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Questcor Pharmaceuticals Responds to Questions From Investor Blog
Date:1/16/2012

ence flares and for whom steroid treatment has been ineffective or problematic., (for example, the patient did not fully respond to steroids, the patient had side effects to steroids that are problematic, the patient has poor venous access so that inserting an IV line is problematic, etc.).

4. On average, how often does an MS patient typically relapse? Has this time span widened with advances in the medications (including powerful new or treatments) used to control the underlying disease itself?

Questcor Response.  Based on publicly-available, peer-reviewed literature and information communicated by physicians, the Company believes that MS patients suffer a relapse on average every 12 to 24 months, but this can vary widely from patient to patient.  Questcor believes that the number of MS patients who suffer from flares and who are incomplete responders to steroids or who have problematic side effects from steroids, is materially higher than the current annualized run rate of Acthar prescriptions currently written for MS flares. Therefore, the Company believes that a significant opportunity may exist, through the continued education of physicians who treat MS patients, to increase the awareness of and potentially the usage of Acthar to treat MS flare patients. As has been previously publicly announced, the Company currently plans to expand the number of Acthar sales representatives promoting Acthar for MS flares during 2012.

The Company does not have information sufficient to comment on the impact of recently introduced medications, though we have noted the risk of the impact on the Company of these medications in our Form 10-K for 2010, as follows:

"Over the past several years disease modifying agents have been increasingly prescribed to treat the underlying disease state of MS, and the success of these treatments could reduce the overall incidence rate of acute exacerbations for MS including acute exacerbations of MS i
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SOURCE Questcor Pharmaceuticals, Inc.
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