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Pycnogenol® (French Maritime Pine Bark Extract) Shown To Improve Endothelial Function And Reduce Oxidative Stress In New Clinical Trial
Date:6/7/2012

HOBOKEN, N.J., June 7, 2012 /PRNewswire/ -- The body's first line of defense against coronary artery disease, the most common type of heart disease, are endothelial cells. These cells serve as the "traffic cop" for blood flow, directing blood to the appropriate area of the body such as the heart, brain, muscles or digestive system to support the body's actions. A study published in the January 2012 issue of European Heart Journal found that natural supplement Pycnogenol® (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree and natural solution for heart health, improves endothelial function in patients with stable coronary artery disease. 

"When coronary arteries are narrowed or blocked by plaque build-up, oxygen-rich blood cannot reach the heart muscle, often leading to a heart attack," says Dr. Frank Enseleit, the lead study researcher. "The results of this study show for the first time that Pycnogenol® significantly improves endothelial function and blood flow in patients with coronary heart disease."

The randomized, double-blind, placebo-controlled, crossover study was carried out at the Clinic for Cardiology at the University Hospital Zurich in Switzerland. The study investigated 23 patients with stable coronary artery disease, as documented by coronary angiography, nuclear imaging or positive stress test.

Patients were assigned to two groups. Patients in Group One received Pycnogenol® (200 mg/d) for eight weeks, then took placebo for another eight weeks. Group Two received the opposite sequence of placebo first, followed by eight weeks with Pycnogenol®. Before and after the eight weeks of treatment, blood samples were taken and the flow-mediated dilatation of the brachial arteries in the upper arm was established.


After eight weeks of treatment with Pycnogenol® the study found:

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SOURCE Horphag Research (USA) Inc.
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