Navigation Links
Quark Pharmaceuticals Signs Collaboration Agreement With University of Michigan for Development of Proprietary SiRNA Compounds for Noise-Induced Hearing Loss
Date:9/24/2007

Quark Expands Hearing Loss Program With Novel SiRNA Approaches To Noise-

Induced Hearing Loss With Its First Drug Candidate, AHLI-11, For The Prevention Of Chemotherapy-Induced Hearing Loss In Late Pre-IND Stage

FREMONT, Calif., Sept. 24 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on discovering and developing novel RNA interference-based therapeutics, announced today that it has signed a collaboration agreement with the University of Michigan Kresge Hearing Research Institute (http://www.khri.med.umich.edu/) to begin pre-clinical studies of several new siRNA compounds for the treatment of acute hearing loss associated with acoustic (noise-induced) trauma through the inhibition of Quark's novel targets. These pre-clinical studies will be led by Professor Yehoash Raphael, Ph.D., Department of Otolaryngology at the University of Michigan.

These studies will target several different siRNA-based drug candidates that work by way of inhibition of Quark's proprietary target genes for the prevention and treatment of acoustic trauma-induced acute hearing loss. The multi-stage, animal model study will assess the ability to deliver these siRNA compounds to relevant cochlear cells in the inner ear. The efficacy of the selected siRNA compounds before and after acoustic trauma, the residence time of siRNA in the inner ear cells, and the duration of the therapeutic siRNA effect will also be primary focuses of the studies.

Daniel Zurr, CEO of Quark Pharmaceuticals, commented, "The establishment of this significant research collaboration with the University of Michigan enables us to expand our research program aimed at preventing and treating hearing loss. With an estimated 28 million Americans having some degree of hearing loss, this is a significant medical issue in the United States and throughout the world. Moreover, hearing loss is an u
'/>"/>

SOURCE Quark Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
2. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
5. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
6. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
7. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
8. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Keryx Biopharmaceuticals, Inc. Announces Positive Phase I and Phase II Data on KRX-0401 in Patients with Relapsed/Refractory Multiple Myeloma and Waldenstroms Macroglobulinemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)...  Xcelience, a contract development and manufacturing organization ... structured cash investment in Powdersize, a ... and powder size classification within the pharmaceutical industry.  ... simultaneously adding a complete set of particle size ... "As we continue to build our ...
(Date:7/31/2015)... 2015  Semler Scientific, Inc. (Nasdaq: SMLR ), ... healthcare insurers and physician groups, today reported financial results ... "In the second quarter of 2015, Semler ... of 54%, quarter over quarter revenue growth of 8%, ... of FloChec® units of 18%," said Doug Murphy-Chutorian, M.D., ...
(Date:7/31/2015)... CHICAGO , July 31, 2015 ... Composition Analyzers Market by Product (Bioimpedance Analyzers (BIA), Dual-Energy ... and Hydrostatic Weighing) - Global Analysis & Forecast to ... Market was pegged at $911.1 Million 2014 and is ... at a CAGR of 9.4% from 2014 to 2019. ...
Breaking Medicine Technology:Xcelience Makes Structured Cash Investment in Powdersize 2Xcelience Makes Structured Cash Investment in Powdersize 3Semler Reports Second Quarter 2015 Financial Results 2Semler Reports Second Quarter 2015 Financial Results 3Semler Reports Second Quarter 2015 Financial Results 4Semler Reports Second Quarter 2015 Financial Results 5Semler Reports Second Quarter 2015 Financial Results 6Body Composition Analyzers Market Worth $1,425.7 Million by 2019 2Body Composition Analyzers Market Worth $1,425.7 Million by 2019 3Body Composition Analyzers Market Worth $1,425.7 Million by 2019 4
... Link Platform: BNVI.PK) a pharmaceutical company focused on the ... women,s health and cancer, announced today that it will ... at 1:30 PM PST to discuss its 2011 financial ... (Logo:  http://photos.prnewswire.com/prnh/20111110/SF04662LOGO ) Interested ...
... INCLINE VILLAGE, Nev., Feb. 16, 2012  PDL BioPharma, Inc. ... the Company will release its fourth quarter and full ... 2011 on Thursday, February 23, 2012 after market close. ... that day at 4:30 p.m. Eastern Time to discuss ...
Cached Medicine Technology:PDL BioPharma to Announce Fourth Quarter and Full Year 2011 Financial Results on February 23, 2012 2
(Date:8/1/2015)... ... August 01, 2015 , ... ... (“GPP”) portfolio company has acquired Premier Physical Therapy & Wellness (“Premier”) — with ... of state-of-the-art clinics. , “Our acquisition of Premier Physical Therapy & Wellness solidifies ...
(Date:8/1/2015)... ... August 01, 2015 , ... On March 19, 2015 Phil Valentine – the Executive ... the Appalachian Trail by stepping off Springer Mountain and heading north. Since that ... 26th Phil reached Connecticut and was greeted by friends and family. He visited CCAR ...
(Date:7/31/2015)... ... ... Bowl 50 will emanate from Levi’s Stadium in Santa Clara, CA on Sunday, February ... In the two weeks that separate the conference championships and the Super Bowl, there is ... will mark the 50th time it has been held and the festivities will take place ...
(Date:7/31/2015)... Tenn. (PRWEB) , ... July 31, 2015 , ... The ... Robert Church Park in Downtown Memphis on October 3, 2015. The Ride to Fight ... focused on cancer research between Methodist Healthcare, The West Clinic and The University of ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... Coco Libre ... athletes, judges, media, and VIPs at the 2015 Vans US Open of Surfing, July ... water that can claim “no added sugar” on the market, is a natural choice ...
Breaking Medicine News(10 mins):Health News:Professional Physical Therapy Now Largest Outpatient Physical Therapy Provider in Northeast With Acquisition of Premier Physical Therapy & Wellness 2Health News:Connecticut Executive Hikes Appalachian Trail to Raise Awareness About Recovery. 2Health News:Cheap 2016 Super Bowl Tickets at Levi's Stadium: Ticket Down Slashes Ticket Prices on Super Bowl 50 Tickets in Santa Clara, CA at Levi's Stadium 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 2Health News:West Cancer Center Announces 2nd Annual Ride to Fight On 3Health News:Coco Libre Brings Eco-conscious Hydration to Vans US Open of Surfing 2
... ... tshirts featuring “text to” donation number on February 6th to heighten awareness about the ... ... Foundation, a nonprofit dedicated to providing health care services to underprivileged children in resource ...
... has joined mainstream for pain, anxiety and more, , ... be thought of as alternative therapy -- something that ... treatment. , No more. , U.S. soldiers returning from ... stress disorder. People suffering from chronic pain often find ...
... , , As Lower-Cost Methadone ... , Feb. 4 In a ... from 1999 -- 2009, the deaths involving methadone were found ... of all opioid prescriptions but is responsible for a third ...
... , ... the rigorous TRUSTe certification process and demonstrating its trustworthiness, Troubled Teens Wizard - a ... feature the TRUSTe Privacy Seal on its Web site. , ... Newport Beach, CA and San Francisco, CA ...
... ... ... Awaken Your Joy Empower Your Life, a ground-breaking new book by author Ted Karam, hit ... asked what Jumping On Water is all about? Karam explains, "As the title implies, it’s about ...
... ... San Diego, will be meeting with leaders from across the globe at one of the ... plastic surgeons and medical professionals from around the world to spend a few days presenting ... ...
Cached Medicine News:Health News:One5 Foundation Launches National Haitian Relief Campaign with TShirtAds 2Health News:One5 Foundation Launches National Haitian Relief Campaign with TShirtAds 3Health News:Biofeedback Now Seen as 'Regular' Medicine 2Health News:Biofeedback Now Seen as 'Regular' Medicine 3Health News:Methadone and Other Opioids Not Always Equivalent, Conversion Can Be Lethal 2Health News:Methadone and Other Opioids Not Always Equivalent, Conversion Can Be Lethal 3Health News:Methadone and Other Opioids Not Always Equivalent, Conversion Can Be Lethal 4Health News:Troubled Teens Wizard Earns Coveted Truste Certification 2Health News:Troubled Teens Wizard Earns Coveted Truste Certification 3Health News:Jumping On Water Hits Amazon Bestseller List 2Health News:Jumping On Water Hits Amazon Bestseller List 3Health News:Plastic Surgery Website Design Firm Rosemont Media Heads to Miami for the 44th Annual Baker Gordon Symposium 2Health News:Plastic Surgery Website Design Firm Rosemont Media Heads to Miami for the 44th Annual Baker Gordon Symposium 3
... The BeStent2, a laser-cut stent, is ... AVE stent systems for use after coronary ... in a therapy known as percutaneous transluminal ... incorporates a number of features designed to ...
... balloon catheter is a ... and is made of ... contained in the inner ... Radiopaque markings enhance the ...
For support, strength and control in your interventions, the RunWay Guide Catheter's large lumen and high-performance design represents a new era in guide catheters....
... developed over Guidants 20-year history, the VOYAGER ... for successful treatment outcomes. It combines a ... a lower profile shaft,more flexible markers, and ... cross tight and tortuous anatomy with even ...
Medicine Products: