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R-Tech Ueno Completes Phase 2a Clinical Study of RK-023 to Treat Androgenetic Alopecia
Date:1/24/2011

ima, MD, PhD, provided the following comments: "RK-023 has been developed as an anti-aging or a lifestyle drug that is one of the areas on research and development in R-Tech Ueno. I am very pleased to obtain the favorable results in safety assessment and in efficacy of global photo assessment. It is estimated that the global market size of drugs for androgenetic alopecia is approximately one billion US dollars. RK-023 is an important drug of our pipelines to develop our business. For the future we will facilitate this project to obtain approval more quickly with a view to the possibility of tie-up with domestic and foreign partners. RK-023 will improve the quality of life (QOL) for androgenetic alopecia patients."

Note 1) Androgenetic alopecia, which is male-pattern alopecia, is a gradually progressive hair-thinning and alopecic disease with replacement of thick long hair by thin, short and soft hair without hair regeneration localized in the parietal to the frontal region under the effect of androgenic hormone after puberty, finally leading to atrophy in the hair follicles and reduction in the number of hair. About 12 million males are affected in Japan.

Note 2) Double-blind is a study method usually on human subjects in an attempt to eliminate subjective bias on the part of both experimental subjects and experimenters.

Note 3) Study drug without medical agent

Note 4) Phototrichogram is a noninvasive technique that analyzes hair density, hair diameter and a hair growth rate. A magnified photograph on a scalp hair cut area is analyzed.

Note 5) Anagen hair is defined as hair with a growth rate of 0.2 mm or more per day through phototrichogram. Anagen is the phase during which hair grows. Decrease of an anagen hair rate represents the progression of androgenetic alopecia.

About R-Tech Ueno, Ltd.

R-Tech Ueno is a bio venture company established in September 1989 for the purpose of R&D and marketing of drugs. Under
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SOURCE R-Tech Ueno, Ltd.
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