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Quest Diagnostics Introduces ClariSure(TM) Test for Identifying Chromosome Abnormalities Associated With 85 Developmental Disorders in Children
Date:8/30/2007

re Test Applications

Nichols Institute also is developing additional ClariSure tests to identify chromosome abnormalities associated with hematological malignancies, such as Leukemia. The ClariSure test is able to detect abnormalities even if cell division has yet to occur, which may enable it to detect abnormalities that suggest the presence of cancer in a higher percentage of patients than is possible using conventional cytogenetic and FISH techniques. The company expects to begin to provide ClariSure assays for hematological malignancies to hospital physicians, including oncologists and hematologists, by the end of this year.

About Mental Retardation

Mental retardation and developmental delay are characterized by significant limitations in intellectual functioning and impaired conceptual and social development. Causes of mental retardation range from chromosome abnormalities to pre-natal environmental conditions. Array CGH techniques will detect chromosome abnormalities in as many as five percent to 17 percent of individuals with mental retardation.(3) With an accurate diagnosis, children are more likely to receive counseling, education and other support appropriate for their condition.

About Quest Diagnostics

Quest Diagnostics is the leading provider of diagnostic testing, information and services that patients and doctors need to make better healthcare decisions. The company offers the broadest access to diagnostic testing services through its national network of laboratories and patient service centers, and provides interpretive consultation through its extensive medical and scientific staff. Quest Diagnostics is a pioneer in developing innovative new diagnostic tests and advanced healthcare information technology solutions that help improve patient care. Additional company information is available at http://www.questdiagnostics.com.

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