Navigation Links
QIAGEN and AstraZeneca Collaborate to Develop Liquid Biopsy-Based Companion Diagnostic to Advance EGFR Mutation Profiling in Lung Cancer Patients
Date:7/28/2014

HILDEN, Germany and LONDON, July 28, 2014 /PRNewswire/ --


  • Collaboration aims to create and commercialize companion diagnostic using genomic data from plasma samples to guide the use of IRESSA  for non-small cell lung cancer patients 
  • New blood test will build on QIAGEN's FDA-approved therascreen  EGFR test and is planned to run on Rotor-Gene Q, member of the QIAsymphony family of automated instruments 
  • Project enabled by AstraZeneca master framework agreement adds to QIAGEN's growing portfolio of liquid biopsy solutions, which  complement tissue-based testing solutions 

QIAGEN (NASDAQ: QGEN; Frankfurt, Prime Standard: QIA) today announced a collaboration agreement with AstraZeneca PLC (LSE, NYSE and OMX: AZN) for the co-development and commercialization of a liquid biopsy-based companion diagnostic to be paired with IRESSA, AstraZeneca's targeted therapy for non-small cell lung cancer (NSCLC). The project builds on a master framework agreement signed by both companies in 2013 and aims to develop and market a novel QIAGEN companion diagnostic that analyzes plasma samples to assess EGFR mutation status in NSCLC patients. The assay will be designed to guide the treatment of NSCLC patients with Astra Zeneca's oral monotherapy anti-cancer treatment when tumour tissue is not available. QIAGEN already offers the therascreen EGFR RGQ PCR Kit (therascreen EGFR test) as a tissue-based companion diagnostic for lung cancer patients, which was approved in the U.S. by the FDA in July 2013 and in China in May 2014.

The companies will collaborate to create a new companion diagnostic for IRESSA based on l
'/>"/>

SOURCE Qiagen
Copyright©2014 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen
2. QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline
3. QIAGEN and Exosome Diagnostics to Develop First-In-Class, Non-Invasive Diagnostics for Key Genetic Biomarkers in Lung and Other Cancers
4. Maverix Biomics Forms Strategic Co-Marketing Alliance with QIAGEN
5. QIAGEN Offers Clinical Labs Early Access to New Ingenuity Solution for Streamlined Interpretation of Patient Sequencing Data
6. Financial Results, Appointments, Earnings Conferences, and Partnerships - Research Report on New Oriental Education & Technology, Acacia Research, DeVry, Capella Education, and Qiagen NV
7. Exosome Diagnostics and QIAGEN Partner to Launch Comprehensive Line of Biofluid Nucleic Acid Kits to Address Limitations of Tissue Biopsy in Clinical Research Market
8. QIAGEN Significantly Expands its Offering of Assay Panels for Next-generation Sequencing (NGS) Complemented by Ingenuity Analysis and Interpretation Capabilities
9. QIAGEN Expands Pipeline of Promising New Biomarkers for Development of Personalized Healthcare Companion Diagnostics
10. QIAGEN Enters Into Broad Collaboration Agreement With Lilly for the Development and Commercialization of Companion Diagnostics
11. QIAGEN Kicks Off Next-Generation Sequencing Initiative With Launch of a Series of Consumable Products to Improve NGS Workflows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2015)... , March 2, 2015 ... the population with nearly 38,000 of those ... Staphylococcus Aureus), a highly contagious disease, infects ... deaths.  Each of these and more, not ... through casual contact with other infectious individuals, ...
(Date:3/2/2015)... -- Leading patient advocacy organization Fight Colorectal Cancer and ... One Million Strong campaign to spotlight colorectal ... funds for colorectal cancer education, research and prevention while ... living in the United States ... every day. Showing Strength for Colorectal Cancer ...
(Date:3/2/2015)... , Mar. 02, 2015 Research and Markets ... addition of the "Lopinavir - Comprehensive patent ... Imagine having your own team of ... button. Used by the world,s leading ... years, these searches are the benchmark in comprehensive, ...
Breaking Medicine Technology:Cleanint Rolls Out Cleanstethoscope and Cleanhands to Largest Medical Transportation Company in the Nation 2Cleanint Rolls Out Cleanstethoscope and Cleanhands to Largest Medical Transportation Company in the Nation 3Advocacy Group Fight Colorectal Cancer and Bayer HealthCare Join Forces for One Million Strong 2Advocacy Group Fight Colorectal Cancer and Bayer HealthCare Join Forces for One Million Strong 3Advocacy Group Fight Colorectal Cancer and Bayer HealthCare Join Forces for One Million Strong 4Advocacy Group Fight Colorectal Cancer and Bayer HealthCare Join Forces for One Million Strong 5Global Comprehensive Lopinavir Patent Search Online Portal 2015 2
... Sept. 17 Pharmasset, Inc.,(Nasdaq: VRUS ) management ... held from September 22-25, 2008 at the Grand Hyatt ... Officer,will provide an overview of the company on Wednesday, ... To access a live webcast of Mr. Price,s ...
... CT Colonography Trial Raise Questions for,Patients, OAK ... CT Colonography Trial, published in the September 18 ... improvements in the technology,s,ability to diagnose intermediate- to ... testing is not as effective in diagnosing small ...
Cached Medicine Technology:Pharmasset to Present at the UBS Global Life Sciences Conference on Wednesday, September 24th 2ASGE Encourages Patients to Speak to Their Doctor About Colorectal Cancer Screening Options 2ASGE Encourages Patients to Speak to Their Doctor About Colorectal Cancer Screening Options 3ASGE Encourages Patients to Speak to Their Doctor About Colorectal Cancer Screening Options 4ASGE Encourages Patients to Speak to Their Doctor About Colorectal Cancer Screening Options 5
(Date:3/2/2015)... March 02, 2015 Burns Engineering's ... calibration for Secondary Standard Platinum Resistance Thermometers (SSPRTs) ... business days or less . . . guaranteed. ... ® Accredited (Lab Code 200706-0), ISO 9001 and ... Temperature range is -196°C to 500°C, both ITS-90 ...
(Date:3/2/2015)... 2015 The minimally invasive surgical ... CAGR of 6.1% to reach $14,133.0 million by ... Factors such as advantages of minimally invasive surgeries ... to minimally invasive surgeries and increasing number of ... the global minimally invasive surgical instruments market. , ...
(Date:3/2/2015)... Four Seasons Resort Maui at Wailea, the ... this year, having officially opened its doors on March 2, ... honoring over 70 employees who started on Day 1 and ... approximately 400 original employees. The celebration will be a ... , This Four Seasons flagship resort, the first resort ...
(Date:3/2/2015)... March 02, 2015 The Alliance for ... safety expert Mark Chubb to serve as chief safety ... operations and training in Bangladesh and guide remediation efforts ... , “Mark will ensure that the Alliance continues to ... programs for Bangladesh garment workers,” said Alliance Independent Chair ...
(Date:3/2/2015)... Secura Consultants announced today the ... Protective Insurance Group of Birmingham, AL (First Protective). ... affiliated advisors to access the enhanced disability income ... delivers. , Secura Consultants, based in ... design and implementation of insured income protection programs. ...
Breaking Medicine News(10 mins):Health News:Burns Engineering Announces Quick-Turn Temperature Calibrations 2Health News:Minimally Invasive Surgical Instrument Market - Global Forecast to 2019 - New Report by MarketsandMarkets 2Health News:Celebrating Four Seasons Resort Maui’s 25th Anniversary 2Health News:Alliance for Bangladesh Worker Safety Names New Chief Safety Officer 2Health News:Secura Consultants and First Protective Insurance Group Announce Strategic Relationship 2
... leading journal Value in Health , the study ... cost effectiveness and fairness. The researchers concluded that ... have real benefits in terms of both economic efficiency ... other fatal diseases with similar age distributions. ...
... April 1, 2010 -- A resource for medical educators ... tools and resources, and advancing their careers in medical ... Physicians (ACP). "The Teaching Medicine series is the ... series editor, "This series summarizes the important literature of ...
... Care is undertaking an electronic medical record integration project ... is a multi-year, multi-entity corporate initiative to implement common ... in processes and workflows across the system. Currently in ... next four years, the way UMass Memorial collects, views, ...
... students, grades, study found , THURSDAY, April 1 (HealthDay News) ... more likely? , Perhaps, according to a study that found ... college students, grades. , Test-takers who saw the letter at the ... with a grade, scored significantly worse than those who saw an ...
... promise for women at increased risk , THURSDAY, April 1 (HealthDay ... greatly boosts the risk that a woman will develop breast cancer. ... risk of cancer in mice with that gene by deactivating another ... an 85 percent greater lifetime risk for developing breast cancer than ...
... hyperthyroidism should have it treated to reduce their ... -- Young adults who have an overactive thyroid face ... the condition, Taiwanese researchers report. , "This is a ... treatment to prevent these complications," Dr. Majaz Moonis, ...
Cached Medicine News:Health News:UMass Memorial health care develops fully integrated EMR 2Health News:Seeing Letter 'F' May Lower Test Scores 2Health News:Overactive Thyroid Linked to Stroke in Young Adults 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: