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QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen
Date:7/24/2014

HILDEN, Deutschland, und MARSEILLE, Frankreich, July 24, 2014 /PRNewswire/ --


  • Weltweite Exklusivlizenz der Universität Tokio ermöglicht QIAGEN die Entwicklung von Tests auf SF3B1-Mutationen, einschließlich von Next-Generation-Sequencing (NGS) Genpanels, für Blutkrebs 
  • Neuer Test weist Mutationen des SF3B1-Gens nach, die bei Patienten mit Knochenmarkserkrankungen (myelodysplastischen Syndromen) einen günstigen Krankheitsverlauf vermuten lassen 
  • QIAGEN sieht Potenzial für die Entwicklung von Begleitdiagnostika zur Steuerung von Therapien mit neuen Krebswirkstoffe, die auf das SF3B1-Gen abzielen 

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) gab heute den Erwerb der weltweiten Exklusivrechte an dem Biomarker SF3B1 von der Universität Tokio bekannt. SF3B1 spielt augenscheinlich eine wichtige Rolle bei der Prognose von Patienten mit myelodysplastischen Syndromen (MDS) - einer Gruppe hämatologischer Krebserkrankungen, bei der das Knochenmark zu wenige gesunde Blutzellen bildet. Mutationen dieses Gens, das ein wichtiger Bestandteil des Spliceosom-Zyklus ist, weisen bei Patienten auf einen günstigeren Krankheitsverlauf hin als bei einem nicht mutierten (Wildtyp-) Gen. Ein Test auf diese Genvarianten könnte daher wichtige Entscheidungshilfe im Rahmen personalisierter MDS-Therapien liefern.

"Dieser neuartige Biomarker erweitert QIAGENs marktführende Position im Bereich molekularer Tests für Blutkrebs um einen weiteren wichtigen Parameter. Unsere Tests und Panels decken die vollständige Palette dieser Krebserkrankungen ab, einschließlich auch der Knochenmarksstörung
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SOURCE QIAGEN N.V.
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