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Rapid and Long-term Clinical Responses Observed in Rheumatoid Arthritis Patients Taking Cimzia® (certolizumab pegol), According to Data Being Highlighted During ACR Meeting
Date:11/5/2010

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  • 1806 - Wednesday, November 10, 2010, 9:00 am
  • Halls B1 & B2, APS - ACR/ARHP Poster Session C

  • Safety, Efficacy, and Sustained Improvements in Household Productivity and Daily Activities with Certolizumab Pegol (CZP) Monotherapy Over 2 Years in Patients with Active Rheumatoid Arthritis (RA)
  • There was no evidence of increased incidence of adverse events with longer-term exposure to CZP (400mg) monotherapy every four weeks.  Additionally, sustained improvement in clinical signs and symptoms, home productivity and ability to engage in family/social/leisure activities over two years was seen with CZP monotherapy.  For full study information, please see: http://www.abstracts2view.com/acr/titleindex.php?num=S
  • 1832 - Wednesday, November 10, 2010, 9:00 am
  • Halls B1 & B2, APS - ACR/ARHP Poster Session C

  • The Impact of Rheumatoid Arthritis (RA) on Women: Focus on Pain, Productivity and Relationships
  • Self-reported global online assessments indicated the majority of female RA patients experienced pain despite taking pain relief medication.  RA has a negative impact on employment and causes patients to feel isolated, negatively affecting intimate relationships.  For full study information, please see: http://www.abstracts2view.com/acr/titleindex.php?num=T&page=3
  • 1063 - Tuesday, November 9, 2010, 9:00 am
  • Halls B1 & B2, APS - ACR/ARHP Poster Session B

  • Effect of the PEG Component of Certolizumab Pegol on Calcium Flux in Cellular Systems
  • The PEG component of CZP inhibits calcium flux in monocytes and mast cells at a concentration relevant at the site of injection.  This inhibition of calcium flux could, therefore, explain the low levels of injection
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