Navigation Links
RainDrop System Unlocks Power of Trovagene's Urine-Based Mutation Detection Technology

SAN DIEGO and BILLERICA, Mass., July 29, 2013 /PRNewswire/ -- Trovagene, Inc. (NASDAQ: TROV) and RainDance Technologies announced today that Trovagene has adopted RainDance's RainDropTM Digital PCR System for research and development, and for eventual use in the Trovagene CLIA laboratory.  Trovagene has also announced successful development of a cell-free DNA mutation assay leveraging the RainDrop platform.


"Trovagene's DNA isolation and assay development is at the forefront of non-invasive, cell-free cancer mutation detection and monitoring," said Roopom Banerjee, president and CEO of RainDance.  "Utilizing our RainDrop Digital PCR System, they have addressed a critical need by enabling the use of a non-invasive, systemic specimen.  This technology platform allows better assessment of tumor dynamics within an individual sample."

The automated RainDrop System allows for a hundred-fold increase in the amount of DNA that can be analyzed for cancer mutation detection, increasing sensitivity and the ability to find rare mutations.  It can analyze up to 10 million pico-liter sized droplets in a single assay, vastly improving the probability that low-level mutations will be detected. RainDance's digital PCR approach also enables quantification of the relative amounts of mutated DNA in a sample.

Understanding the genomic changes that define a patient's tumor can lead to clinically actionable information before, during and after therapy.  The ability to non-invasively detect and monitor oncogenic mutations and genomic variations, as well as markers for resistance, may improve the overall management of cancer and lead to improved outcomes.

"Trovagene's goal is to help improve detection and monitoring of cancer patients undergoing treatment, particularly those with metastatic cancers," stated Mark Erlander, chief scientific officer of Trovagene.  "Analyzing the large amounts of DNA present in urine requires a platform capable of handling hundreds of thousands, if not millions, of reactions. The RainDrop System is ideally suited for this task and enables Trovagene technology to be even more sensitive." 

Trovagene evaluated several platforms before purchasing RainDance's RainDrop Digital PCR System.  "The high level of sensitivity and workflow improvements made it a clear, cost-effective choice for detecting and quantifying singular oncogene mutations from cell-free DNA," said Erlander.

About Trovagene, Inc.
Headquartered in San Diego, California, Trovagene is leveraging its patented technology for the detection of cell-free DNA and RNA, short nucleic acid fragments, originating from normal and diseased cell death that can be isolated and detected from urine. Trovagene has a strong intellectual property asset as it relates to cell-free DNA and RNA testing in urine. It has U.S. and European patent applications and issued patents that cover testing for HPV and other infectious diseases, cancer, transplantation, prenatal and genetic testing.

Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. These statements may be identified by the use of forward-looking words such as "anticipate," "believe," "forecast," "estimated" and "intend," among others. These forward-looking statements are based on Trovagene's current expectations and actual results could differ materially. There are a number of factors that could cause actual events to differ materially from those indicated by such forward-looking statements. These factors include, but are not limited to, substantial competition; our ability to continue as a going concern; our need for additional financing; uncertainties of patent protection and litigation; uncertainties of government or fourth party payer reimbursement; limited sales and marketing efforts and dependence upon fourth parties; and risks related to failure to obtain FDA clearances or approvals and noncompliance with FDA regulations. As with any medical diagnostic tests under development, there are significant risks in the development, regulatory approval and commercialization of new products. There are no guarantees that future clinical trials discussed in this press release will be completed or successful or that any product will receive regulatory approval for any indication or prove to be commercially successful. Trovagene does not undertake an obligation to update or revise any forward-looking statement.  Investors should read the risk factors set forth in Trovagene's Form 10-K for the year ended December 31, 2012 and other periodic reports filed with the Securities and Exchange Commission.

About RainDance Technologies
RainDance Technologies is a leading life sciences company developing innovative products that enable more accurate, reliable, cost-effective and early detection of disease and predisposition risk in order to improve human healthcare. Today, RainDance is focused on better healthcare outcomes and lowering costs for the research, diagnosis and treatment of cancers and inherited diseases. The company's innovative RainStorm™ digital droplet technology powers next-generation sequencing and genetic testing systems that deliver dramatically superior performance, cost, interpretability, and ease of use. RainDance systems are used routinely in major academic research institutions, clinical genetics laboratories,  and hospitals around the world. Based in Billerica, Massachusetts, the company supports customers through its international sales and service operations as well as a global network of distributors and commercial service providers. For more information, please visit

The RainDrop System is for Research Use Only; not for use in diagnostic procedures.

RainDance Technologies, the RainDance Technologies logo, RainDrop and RainStorm are trademarks of RainDance Technologies, Inc. All other brands may be trademarks of their respective holders.Contacts:Trovagene, Inc.

RainDance Technologies, Inc.Amy Caterina

Colin SanfordInvestor Relations

Director, Corporate Communications858-952-7593

SOURCE Trovagene, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. New Blood Clot Removal System Successfully Restores Blood Flow
2. Varian Medical Systems Reports Results for Third Quarter of Fiscal Year 2013
3. Odense Universitetshospital tilfører kræftpatienters stereotaktiske strålebehandling næsten tre gange hurtigere med Elektas Versa HD-system
4. One of the Nations 50 Best Hospitals Converts to Hylands OnBase for Integrated Scanning System Across the Enterprise
6. The Financial Impact of Obesity in Brazil and Mexicos Healthcare Systems is Driving Partial Coverage of Obesity Drugs in Formularies at the State, Municipal and Hospital Levels
7. HemoShear Announces Advancement of Predictive Drug Safety Systems
8. Grifols Implements Its First Automated Inventory Management Carousel System for Investigational Pharmacies at Emory University
9. Todays Research: Delcath Systems, Astex Pharma, BioMarin Pharma, and Akorn
10. McCann Health and dacadoo ag Form Global Strategic Partnership To Expand Mobile Health & Fitness Tracking System
11. Global Holter Monitoring Systems Industry
Post Your Comments:
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Surface Marker Testing Market: Supplier Shares, ... their offering.  --> ... the  "2016 Future Horizons and Growth ...
(Date:11/25/2015)... , Nov. 25, 2015  Linden Care, LLC, a ... treatment outcomes for patients suffering from chronic pain, said ... a Temporary Restraining Order (TRO) enjoining Express Scripts from ... companies. --> --> ... of its legal options. --> ...
(Date:11/25/2015)... , November 25, 2015 ... KTOV ) (TASE: KTOV), a biopharmaceutical company focused on ... of various clinical conditions, today announced the closing of ... Depository Shares ( ADSs ), each representing 20 ordinary ... to 3,158,900 ADSs. The ADSs and warrants were issued ...
Breaking Medicine Technology:
(Date:11/25/2015)... ... November 25, 2015 , ... As part of a ... ™ attracts volunteers together who want to combine talents and resources to help ... in the process. The non-profit launched its first major fundraiser on November 6, ...
(Date:11/25/2015)... Cokato, MN (PRWEB) , ... November 25, 2015 , ... ... Thanksgiving through Christmas Eve on several models of traditional and far-infrared saunas. ... . Nordic Spruce is the most traditional Finnish sauna wood, and Finnleo uses only ...
(Date:11/25/2015)... ... 2015 , ... TyloHelo Inc , North America’s largest ... accessories help improve the bather experience in the sauna, and the accessories selected ... purist looking for simplicity in design to accessories that encourage a greater expression ...
(Date:11/25/2015)... , ... November 26, 2015 , ... ... Commission (AUC), European Union (EU), ANDI Pan African Centres of Excellence, and public ... in Nairobi (UNON) for the opening of the 5th African Network for Drugs ...
(Date:11/25/2015)... ... 2015 , ... For the first time, Vitalalert is donating half of its ... The partnership between the two groups began in 2014 with Vitalalert pledging a portion ... International was founded in 1954 and is an international Christian-based health organization whose mission ...
Breaking Medicine News(10 mins):