Navigation Links
Quatrx Pharmaceuticals Presents Results From Ophena(TM) (Ospemifene Tablets) Phase 3 Study Related to Treatment of Symptoms of Vulvovaginal Atrophy
Date:6/16/2008

Results presented at the 90th annual Endocrine Society meeting show significant improvements among women affected by moderate to severe vaginal

dryness and painful intercourse

ANN ARBOR, Mich, June 16 /PRNewswire/ -- QuatRx Pharmaceuticals today announced detailed primary endpoint results from a pivotal Phase 3 clinical trial of Ophena(TM) (ospemifene tablets) to treat postmenopausal women with symptoms of vulvovaginal atrophy, a common condition associated with menopause. The study successfully met all four co-primary endpoints. Women treated with Ophena(TM) at the 60 mg dose showed statistically significant improvements in vaginal dryness and dyspareunia (painful intercourse), as well as statistically significant improvement in the proportion of parabasal and superficial cells in the epithelium of vaginal walls and a decline in vaginal pH levels. Results of this Phase 3 clinical trial were presented today in a poster presentation at the 90th annual Endocrine Society meeting in San Francisco.

The decline in estrogen levels in women after menopause is associated with an increase in vaginal pH levels as well as a thinning of the vaginal wall, resulting in bothersome symptoms such as vaginal dryness and painful intercourse. In the Phase 3 Ophena(TM) clinical study, women were asked to identify their most bothersome symptom of vaginal atrophy. The co-primary endpoints were defined as the change from baseline to week 12 in the percentage of parabasal cells in the vaginal maturation index, the percentage of superficial cells in the vaginal maturation index, vaginal pH, and improvements in the most bothersome moderate to severe vulvovaginal atrophy symptom.

"Vaginal atrophy symptoms in postmenopausal women are usually progressive and, unlike hot flashes, do not resolve spontaneously. They can have a significant impact on a woman's quality of life. These Phase 3 clinical study results indicate that this new oral tablet ha
'/>"/>

SOURCE QuatRx Pharmaceuticals Company
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. QuatRx Pharmaceuticals Announces Presentation of Further Data from Ophena(TM) (Ospemifene) Phase 3 Study for Treatment of Symptoms of Vulvovaginal Atrophy
2. QuatRx Pharmaceuticals Announces Positive Phase 3 Results for Study of Ophena(TM) (ospemifene) to Treat Postmenopausal Vaginal Syndrome
3. QuatRx Completes Patient Enrollment in Phase 3 Study of Ophena(TM) in Women with Postmenopausal Vaginal Syndrome
4. Sunesis Pharmaceuticals Presents Data from Clinical Trials of Voreloxin (formerly SNS-595) in Patients with Acute Myeloid Leukemia at the 13th Congress of the European Hematology Association
5. European Enrollment Begins in Pivotal Phase 3 Trial of Novel Combination Medicine Developed by Cogentus Pharmaceuticals
6. Vion Pharmaceuticals Announces Presentation of Data of Cloretazine(R) (VNP40101M) in Elderly Patients with High-Risk Myelodysplastic Syndromes at the EHA Annual Meeting
7. Arena Pharmaceuticals Presented Positive Phase 2a Clinical Trial Results of APD125 for the Treatment of Insomnia at 22nd Annual Meeting of the Associated Professional Sleep Societies
8. Morria Biopharmaceuticals Plc Announces Regulatory Approval to Commence Phase II Clinical Study of MRX-4 in Allergic Rhinitis
9. Transcept Pharmaceuticals Announces Intent to Submit New Drug Application for Intermezzo(R) in Third Quarter 2008
10. Semafore Pharmaceuticals Reports Positive Interim Results from a Phase I Study of SF1126, a Targeted Pan-PI3K Inhibitor, in Patients with Advanced Solid Tumors
11. Sunesis Pharmaceuticals Focuses Resources on Development of Voreloxin (Formerly SNS-595)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... , July 11, 2014 The consumer ... evolving across industry sectors to better identify winning ... ways to engage with and understand consumers, as ... and make critical purchasing decisions. ... Practices, LLC, one area where organizations can observe ...
(Date:7/11/2014)... July 11, 2014  Kindred Hospital Houston Northwest, ... the opening of its new outpatient wound healing ... to people with chronic, hard to heal wounds. ... lead to amputation, lower leg wounds related to ... closure, and traumatic injury wounds which are complex ...
(Date:7/11/2014)... , July 11, 2014  Veran ... company, announced today the positive, cost-effective final ... innovative SPiNPerc™ procedure. The SPiNPerc endobronchial percutaneous ... a percutaneous approach to biopsy when a ... patients and physicians experience positive financial outcomes ...
Breaking Medicine Technology:New Technologies Transforming Consumer Marketing Research Playbook 2Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Veran Medical Publishes Lung Cancer Patient Management Study 2
...   Amcor Flexibles ... million in its Singen converting plant in ... of pharmaceutical packaging,and upgrades the classic converting ...      (Logo:  http://www.newscom.com/cgi-bin/prnh/20110630/465056  ) ...
... Va., June 29, 2011 The last ten years have ... Valley, Virginia. The former Pentagon employee, who survived the 9/11 ... debilitating neurological disorder. Medications controlled his tremor for ... Williams found it impossible to do anything with his dominant ...
Cached Medicine Technology:Amcor Invests €6.7 Million in the Extension of its Singen Converting Plant in Germany 2Video Features World's First Essential Tremor Patient Treated With Noninvasive MR-Guided Focused Ultrasound 2
(Date:7/14/2014)... (PRWEB) July 14, 2014 In ... carriers emphasized lower-cost narrow-network products, accountable care organizations ... chose coverage based on price, rather than on ... from seeking care from out-of-network providers. “Using ... Narrow Networks and Exchange Products,” the July ...
(Date:7/14/2014)... EnergyFirst, manufacturer of all-natural nutritional ... for its great products, thriving customer base, and ... its products as Jim’s Permalean Protein Powders and Jim’s ... EnergyFirst’s lineup of nutritional products. The Permalean brand will ... , Founded in 1999, Permalean’s products were designed to ...
(Date:7/14/2014)... 2014 Crystal Dental has recently ... The announcement has been made via LAD Solutions in in ... announcement has been made in order to draw in new ... Sacramento area. , Crystal Dental offers a variety of services ... offered by Crystal Dental include cosmetic dentistry procedures such as ...
(Date:7/13/2014)... St. Petersburg, FL (PRWEB) July 14, 2014 ... Fresh Citrus Scrub at Sublime Beauty®. Use coupon code ... Tuesday, July 15th. , "Everyone who tries the Fresh Citrus ... ® founder, Kathy Heshelow. "It is a perfect little cleanser ... too." , It has non-abrasive beads that help to exfoliate ...
(Date:7/13/2014)... Recently, iFitDress.com, one of the most famous dress ... of brown evening dresses for worldwide clients. ... discounted prices, up to 50% off. , All ... are carefully made according to most fashionable styles. In ... offers pretty accessories: wedding shoes, dancing shoes, sandals, boots ...
Breaking Medicine News(10 mins):Health News:Milliman, FAIR Health Executives to Discuss Data-Based Rate Setting for Out-of-Network Providers in Atlantic Information Services Webinar 2Health News:EnergyFirst Acquires Permalean - Manufacturer of All Natural Protein Bars and Powders 2Health News:EnergyFirst Acquires Permalean - Manufacturer of All Natural Protein Bars and Powders 3Health News:Crystal Dental Announces the Opening of New Office Location in Sacramento 2Health News:Discover the Favorite Sublime Beauty® Citrus Scrub: Special "Two-Day Only" Sale 2Health News:2014 Brown Evening Dresses Added To iFitDress.com 2
... tooth decay has been developed by BASF, a German company, and ... The company claims its// product can reduce the amount of harmful ... developed in collaboration with another German company OrganoBalance. ... mutans (bacteria involved in tooth decay) from adhering to the tooth. ...
... a team lead by Salim Yusuf and Koon Teo at the ... increases the risk of heart attack.// ,The study ... all forms, whether smoked or chewed first hand or second hand, ... among 27,000 people in 52 countries to calculate the risk of ...
... Health Survey for Punjab is bittersweet. While Punjab has ... retain the fertility// level at two children per woman, there ... Nearly 38% women and 30% men are obese, the ... CRRID in Punjab, studied nearly 3000 households. Gopal Krishan, director ...
... to throng the Mahim beach to drink sweet seawater ... people against drinking// the polluted water. ,Scientists ... the natural phenomenon of dilution. ,"Dilution is ... India during the southwest monsoon and occurs when rainwater ...
... study has found that childhood cancer survivors are at ... was made by Christopher Recklitis and colleagues// at the ... aged 28. All patients were adult survivors of childhood ... average of 18 years after their initial cancer diagnosis. ...
... a meeting of scientists in Australia, University of Oregon ... and cephalopods showed how brain regulation// is present even ... FMRFamide-related peptides are the two brain chemicals that enable ... in just seconds. ,In a paper that ...
Cached Medicine News:Health News:Maharashtra warns against Mahim's 'miracle' water 2Health News:Brain Regulation Present Even In Spineless Creatures 2Health News:Brain Regulation Present Even In Spineless Creatures 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: