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RNL BIO Co. Ltd. stellt IND-Antrag, um klinische Phase-II-Studie des RNL-JointStem gegen Arthrose in den Vereinigten Staaten einzuleiten
Date:5/3/2013

rging, ist einer der größten Vorteile in der Tatsache zu sehen, dass das Produkt im Gegensatz zu vielen anderen invasiven Eingriffen, die derzeit zur Behandlung von AD eingesetzt werden, nur ein einziges Mal injiziert werden muss. „Die Behandlung dieser schmerzvollen chronischen Erkrankung sollte den Schmerz lindern und nicht verstärken", so Dr. Ra. „Wir hoffen nachzuweisen, dass RNL-JointStem wirksam zur Knorpelregeneration, Schmerzlinderung und Verbesserung der Gelenkfunktion von AD-Patienten beiträgt, und hoffen auf eine angemessen zeitnahe Marktzulassung."

Im Zuge der klinischen Studie wird RNL-JointStem mit bestehenden Verfahrensweisen auf Basis von Hyaluronsäure (HA) verglichen. Die Patientengruppe wird bei dieser klinischen Studie neben Patienten mit Arthrose-Befund auch weitere Patienten umfassen, deren Ärzte der Ansicht sind, dass sie die entsprechenden Teilnahmevoraussetzungen erfüllen. Der Zielmarkt für RNL-JointStem sind Patienten im Alter von unter 60 Jahren, für die derzeit keine wirksame Therapieoption besteht.

Informationen zu Arthrose

Die degenerative Arthritis ist die häufigste Form der Arthritis. Schätzungen zufolge leiden 26,9 Millionen Amerikaner ab einem Alter von 25 Jahren an degenerativer Arthritis bestimmter Gelenke. In älteren Bevölkerungsschichten ist der prozentuale Anteil des Krankheitsbefalls entsprechend höher. Zu den klinischen Manifestationen der Krankheit zählen Gelenkschmerz und Bewegungsbeeinträchtigung. Überdies ist das umliegende Gewebe häufig von lokalen Entzündungen befallen. Die Krankheitsursache der degenerativen Arthritis ist nicht vollständig erforscht. Verletzungen, Alter und die genetische Veranlagung gelten jedoch als Risikofaktoren.

Die degenerative Arthritis ist eine Krankheit, die progre
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SOURCE RNL BIO
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