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QIAGEN Completes Second U.S.Submission for Companion Diagnostic to Guide Treatment Decisions in Colorectal Cancer
Date:8/5/2011

ighly effective in colorectal cancer patients who do not have these KRAS mutations, the QIAGEN assay enables physicians to predict which patients are likely to respond and to avoid the costs and harmful patient side effects of ineffective treatment. About 60 percent of all colorectal cancer patients have a non-mutated KRAS gene, while about 40 percent of patients show mutations that make their cancers unresponsive to this class of drugs. According to the National Cancer Institute, over 1 million patients in the U.S. were diagnosed with mCRC in 2010.

"QIAGEN's Personalized Healthcare franchise achieved a double milestone with these two separate U.S. submissions. These innovations show important progress in our strategy to accelerate QIAGEN's growth in 2012 and beyond. We are planning to validate the KRAS assay on our QIAsymphony RGQ platform, and we expect approvals of both PMAs in 2012," said Peer Schatz, Chief Executive Officer. "The  value of the information generated by our cutting-edge KRAS technology points to the significant potential of companion diagnostics, both to improve healthcare for patients and to save money. Experts have estimated that using KRAS testing in colorectal cancer patients could save healthcare systems more than $600 million in drug costs alone."

"QIAGEN has invested aggressively in Personalized Healthcare and is the global leader in partnering with pharmaceutical companies to create companion diagnostics. Our growing portfolio of companion diagnostics covers over 20 assays positioned as or targeted for use in personalized healthcare. In addition, QIAGEN is engaged in over 15 co-development partnerships with pharma. Our deep pipeline of regulated personalized healthcare assays includes an upcoming U.S. submission in 2012 for an EGFR biomarker test for use with an anticancer medicine for patients with non-small cell lung cancer," Mr. Schatz added. "Using molecular information to guide patients' treatments is changing
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SOURCE QIAGEN N.V.
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