetaldehyde levels in ALDH2 deficient persons following alcohol consumption.

(Logo: http://www.newscom.com/cgi-bin/prnh/20071022/NYM074LOGO )

ALDH2 deficiency, sometimes referred to as "Asian flushing syndrome," is an inherited metabolic disorder affecting 40% to 50% of East Asian populations, impairing the activity of the liver enzyme aldehyde dehydrogenase ("ALDH2"). When people with ALDH2 deficiency drink alcoholic beverages, there is an accumulation of acetaldehyde, a carcinogenic intermediate in the metabolism of ethanol, in blood and tissues. Published retrospective studies have observed a significant correlation between recurrent drinkers with ALDH2 deficiency and an increase in risk for digestive tract cancers, liver diseases, late-onset Alzheimer's disease and other serious health disorders. In addition to the long-term health risks, elevated acetaldehyde levels produce acute symptoms, including facial flushing, tachycardia (rapid heart rate), headache, nausea and dizziness.

Although ALDH2 deficient people suffer from unpleasant reactions and face long-term health risks, a substantial proportion of them are recurring drinkers of alcoholic beverages. Currently there are no approved treatments for AL
'/>"/>

SOURCE Raptor Pharmaceuticals Corp.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. Raptor Pharmaceuticals Provides Update of Product Programs
2. Shareholder Class Action Filed Against Vertex Pharmaceuticals Incorporated by the Law Firm of Schiffrin Barroway Topaz & Kessler, LLP
3. Anadys Pharmaceuticals Presents Data on ANA598, a Non-Nucleoside Inhibitor of the HCV Polymerase, at the 21st International Conference on Antiviral Research
4. Alseres Pharmaceuticals Expands Sites for the First Stage of the ALTROPANE(R) Phase III Clinical Trial Program
5. Celator(R) Pharmaceuticals Successfully Uses Nanoparticles to Administer Hydrophobic Drug Combinations
6. Sunesis Pharmaceuticals Reports Data from Nonclinical Studies of SNS-032 at the Annual Meeting of the American Association for Cancer Research
7. Rib-X Pharmaceuticals Renews Collaborative Agreement with the Medical Research Council
8. Poniard Pharmaceuticals Oral Picoplatin Demonstrates Positive Bioavailability in Ongoing Phase 1 Trial
9. Antipodean Pharmaceuticals Announces Completion of Phase 2 Study of Lead Compound MitoQ(R)
10. Sunesis Pharmaceuticals to Present Non-Clinical Data at the Annual Meeting of the American Association for Cancer Research
11. Poniard Pharmaceuticals Announces Presentation of Clinical Data From Picoplatin Phase 2 Small Cell Lung Cancer Trial to be Presented at 1st IASLC-ESMO European Lung Cancer Conference

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/6/2009)... NuVasive, Inc. (Nasdaq: ...oping products for minimally disruptive surgical t...ntment of Michael J. Lambert as Executive Vice Pre...mber 9, 2009. The Company also announced several ...chael will be an excellent complement to the NuVas...
(Date:11/6/2009)..., Nov. 6 With his proposed health ...is sights on cutting name-brand prescription drug ... into the "Part D" coverage gap, universally known...e potential cost-cutting and feel it,s a promising... powerful lobbyists want a revised program that co...
(Date:11/6/2009)...RNewswire-FirstCall/ -- Cyberonics, Inc. (Nasdaq: ...rt financial results for the second quarter ended ...0, 2010 on Wednesday, November 18, 2009 at 5:00 PM...to discuss those results on Thursday, November 19,...ond Quarter Results Conference Call Instructions ...
Breaking Medicine Technology:NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 2NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 3NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 4NuVasive Appoints New Chief Financial Officer and Announces Additional Management Updates 5Obama Healthcare Reforms Fall Short, but Betterthanmedicare.com Closes the 'Donut Hole' 2Obama Healthcare Reforms Fall Short, but Betterthanmedicare.com Closes the 'Donut Hole' 3Cyberonics Announces Conference Call to Discuss Fiscal Year 2010 Second Quarter Financial Results 2Implanet Using IBM Software to Protect Patients in the Event of Medical Device Recalls 56057 1Implanet Using IBM Software to Protect Patients in the Event of Medical Device Recalls 56057 2Implanet Using IBM Software to Protect Patients in the Event of Medical Device Recalls 56057 3Stater Bros Helps Customers Fight the Flu 56055 1Stater Bros Helps Customers Fight the Flu 56055 2Lead Levels in Many Lipsticks Higher Than Reported 56053 1Lead Levels in Many Lipsticks Higher Than Reported 56053 2Lead Levels in Many Lipsticks Higher Than Reported 56053 3
...widely used as the gold standard for prostate canc...s in recent diagnostic science, a recent study at ...s by other researchers have now put the utility of...PSA era is over in the United States, said Thomas ...f the study published in the October 2004 issue of...
... analog and digital television sets, so, too, do p...ween analog and digital mammography units, with th... around the country., ,As of late 2003, the U....four digital mammography units for clinical usethe...ystems, approved in January 2000 and manufactured ...
Other Medicine Technology:PSA TestingHow Much is Too Much? 2PSA TestingHow Much is Too Much? 3Digital vs. Analog Mammography 2Digital vs. Analog Mammography 3Digital vs. Analog Mammography 4
(Date:11/8/2009)...ssage of Health Care Reform Bill ,, Critical ...erage for all Americans ,, HARRISBURG, Penn., ... Last night the United States House of Representa...on that would strengthen Medicare for seniors and ...ces millions of Americans out of affordable health...
(Date:11/8/2009)...W Academy of Health holds open house at Victoria c...us) November 8, 2009 -- UCW Academy of Health invi...lumbia’s health care industry to attend thei..., 2009. , ,UCW Academy of Health, which offers di...d social services, designs its programs to meet th...
(Date:11/8/2009)...ing Taxes Nail Nation,s Job Creators ,, WASHING... to U.S. House passage of the health care bill (H....uncil (SBE Council) president & CEO Karen Kerr...no mistake, those voting for H.R. 3962 voted to bu...nd crushing taxes and penalties. Even in the best ...
(Date:11/8/2009)...Newswire-USNewswire/ -- Tonight the House of Repre...merica Act, landmark health reform legislation tha..., affordable, stable and secure health care covera...the insurance industry,s worst practices, would ex...deficit by $104 billion over ten years. Groups rep...
(Date:11/8/2009)... Global Solutions is pleased to announce that it h...l effort for ReSound who recently received an awar...act. The award includes not only the Veterans Admi... other federal agencies. , ...al Solutions is pleased to announce that it has be...
Breaking Medicine News(10 mins):Health News:AARP Pennsylvania Key Vote News Alert 2Health News:AARP Pennsylvania Key Vote News Alert 3Health News:AARP Pennsylvania Key Vote News Alert 4Health News:College Invites Public to Explore Career Options in Health Care 2Health News:Democratic National Committee Chairman Tim Kaine Issues Statement Praising the House of Representative's Historic Vote to Pass Health Insurance Reform 2Health News:Democratic National Committee Chairman Tim Kaine Issues Statement Praising the House of Representative's Historic Vote to Pass Health Insurance Reform 3Health News:3D Global Solutions Selected to Program Manage GN ReSound/VA Digital Hearing Aid Contract 2Health News:3D Global Solutions Selected to Program Manage GN ReSound/VA Digital Hearing Aid Contract 3
...he company which markets Aricept with Pfizer Inc. ...at mild to moderate Alzheimer's disease //, but at...ular dementia, the second most common form of deme...ld at Japan's Eisai Co. There were no deaths a...
... chickens in Afghanistan would have to wait until ...rotective clothing by the U.S. forces//, according...Department of Afghanistan. Bird flu infectio...d be implemented with immediate effect, the poor s...
...Friday night’s attack on 30 junior doctors by the ...o medical apathy// , has instigated 200 junior doc...trike work. The chief minister of Kolkata ha...ds would be positively looked into. But the doctor...
...amine usage also known as ice has resulted in incr...arning of the increasing number of cases// and the... Statistics show that about one in four ice addic...ve surpassed the heroin addicts in Australia. ...
...artment of New South Wales has conducted a study w...erious impact on the user's physical health// . ... health conditions. Cannabis abuse can lead to car...ales Health Minister John Hatzistergos will open t...
...se of bird flu in Maharashtra has ruffled up chick...rm, chicken prices which were stabilizing// , have...n Maharashtra during the last few days. Th... by bird-flu. The losses to the poultry industry h...
Other Medicine News:Health News:High Demand For Protective Suit in Afghan: Culling Would Have To Wait 2
...eference laboratory and a worldwide leader in inno...ffers an extensive test menu of highly complex and...hology. Owned by the University of Utah, ARUP Labo...tion's university teaching hospitals and children'...
...eference laboratory and a worldwide leader in inno...ffers an extensive test menu of highly complex and...hology. Owned by the University of Utah, ARUP Labo...tion's university teaching hospitals and children'...
...eference laboratory and a worldwide leader in inno...ffers an extensive test menu of highly complex and...hology. Owned by the University of Utah, ARUP Labo...tion's university teaching hospitals and children'...
...eference laboratory and a worldwide leader in inno...ffers an extensive test menu of highly complex and...hology. Owned by the University of Utah, ARUP Labo...tion's university teaching hospitals and children'...
Medicine Products: