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R&D Trends: Depression - Clinical attrition driven by mature market conditions
Date:3/22/2012

NEW YORK, March 22, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

 

R&D Trends: Depression – Clinical attrition driven by mature market conditions

http://www.reportlinker.com/p0799259/RD-Trends-Depression-–-Clinical-attrition-driven-by-mature-market-conditions.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Pathology

 

Several drugs have progressed through the pipeline for depression in recent years, including Pristiq (desvenlafaxine; Pfizer), Oleptro (trazodone extended release; Labopharm), and Viibryd (Forest) in the US, and Valdoxan (agomelatine; Servier/Novartis) in the EU. Despite the heightened competition within the marketplace, an abundance of drugs remain in the pipeline.Understand key dynamics in the R&D pipeline for new depression therapies Benchmark novel and existing therapies using the target product profile identified by Datamonitor Support R&D decision making by evaluating antidepressant clinical trial designs that have set a precedent Evaluate the most promising new pharmacological targets in early-stage development Access Datamonitor's prediction of how the treatment landscape may change in the next 20 years There are 46 separate programs across all stages of clinical development for depression, down from 66 in 2007 with a notably high attrition of early-stage projects. Reasons for this include promising new targets failing to yield an effective antidepressant, and big players such as GlaxoSmithKline switching its research focus.Although depleted, the early-stage pipeline still has the potential to change current treatment algorithms, which are dominated by monoamine reuptake inhibitors. P
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