Navigation Links
RECOVER Analyses Highlighted Need to Address Motor, Sleep and Other Non-Motor Symptoms of Parkinson's Disease
Date:4/13/2011

or symptoms, as measured by UPDRS III, and non-motor symptoms, as measured by PDNMS scores at baseline (r=0.35, p<0.0001), and end of maintenance (EoM) treatment (r=0.38, p<0.0001), and small correlations between change from baseline to EoM between UPDRS III and PDNMS scores (r=0.32, p<0.0001)
  • Small correlations between severity of early morning motor symptoms, as measured by UPDRS III, and nocturnal sleep disturbances, as measured by PDSS-2 total scores; Pearson correlation coefficients for UPDRS III and PDSS-2 total scores were 0.26 (p<0.0001) at baseline, 0.30 (p<0.0001) at EoM, and 0.36 (p<0.0001) for change from baseline to EoM.

  • Rotigotine provided long-term efficacy and tolerability

    Results from an open-label extension of a 6 month, Phase III, randomized, double-blind, placebo- and ropinirole-controlled trial (mean total duration 45+23 months) showed that rotigotine was generally well tolerated and that UPDRS motor and daily activity scores (UPDRS II+III) remained improved, compared to baseline, for over 4 years of treatment. This open label study enrolled 380 patients.

    Rotigotine plasma levels remained stable following transdermal patch removal and new patch application

    Mean trough plasma concentrations of rotigotine generally remained stable throughout a 4-month investigation of the effects of daily patch replacement on rotigotine plasma concentrations in 56 patients with advanced Parkinson's disease, taking part in a large multinational trial.

    About Neupro® in Europe

    Neupro® (rotigotine) is approved in the European Union for the treatment of the signs and symptoms of early-stage idiopathic Parkinson's disease, as monotherapy (i.e. without levodopa) or in combination with levodopa, i.e. over the course of the disease, through to late stages when the effect of levodopa wears off or becomes inconsistent and fluctuations of the therapeutic effe
    '/>"/>

    SOURCE UCB
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6

    Related medicine technology :

    1. Public Forum to Discuss Addiction as a Treatable Disease and Highlight National Alcohol and Drug Addiction Recovery Month
    2. Life Recovery Systems Receives European CE Mark Approval for Its ThermoSuit(R) System
    3. International Expert Group Initiates Largest Multi-center Phase III Trial to Evaluate NeuroAid(TM) in Stroke Recovery
    4. Sugammadex Trials Demonstrate Rapid Recovery from Profound Neuromuscular Blockade During General Anesthesia
    5. Surgex(TM) Becomes the First and Only BSCG (Banned Substance Control Group) Certified Product Which is Clinically Proven Effective in Sports Recovery and Performance
    6. Life Recovery Systems Receives NIH Grant to Study Expanded Use of Its ThermoSuit System
    7. Portable CT Increases Chance of Stroke Survival and Recovery
    8. Statins Lower Stroke Severity, Improve Recovery
    9. Sequella Receives American Recovery and Reinvestment Funding Through the NIH
    10. Reportlinker Adds Global Medical Devices Industry Outlook to 2010: Marketing And Sales Strategies And The Impact of Recession And Recovery
    11. Reportlinker Adds Global Drug Manufacturing Industry Outlook to 2010: Marketing and Sales Strategies and the Impact of Recession and Recovery
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:9/18/2014)... YORK , Sept. 18, 2014 This BCC Research ... share of major players, market growth and size, and opportunities ... trends and revenue through 2018. Patent analysis in the report ... as the U.S., Europe and ... to: - Define and discuss the global medical device technologies ...
    (Date:9/18/2014)... and LONDON , Sept. ... for biopharmaceutical companies. Competition for innovation, increasing clinical ... keep up with the fast-changing environment are important ... clinical trials, and clinical trial costs continue to ... recruitment. Studies conducted by industry think ...
    (Date:9/18/2014)... , Sept. 18, 2014  Iliad Neurosciences, Inc., ... to diagnosing and treating Autism Spectrum Disorders (ASD) announced ... Agreement with The Research Foundation for The State University ... will provide a new biomarker to identify an abnormality ... to ASD. This biomarker is expected to be available ...
    Breaking Medicine Technology:Medical Devices: Technologies and Global Markets 2Medical Devices: Technologies and Global Markets 3Medical Devices: Technologies and Global Markets 4Patient Recruitment in Asia Biotech and Pharma Companies 2Patient Recruitment in Asia Biotech and Pharma Companies 3Iliad Neurosciences, Inc. enters into an Exclusive License Agreement with The Research Foundation for The State University of New York 2Iliad Neurosciences, Inc. enters into an Exclusive License Agreement with The Research Foundation for The State University of New York 3
    ... PRA International, a leading Clinical Research Organization, will exhibit our ... (ESC) annual conference in Stockholm, Sweden from 28 ... booth C18:62, attendees can schedule meetings with our leading expert ... Head of Scientific Affairs at PRA, to learn how PRA ...
    ... 23 CVS/pharmacy, Boundless Playgrounds, and Pepsi are ... work together to provide all children with the ... environment.  The partnership is part of the Pepsi ... big and small, that can refresh the world. ...
    Cached Medicine Technology:PRA International to Exhibit at ESC's Annual Conference 2CVS/pharmacy and Boundless Playgrounds Join the Pepsi Refresh Challenge to Support Children of All Abilities 2CVS/pharmacy and Boundless Playgrounds Join the Pepsi Refresh Challenge to Support Children of All Abilities 3CVS/pharmacy and Boundless Playgrounds Join the Pepsi Refresh Challenge to Support Children of All Abilities 4
    (Date:9/19/2014)... (PRWEB) September 19, 2014 There are thousands ... for companionship and intimacy, and there are thousands of younger ... experienced, mature woman. SeekingCougar.com now provides the world's ... dating website caters to older women, and the younger men ... and convenient way for these people to meet each other ...
    (Date:9/18/2014)... 19, 2014 When Mary Ann Thompson and Mathieu ... who live in Bali, Indonesia with their son, Isaac, said there ... two met at Mercy College in 2001 when Thompson was an ... was a graduate student at the time, was French and so ... and migrated to the United States when she was 7 years ...
    (Date:9/18/2014)... Toronto, ON (PRWEB) September 18, 2014 ... Facial Plastic Surgeon with the American Academy of Facial ... University of Toronto in the Division of Facial Plastic ... his work in facial plastic surgery. , Dr. ... and foremost, he will be presenting on injection techniques ...
    (Date:9/18/2014)... (HealthDay News) -- Rising temperatures in the Atlantic Ocean ... shallow waters that are becoming warmer, an expansion that ... report. A study of 40 species along the ... by the invasive and poisonous lionfish, according to researchers ... the University of North Carolina-Wilmington, who published their findings ...
    (Date:9/18/2014)... It’s been just a few short weeks ... bunion splint to website visitors, but already the response has ... absolutely delighted. It is perfect and I find it sooo ... THANK YOU FOR LISTENING!!!" Another user compared the original ... used to slip to the end of my toe. Now ...
    Breaking Medicine News(10 mins):Health News:Dating Site "SeekingCougar.com" Now Offering Tips for Younger Men Seeking Older Women 2Health News:For The First Time in Over a Decade Mercy College Alumni Marry at College 2Health News:Dr. David A. F. Ellis Has Been Invited to Speak at a Conference of the American Academy of Facial Plastic and Reconstructive Surgery in Orlando, Florida 2Health News:Rising Atlantic Ocean Temperatures Could Pose Threat to Reefs 2Health News:Feedback for the New Bunion Bootie Design Feedback is Already Pouring In, and Bunion Sufferers Love It 2Health News:Feedback for the New Bunion Bootie Design Feedback is Already Pouring In, and Bunion Sufferers Love It 3
    ... WEDNESDAY, March 9 (HealthDay News) -- A newly identified toxin ... treat pain and disease in humans, scientists report. Spider ... control the flow of ions across cell membranes and play ... diseases. In their research on the venom of the ...
    ... 9 (HealthDay News) -- What difference does it make if ... millennia? A lot, as it turns out. Losing a few ... differently than those of other mammals. It may also be the ... some other animals, including chimpanzees and mice. It appears that ...
    ... polite act shows respect. But a new study of a ... a more practical, though unconscious, shared motivation: to reduce the ... and David A. Rosenbaum of Pennsylvania State University, is the ... altruism and motor control. It is to be published in ...
    ... clear and watery substance that bathes the brain and ... previously realized. Howard Hughes Medical Institute investigator Christopher ... Zappaterra, and their colleagues have discovered that cerebrospinal fluid ... dramatically with age. In the lab, CSF by itself ...
    ... News) -- Certain types of medical errors are 46 ... than bottom-ranked hospitals, according to a new study. ... 2007 to 2009 and focused on 13 patient safety ... foreign objects left in the body after procedures and ...
    ... 9, 2011) University of Minnesota researchers are using salmonella ... of U.S. residents each year to do what was ... Center researchers believe salmonella may be a valuable tool in ... such as the liver, spleen, and colon since that,s ...
    Cached Medicine News:Health News:Lost DNA May Have Made Us More Human 2Health News:More reasons to be nice: It's less work for everyone 2Health News:Cerebral spinal fluid guides stem cell development in the brain 2Health News:Cerebral spinal fluid guides stem cell development in the brain 3Health News:Hospital Safety Varies Widely Nationwide: Report 2Health News:U of M researchers using salmonella to fight cancer 2
    ... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
    ... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
    ... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
    ... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
    Medicine Products: