Navigation Links
Quercegen Pharmaceuticals LLC Obtains FDA GRAS Notified Status for its QU995™ Quercetin with Purity Greater than 99.5%
Date:2/3/2011

SUDBURY, Mass., Feb. 3, 2011 /PRNewswire/ -- Quercegen Pharmaceuticals LLC, producer of plant-based nutrients for the pharmaceutical and nutraceutical industries and creator of Q-Force™, was notified that its QU995™, The World's Purest Quercetin™, received GRAS ("Generally Recognized As Safe") notified status on November 22, 2010 under U.S. Food and Drug Administration GRAS Inventory Number GRN 341. A copy of the comprehensive safety dossier submitted to the FDA by Quercegen can be found on the Agency's website. www.fda.gov/Food/FoodIngredientsPackaging/GenerallyRecognizedasSafeGRAS/GRASListings/ucm235935.htm

(Logo: http://photos.prnewswire.com/prnh/20110203/NE42268LOGO)

Quercetin is a natural polyphenolic antioxidant flavonoid found in many plants. It plays an important role in the inhibition of enzymes involved in free radical production and can potentially be used for the prevention and alleviation of conditions that cause oxidative stress. Quercetin is being studied for a wide range of health and performance benefits across the globe and is now serving as a functional ingredient to foods, beverages and dietary supplements.

"Achieving GRAS Status represents a major milestone for Quercegen Pharmaceuticals," said Quercegen CEO Gordon Brooks. "After many years of hard work and significant investment we are delighted to be able to offer products with our highly purified, food-grade Quercetin at levels of up to 500 milligrams per serving. We are grateful to our relentless science team as well as our commercial partners who helped us to achieve this."

Evolving from self-affirmed GRAS to gaining GRAS notified status from the FDA expands opportunities for QU995™ Quercetin to no longer be limited to dietary supplements, but can be used by food manufacturers worldwide. To be accepted in the mass food industry, a new food ingredient needs to be shown to be Generally Regarded As Safe (GRAS). In addition, the FDA will not consider an ingredient for a health claim (substantiated or qualified) if the ingredient has not been demonstrated to be GRAS.

After years of research and work in collaboration with Merck Natural Products, commercial partners and various United States government agencies, Quercegen is introducing its first branded product, Q-Force™ (www.qforce.com) to the U.S. and European markets. Together with DARPA (the U.S. Defense Advanced Research Projects Agency) and Nutravail Technologies, the Company developed Q-Force™ soft chews, which have been sold mainly to military personnel since 2007 and are now scheduled for a broader consumer rollout in 2011. Q-Force™ will be promoted towards active consumers seeking enhanced performance and overall health.  

"DARPA researchers have identified a very safe, natural antioxidant – called Quercetin – and developed it into a new form that is now available to the military and the general public. Among Quercetin's many potential benefits is illness prevention. In a randomized, placebo-controlled study, Quercetin helped prevent viral illnesses, like colds and flu, after physical exertion. Following a strenuous 3-day exercise routine, 50 percent of the control group became ill with colds and flu, whereas only five percent of the Quercetin supplemented group did. This important immune protective effect will help keep our warfighters healthy during training and deployment. Quercetin has been commercialized as RealFX Q-Plus™* soft chews, which are now available through several commercial vendors, as well as to all military personnel at a 50 percent discount."

--Dr. Tony Tether, Director, Defense Advanced Research Projects Agency Testimony Submitted to the Subcommittee on Terrorism, Unconventional Threats and Capabilities, House Armed Services Committee, United States House of Representatives, March 13, 2008.

(*RealFX Q-Plus™ was rebranded as Q-Force™ in 2010)

Quercetin has been the subject of over 7,000 research studies and the Company's QU995™ has been used in U.S. Department of Defense funded clinical trials in animals and humans since 2006.

"Quercetin exerts strong anti-oxidative, anti-inflammatory, anti-pathogenic, and immune regulatory effects in vitro and in animal-based studies. Epidemiological data indicates reduced rates of cardiovascular disease and various types of cancer in groups self-selecting diets high in Quercetin. Several recent supplementation studies in athletes have focused on Quercetin's potential influences as a countermeasure to post-exercise inflammation, oxidative stress, and immune dysfunction, in improving endurance performance, and in reducing illness rates following periods of physiological stress."

--David C. Nieman, DrPH, FACSM

Director, Human Performance Lab, North Carolina Research Campus

Professor, Appalachian State University

About Quercegen Pharmaceuticals

Quercegen Pharmaceuticals and its affiliates research, develop, manufacture, and market proprietary plant-derived pharmaceutical ingredients and nutraceutical products in the U.S. and abroad. One of the Company's affiliates, Quercegen Agronegocios, is the world's largest producer of Quercetin and operates a 3,600 hectare farm in northern Brazil. It processes plant materials into crude Rutin and Quercetin for purification at its plant in Sao Luiz and the resulting purified products are shipped around the world for inclusion in pharmaceuticals, dietary supplements and foodstuffs.

Quercegen together with Merck S.A. developed QU995™, the World's Purest Quercetin™, through a patented extraction and purification process. The Company has improved the bioavailability of the flavonoid Quercetin, through its patented QB3C™ formulation, which adds Vitamins B3 and C to its 99.5% pure Quercetin. This stabilizes Quercetin in water and boosts the natural bioavailability of Quercetin in circulating plasma, thereby significantly enhancing its therapeutic benefits.

Quercegen's QB3C™ formula is contained in its first product on the market, Q-Force™, which has been tested by soldiers serving in the U.S. Military. Q-Force soft chews are currently sold online at www.qforce.com.

More information can be found on the Company's web site www.quercegen.com


'/>"/>
SOURCE Quercegen Pharmaceuticals LLC
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
2. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
3. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
4. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
5. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
6. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
7. Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India
8. Nabi Biopharmaceuticals Announces Second Quarter 2007 Financial Results
9. Access Pharmaceuticals Provides Update on Clinical Development Plan of ProLindac
10. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
11. Acura Pharmaceuticals, Inc. Secures Financing to Fund Pivotal Phase III Clinical Trial for Lead Aversion(R) Technology Product Candidate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... Medivir AB (Nasdaq Stockholm: MVIR) ... Board of Directors that will be submitted to the ... representatives of the company,s three largest shareholders at the ... accepted a seat on the Nomination Committee, and the ... Nomination Committee was as follows:  ...
(Date:2/23/2017)... , Feb. 23, 2017  Genesis Healthcare Services has ... announcement was made by Bill Monast , President ... and Nathan Feltman , executives with Home ... Services, LLC. This acquisition helps Hospice ... of technology enabled durable medical equipment (DME) solutions for ...
(Date:2/23/2017)... and Markets has announced the addition of the "Menopause Drugs Price ... ... Analysis and Strategies - 2016, provides drug pricing data and benchmarks in ... What are the key drugs marketed for Menopause ... market? What are the unit prices and annual treatment ...
Breaking Medicine Technology:
(Date:2/23/2017)... ... February 23, 2017 , ... The Lymphoma Research Foundation (LRF) ... and serving the lymphoma community through a comprehensive series of education programs, outreach ... in Miami Beach to host its Swirl: Miami Wine Tasting Event on March ...
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... Los Angeles-based ... episodes of WE TV’s “Mama June: From Not to Hot,” which will begin airing ... “Mama” June Shannon, known to millions from the 2012 reality television series, “Here Comes ...
(Date:2/23/2017)... ... February 23, 2017 , ... ... for the National Institute for Health and Care Excellence (NICE) framework. ... the National Health Service (NHS) to search, order and purchase medical and healthcare-related ...
(Date:2/23/2017)... ... 23, 2017 , ... Pink Pig Publishing LLC announces the ... explore the world from different perspectives. By providing a place for people of ... increase empathy, and find greater happiness. , "Our approach to structuring content ...
(Date:2/23/2017)... ... February 23, 2017 , ... Healthcare Research & ... in the fight against cancer, has produced a seminal study that asked cancer ... release top-line findings in a webinar, Defining Compassionate Care Through the Voices of ...
Breaking Medicine News(10 mins):