Navigation Links
Quark Pharmaceuticals Signs Collaboration Agreement With University of Michigan for Development of Proprietary SiRNA Compounds for Noise-Induced Hearing Loss
Date:9/24/2007

Quark Expands Hearing Loss Program With Novel SiRNA Approaches To Noise-

Induced Hearing Loss With Its First Drug Candidate, AHLI-11, For The Prevention Of Chemotherapy-Induced Hearing Loss In Late Pre-IND Stage

FREMONT, Calif., Sept. 24 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company focused on discovering and developing novel RNA interference-based therapeutics, announced today that it has signed a collaboration agreement with the University of Michigan Kresge Hearing Research Institute (http://www.khri.med.umich.edu/) to begin pre-clinical studies of several new siRNA compounds for the treatment of acute hearing loss associated with acoustic (noise-induced) trauma through the inhibition of Quark's novel targets. These pre-clinical studies will be led by Professor Yehoash Raphael, Ph.D., Department of Otolaryngology at the University of Michigan.

These studies will target several different siRNA-based drug candidates that work by way of inhibition of Quark's proprietary target genes for the prevention and treatment of acoustic trauma-induced acute hearing loss. The multi-stage, animal model study will assess the ability to deliver these siRNA compounds to relevant cochlear cells in the inner ear. The efficacy of the selected siRNA compounds before and after acoustic trauma, the residence time of siRNA in the inner ear cells, and the duration of the therapeutic siRNA effect will also be primary focuses of the studies.

Daniel Zurr, CEO of Quark Pharmaceuticals, commented, "The establishment of this significant research collaboration with the University of Michigan enables us to expand our research program aimed at preventing and treating hearing loss. With an estimated 28 million Americans having some degree of hearing loss, this is a significant medical issue in the United States and throughout the world. Moreover, hearing loss is an u
'/>"/>

SOURCE Quark Pharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
2. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
5. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
6. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
7. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
8. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Keryx Biopharmaceuticals, Inc. Announces Positive Phase I and Phase II Data on KRX-0401 in Patients with Relapsed/Refractory Multiple Myeloma and Waldenstroms Macroglobulinemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... , July 24, 2014  Perrigo Company (NYSE: ... has received an AB therapeutic equivalent rating from the ... approved New Drug Application (NDA) for testosterone gel 1.0%. ... to [AbbVie,s] AndroGel 1% and can be substituted with ... clinical effect and safety profile as AndroGel 1% when ...
(Date:7/24/2014)... 24, 2014 Talyst, a market leader in ... Association of State Veterans Homes (NASVH) Summer Conference in ... of the NASVH is to ensure that each and ... term health care and respect which they have earned ... the InSite® Remote Dispensing System, Talyst can help State ...
(Date:7/24/2014)... Calif. , July 24, 2014  Lazarus ... development of novel interventional devices to facilitate removal ... States Patent and Trademark Office has issued a ... technology behind the company,s Lazarus Cover TM ... The Lazarus ReCover is a single-component stent-retriever (stentriever) ...
Breaking Medicine Technology:Perrigo Confirms AB Therapeutic Equivalent Rating From The FDA For Its Testosterone Gel 1.0% 2Perrigo Confirms AB Therapeutic Equivalent Rating From The FDA For Its Testosterone Gel 1.0% 3Talyst Exhibits at the National Association of State Veterans Homes Summer Conference 2Lazarus Effect Receives Notice of Allowance for New US Patent Covering Core Protection Technology 2
... Results Expected in November 2008, BOTHELL, Wash., Oct. ... today the completion of patient enrollment and dosing,for the ... safety and,efficacy of its formulation of 12-hour extended-release (ER) ... report top-line,results from this pivotal trial in November 2008. ...
... world,s most influential medical journal, the New England Journal,of ... company,s study,of the Diamyd(R) diabetes vaccine for type 1 ... article is now available on the journal,s web site,( ... 30. It presents the,results of the concluded Phase II ...
Cached Medicine Technology:SCOLR Pharma Announces Completion of Patient Enrollment and Dosing for Pivotal Clinical Trial Evaluating Extended Release Ibuprofen 2SCOLR Pharma Announces Completion of Patient Enrollment and Dosing for Pivotal Clinical Trial Evaluating Extended Release Ibuprofen 3Diamyd(R) Study Published in Prestigious New England Journal of Medicine 2Diamyd(R) Study Published in Prestigious New England Journal of Medicine 3Diamyd(R) Study Published in Prestigious New England Journal of Medicine 4
(Date:7/25/2014)... July 25, 2014 In an election year ... no surprise that Americans may not be sleeping well, and ... to a new poll conducted by US-Mattress . The ... across the country, “Which Political Party Do You Side With,” ... those registered as Independents tout a higher rate of good ...
(Date:7/25/2014)... NY (PRWEB) July 25, 2014 Ticket ... the Guinness International Champions Cup Match between Manchester City ... New York, one of the most iconic locations is Yankee ... Yankee Stadium, but it is quickly becoming a location that ... facility is home to the New York Yankees from Major ...
(Date:7/25/2014)... Oncology (ESMO), the leading pan-European association representing medical ... EU General Data Protection Regulation [1] could make ... to both doctors and cancer patients. , The ... and specific patient consent, meaning that researchers would ... is planned in order to consult their data ...
(Date:7/25/2014)... July 25, 2014 Yisrayl Hawkins, Pastor and ... article on his blog explaining why so many prayers are ... most. , In the article, Yisrayl gives many examples ... shares the results. For example, in one case, in the ... church grounds to pray for rain; ironically, they received a ...
(Date:7/25/2014)... 2014 iTanSmart is a patented iOS ... app provides a tailored approach to eliminating the guesswork ... and skin damage. In his review, Eaton had positive ... of iTanSmart. , Eaton begins his commentary ... ‘better organized’ and ‘great alternative’ to its related Android ...
Breaking Medicine News(10 mins):Health News:New Study Shows the Growing Number of Independent Voters Have a Greater Propensity for Sleeping Well vs. Democrats or Republicans 2Health News:New Study Shows the Growing Number of Independent Voters Have a Greater Propensity for Sleeping Well vs. Democrats or Republicans 3Health News:Manchester City vs. Liverpool FC Tickets Yankee Stadium: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match in NYC on July 30th 2Health News:Manchester City vs. Liverpool FC Tickets Yankee Stadium: Ticket Down Cuts Ticket Prices for Guinness International Champions Cup Match in NYC on July 30th 3Health News:Is Europe putting cancer research at risk? 2Health News:Yisrayl Hawkins Says Prayers for Rain Result in Violent Hail Because Prayers Are Not Being Heard in New Post 2Health News:Yisrayl Hawkins Says Prayers for Rain Result in Violent Hail Because Prayers Are Not Being Heard in New Post 3Health News:iTanSmart® Suntan App by UV Technologies, LLC Gets a ‘Big Thumbs Up’ from New York Times App Smart Columnist, Kit Eaton 2Health News:iTanSmart® Suntan App by UV Technologies, LLC Gets a ‘Big Thumbs Up’ from New York Times App Smart Columnist, Kit Eaton 3
... don,t protect against UVA rays, which can cause skin cancer ... of the most popular protections people use as the summer ... harmful ultraviolet rays. , Sunburns are not only painful, they ... cancer in the United States. , But, new research has ...
... WASHINGTON, July 12 Speaker Nancy Pelosi,issued the following statement ... "In his 70 years of medical practice, Dr. DeBakey had ... the globe by literally fixing, broken hearts. We honored ... Medal earlier this year., "Dr. DeBakey was one of ...
... , , SATURDAY, July 12 (HealthDay News) -- Summer is the ... is also the time for them to be most aware ... thunder roars, go indoors," Mary Ann Cooper, director of the ... Chicago, said in a prepared statement. "Decisions about lightning safety ...
... Emageon Inc.,(Nasdaq: EMAG ), a leader ... networks and imaging facilities,announced today that the Strategic ... Jefferies and Company as Lead Advisor and SunTrust,Robinson ... it evaluates all,strategic options available to the company., ...
... A,democratic process involving several SEIU local unions that began ... the best way to unite,long-term care workers in California ... their families and the clients they serve., "Today,s ... democratic,discussion to make sure that California long-term care workers ...
... million in cuts, WASHINGTON, July 11 Hundreds ... pay more out of pocket,for health care, while thousands ... approved this week by the U.S. Congress., The ... the,Medicare Advantage program over a five-year period, including cutting ...
Cached Medicine News:Health News:Are You Getting Burned by Your Sunscreen? 2Health News:Are You Getting Burned by Your Sunscreen? 3Health News:Summer Is Peak Time for Lightning Strikes 2Health News:Florida Seniors' Medicare Advantage Benefits at Risk 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: