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Quark Announces Dosing of the First Patient in Phase I Clinical Trial of its Ocular Neuroprotective Agent, QPI-1007
Date:3/1/2010

g was injected 2 weeks after IOP elevating operation.

About NAION

NAION is an acute ischemic disorder of the anterior optic nerve.  It is believed to be caused by acute ischemia of the optic nerve head resulting from insufficient arterial blood flow via the posterior ciliary artery.  Vision loss resulting from NAION is typically sudden, painless, and accompanied by pallid swelling of the optic disc.  In most cases patients have permanent severe visual deficits.  There is currently no approved treatment for NAION

About Quark Pharmaceuticals, Inc.

Quark Pharmaceuticals, Inc., is a leader in the discovery and development of novel RNAi-based drugs.  Quark has a fully integrated drug development platform spanning therapeutic target identification to drug development.  The Company's technology platform includes novel disease targets and siRNA structures and chemistry, providing Quark with freedom to operate in the siRNA intellectual property arena.  Quark's approach to therapeutic delivery allows targeting of tissues and organs including the eye, kidney, ear, lung, spinal cord and brain.


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