Navigation Links
Quark Reports Progress of siRNA Clinical Programs; 300 Patients Dosed With Quark Pharmaceuticals' siRNA Drugs In Multiple Fully Enrolled Clinical Trials
Date:11/19/2009

ena. Quark's approach to therapeutic delivery allows targeting of tissues and organs including the eye, kidney, ear, lung, spinal cord and brain.

Quark's partner, Pfizer Inc, is advancing PF-4523655 (RTP801i-14), currently in two Phase 2 clinical studies in patients with diabetic macular edema (DME) and age-related macular degeneration (AMD). PF-4523655 is a synthetic, chemically modified siRNA designed to inhibit the expression of the gene RTP801 that was discovered by Quark through the gene discovery platform BiFAR(TM).

Quark's earlier-stage current clinical pipeline features QPI-1002, the first systemically administered siRNA drug in human clinical trials. QPI-1002 is evaluated for the prevention of acute kidney injury (AKI) following major cardiovascular surgery and the prophylaxis of delayed graft function after kidney transplantation. Enrollment was successfully completed recently in Phase I, respectively, Part A of a Phase 1/2 studies in these indications. For the structure of these products, Quark has licenses from Silence Therapeutics and from Alnylam Pharmaceuticals.

In the first quarter of 2010, Quark will begin a Phase 1/2 study of QPI-1007 as a neuroprotective agent for eye diseases. QPI-1007 is a siRNA drug candidate that utilizes a structure with freedom to operate in the siRNA intellectual property arena developed in collaboration with BioSpring GmbH. In addition, Quark has a broad pipeline of siRNA drug candidates that have arisen from Quark's research activities. The Company is committed to development of novel siRNA structures and expects to utilize these structures to develop additional RNAi drug candidates based on the Company's productive R&D engine.

Quark is headquartered in Fremont, California and operates research and development facilities in Boulder, Colorado and Ness-Ziona, Israel. Additional information is available at

SOURCE Quark Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Quark Pharmaceuticals to Present Data on its siRNA Therapeutic Programs in Kidney and Lung Diseases
2. Quark Pharmaceuticals Expands International Patent Protection for Compounds Targeting the RTP801 Gene
3. Quark Pharmaceuticals Presents at Asia TIDES Conference
4. Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function
5. Quark Pharmaceuticals Announces Publication of Study on Use of siRNA against Proprietary Target for Inhibiting Tumor Growth and Sensitization of Cancer Cells to Chemotherapy
6. Quark Pharmaceuticals Announces First RNAi Drug Candidate Having a Novel, Proprietary Structure Covered by Quark Intellectual Property
7. Silence Therapeutics to Receive $1.9m Milestone Payment as Pfizer and Quark Commence Phase II Trial
8. Quark Pharmaceuticals Announces First Patient Dosing by Pfizer in Phase II Trial of RNAi Therapy in Diabetic Macular Edema
9. Quark Pharmaceuticals, Inc. Announces First Systemic siRNA Dosing in Humans
10. Quark Pharmaceuticals Signs Collaboration Agreement With University of Michigan for Development of Proprietary SiRNA Compounds for Noise-Induced Hearing Loss
11. Quark Pharmaceuticals Appoints New Chief Medical Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... HILL, N.C. , May 24, 2013 /PRNewswire/ ... to the forefront of many organizations, priority list. ... and medical device sectors understand a strong ... current challenges in clinical development, market education ... effectively to create a vital bridge between an ...
(Date:5/24/2013)... FRANKLIN LAKES, N.J. , May 24, 2013  BD ... leading global medical technology company, announced today that it will ... Care Conference on Thursday, May 30, 2013, at 10:40 a.m. ... can be accessed from the BD corporate website at ... June 6, 2013.    About BD ...
(Date:5/24/2013)... 24, 2013 /PRNewswire-iReach/ -- Phoenix Houses of ... services organization, is hosting its tenth annual "Triumph For ... June 6, 2013.  More than 300 people are expected ... adolescent residential treatment centers, family therapy, and prevention programs ... accomplishments have positive influences on the health and welfare of ...
Breaking Medicine Technology:Building Medical Affairs Capabilities to Ensure Organizational Success across Key Operational Areas 2Phoenix House Honors Allergan Chairman David Pyott And Legendary Sports Agent And Humanitarian, Leigh Steinberg 2Phoenix House Honors Allergan Chairman David Pyott And Legendary Sports Agent And Humanitarian, Leigh Steinberg 3
... Smith & Nephew Orthopaedics (NYSE: SNN ) ... French biotechnology company Graftys. The deal gives Smith & ... bone void filler in the U.S., and potentially in ... committed to offering our surgeon customers innovative solutions which ...
... 24, 2011 HealthWarehouse.com, Inc. (OTC: HEWA) a leading ... results for the first quarter ended March 31, 2011. ... the Company,s quarterly net sales increased $1,031,003 to $2,284,552, ... This growth was driven by strength in its prescription ...
Cached Medicine Technology:Smith & Nephew Signs Distribution Agreement for Unique Injectable Bone Void Filler With Graftys 2Smith & Nephew Signs Distribution Agreement for Unique Injectable Bone Void Filler With Graftys 3HealthWarehouse.com Reports 82% Quarter-Over-Quarter Revenue Growth in the First Quarter 2011 2
(Date:5/24/2013)... KC and Monica Craichy, Founders of Living ... oldest sons, Kyle and Austin Craichy, will be kiteboarding with ... professional kiteboarders. , KC Craichy said he is excited to ... together such that virtually everyone who planned to be involved ... boarders will meet at Matheson Hammock Park and Beach in ...
(Date:5/24/2013)... With Memorial Day Weekend upon us, cookout season has officially ... to help prevent grill fires throughout the spring and summer. ... that gas grills led to an average of 7,100 home ... meanwhile, caused approximately 1,200 home fires per year during that ... the following tips from the NFPA to help protect your ...
(Date:5/24/2013)... The Mirena IUD lawyers at ... the FDA has received more than 59,229 complaints since 2004 ... intrauterine birth control device known as the Mirena IUD.* , ... by the women “included ‘expulsion,’ where the IUD came out ... according to an ABC News article. “Abdominal pain is also ...
(Date:5/24/2013)... May 24 (HealthDay News) -- New research suggests ... among people with insomnia. Every additional hour ... 72 percent drop in the likelihood of moderate ... from the University of Pennsylvania. "We ... between sleep duration and suicide risk," study author, ...
(Date:5/24/2013)... (PRWEB) May 24, 2013 E-Dentists.com has ... in partnership with JD Media Surge, a leading medical ... The dental SEO analysis service will focus on providing ... the search engines for their competitive keywords. The dental ... website and recommendations based on what their competitors are ...
Breaking Medicine News(10 mins):Health News:FreeRide836 Sponsor Living Fuel, The Leader in Superfood Nutrition, Announces Kiteboard Launch For This Sunday To Raise Money For Orphans In Africa 2Health News:FreeRide836 Sponsor Living Fuel, The Leader in Superfood Nutrition, Announces Kiteboard Launch For This Sunday To Raise Money For Orphans In Africa 3Health News:Don’t Get Burned: Five Grilling Tips from Amica Insurance 2Health News:Sufferers of Alleged Mirena IUD Side Effects Lodge More Than 59,000 Complaints With FDA, Rottenstein Law Group LLP Notes 2Health News:Sleep Duration Linked to Suicidal Thoughts in People With Insomnia 2Health News:Dental SEO Analysis Launched by E-Dentists.com in Partnership with JD Media Surge 2
... study may help put to rest fears that pregnancy ... receiving antiretroviral therapy. The study, published in the October ... now available online, revealed that pregnancy may, in fact, ... advent of highly active antiretroviral therapy (HAART), many women ...
... Segal Health Plan Cost,Trend Survey forecasts continued declines in ... medical trends. And, although a growing,number of health plans ... still significantly above general inflation. Key findings,include: ... for point-of-service (POS) medical ...
... District,Court for the District of Massachusetts has granted ... a class of people and entities that,purchased certain ... Health Benefits Fund v. First DataBank, Inc., No.,1:05-CV-11148-PBS ... Medi-Span, No.,07-cv-10988-PBS, concerning how the published price of ...
... of parents feel they play a significant role in ... at the University of Michigan C.S. Mott Childrens Hospital. ... issue of the Journal of Pediatrics, 86 percent of ... their hospitalized childs medical care. Researchers also found that ...
... Medicine (BUSM), Boston University School of Public Health ... Institute (NHLBI), have completed analyses of a genome-wide ... participants from the landmark Framingham Heart Study (FHS). ... potentially affect the risk for cardiovascular disease and ...
... researchers say , , WEDNESDAY, Sept. 19 (HealthDay News) ... knew little or nothing about peripheral arterial disease (PAD), ... legs that boosts heart risk. , "I don,t think ... PAD," said Dr. Timothy Murphy, a professor of diagnostic ...
Cached Medicine News:Health News:Pregnancy may slow -- not accelerate -- progression to AIDS 2Health News:Pregnancy may slow -- not accelerate -- progression to AIDS 3Health News:Segal Survey Predicts Declines in Trends for Fifth Consecutive Year 2Health News:Class Settlement Could Result in Considerable Savings for Certain Consumers of Prescription Pharmaceuticals 2Health News:Class Settlement Could Result in Considerable Savings for Certain Consumers of Prescription Pharmaceuticals 3Health News:Parents' participation in medical decisions linked to self-efficacy 2Health News:Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits 2Health News:Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits 3Health News:Few Americans Know of Leg Artery Danger 2Health News:Few Americans Know of Leg Artery Danger 3
The Skull Pins are inserted into the receptacles of the Skull Clamp and fixate the head during surgery....
It is designed for rigid skeletal fixation. These pins are constructed of stainless steel and can be removed for sterilization and reuse....
Mayfield radiolucent skull clamp....
... for general applications and are equipped with our ... i.e. rigid endoscopes, range between 1 mm and ... to a 120 retrospection, and image angles ranging ... Endoscopes with working lengths of 1.5 meters and ...
Medicine Products: