Navigation Links
Queen's University Chooses Xceed's Ziplex(R) System for Translational Research
Date:9/15/2008

Study to validate gene signature designed to predict outcomes in follicular

lymphoma

WELLESLEY, Mass., Sept. 15 /PRNewswire/ -- Xceed Molecular, a pioneer in the development of cost-effective, easy-to-use gene-expression analysis systems, announced that Queen's University in Kingston, Ontario, Canada, is the latest high-profile institution to implement Xceed's Ziplex System as a critical tool to advance its translational research. Harriet Feilotter, Ph.D., FCCMG, of the University's Department of Pathology and Molecular Medicine, is the principal investigator of a study that will use the Ziplex System to validate her team's gene expression signature to predict the clinical outcomes in follicular lymphoma.

The most common form of non-Hodgkin lymphoma, accounting for one in four of all cases, follicular lymphoma is a slow-growing cancer that arises from B-lymphocytes, a type of white blood cell, and mainly affects older adults -- men and women in equal numbers. The mean age of diagnosis is between 50 and 60 years of age and because its symptoms are subtle in its earliest stages, the disease often can remain untreated for a long time before it becomes symptomatic. Although most patients have good outcomes and can live long and productive lives, in a substantial subset of patients, the disease can take a more aggressive course, resulting in shorter survival times.

"The work that Dr. Feilotter and her team at Queen's University have been doing to develop novel diagnostic and prognostic tools in cancer shows great promise, and we are excited to be a part of it," said Xceed President and CEO, David Deems. "Her follicular lymphoma research, which includes the use of both archival and fresh frozen tissues as sources of samples, has implications far beyond this particular research study. We look forward to a productive partnership."

Said Dr. Feilotter, "Our previous research identified a number of genes whose expression levels in primary follicular lymphoma were correlated with a five-year outcome. The Ziplex System will facilitate and streamline the critical next phase of our research to validate the signature. Currently there are no molecular diagnostic tools on the market that can predict which primary tumors will be aggressive. Having an easy way to accurately categorize an individual patient's risk will help clinicians determine the treatment plan that is most likely to result in a positive health outcome."

The Ziplex System is rapidly becoming the standard platform for the nation's leading institutions performing translational research. Xceed designed the Ziplex System with turnkey functionality and significant advances in automation, array format, fluidics, parallel sample processing, and analytics to minimize complexity, user interaction, and variability between users and sites.

About Xceed Molecular (http://www.XceedMolecular.com)

Xceed's vision is to advance molecular diagnostics by successfully translating novel multiplex tests into routine clinical practice and to create robust diagnostic solutions to improve disease outcomes. Our products comprise the Ziplex System for automated gene-expression analysis (available in the US and Canada for research use only), gene expression services, and pre-configured arrays -- Xpress Chips(TM). Xceed is also developing multiplexed genomic tests for the Ziplex platform, both internally and with strategic partners. Xceed's R&D and manufacturing are headquartered in Toronto, Ontario, with executive offices in Wellesley, Massachusetts.

About Queen's University (http://www.queensu.ca)

Established by Royal Charter of Queen Victoria in 1841, Queen's University was the earliest degree-granting institution in the united Province of Canada. Today, Queen's is one of Canada's leading universities, with an international reputation for scholarship, research, social purpose, spirit and diversity. The Department of Pathology and Molecular Medicine of Queen's University is affiliated with the University Hospitals Kingston. Its graduate program provides comprehensive training in basic and translational biomedical research and offers residency programs in anatomic, general, and hematopathology. Departmental research programs are focused on the understanding of the molecular pathogenesis of disease and the design and implementation of new therapeutic strategies.

Xceed Media Contact: Caroline Grossman -- 781.771.5579 --

caroline.grossman@gmail.com

Company Contact: Susan Josey -- 972-317-8948 --

sjosey@xceedmolecular.com


'/>"/>
SOURCE Xceed Molecular
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. deCODE and Radboud University Discover Common Variants in the Human Genome Conferring Risk of Bladder Cancer
2. The University of Nottingham in the British Midlands Announces Breakthrough in Parkinsons Disease Research
3. Boston University and The Center for Human Genetics, Inc. Announce Change in Testing Services
4. First U.S. Patient to Receive New Heart-Assist Device Doing Well After Surgery at University of Michigan
5. University of Rochester Researcher Named Millennium Pharmaceuticals Career Development Scholar of The Leukemia & Lymphoma Society
6. Terumo Heart Obtains IRB Approval from the University of Michigan to Initiate DuraHeart(TM) Left Ventricular Assist System U.S. Pivotal Trial
7. Orion Genomics Gains Exclusive Worldwide Rights to the IGF2 Gene for Colorectal Cancer Risk Testing Through Licensing Agreement With Johns Hopkins University
8. CellCyte Genetics Corporation Selects Washington University School of Medicine to Perform Study on CellCytes Glycoprotein Products in Heart Attack Disease Model
9. University of Miami Team Confirms Value of Monitoring Cell-Mediated Immunity Pre- and Post-Transplant in Management of Kidney Transplant Recipients
10. Kiadis Pharma Announces Collaboration With the Julius Maximilians University of Wurzburg, Germany
11. CellCyte Genetics Signs Collaborative Agreement With Northwestern Universitys Feinberg School of Medicine to Perform Disease Model Outcome Study of CellCytes CCG-TH30 Product Candidate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... 2016 Research and Markets has announced ... Diagnostic Tests" report to their offering. ... The World Market for Companion Diagnostics covers ... Market analysis in the report includes the following: ... Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/23/2016)... 2016  MedSource announced today that it has ... solution of choice.  This latest decision demonstrates MedSource,s ... their clients by offering a state-of-the-art electronic data ... nowEDC as the EDC platform of choice in ... "nowEDC has long been a preferred EDC platform ...
Breaking Medicine Technology:
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... ... 2016 , ... PawPaws brand pet supplements owned by Whole Health ... the health of felines. The formula is all-natural and is made from Chinese herbs ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
Breaking Medicine News(10 mins):