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QRxPharma Releases Additional Pivotal Phase 3 Combination Rule Study Data for MoxDuo(R)IR in Patients with Post-Surgical Pain
Date:5/4/2010

ith MoxDuo IR," added Holaday.  "Our Dual-Opioid™ formulation provides improved pain relief and greater tolerability as each drug component acts on different receptors.  This means we can enhance analgesia without significantly increasing side effects."

Among all groups, the most common moderate to severe adverse events were CNS (i.e. dizziness, somnolence, etc.) with an incidence range of 10% to 15%; gastrointestinal (i.e. nausea, emesis, etc.) with an incidence range of 15% to 30%; and dermatological (i.e. itchiness, skin rash, etc.) with an incidence range of 2% to 6%.  The percentage of patients in the MoxDuo IR group who reported moderate to severe vomiting was less than seen in previous studies and this was the only side effect that occurred more frequently with MoxDuo IR than its half-dose components.

"Having satisfied the combination rule requirement, we now turn our attention to the second and final MoxDuo IR registration trial, a study to evaluate the effectiveness of MoxDuo IR in patients following total knee replacement surgery, which was initiated in February 2010 and projected to complete dosing in Q3 2010," said Holaday.

Forward Looking Statements

This release contains forward-looking statements.  Forward-looking statements are statements that are not historical facts; they include statements about our beliefs and expectations.  Any statement in this release that states our intentions, beliefs, expectations or predictions (and the assumptions underlying them) is a forward-looking statement.  These statements are based on plans, estimates and projections as they are currently available to the management of QRxPharma.  Forward-looking statements therefore speak only as of the date they are made, and we undertake no obligation to update publicly any o
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