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Pulmonary Drug Delivery Systems: Technologies and Global Markets
Date:12/19/2011

: Primary Respiratory … (Continued) 32

Asthma and Obesity 33

TABLE 5 ASTHMA AND BIOMARKERS 34

Monitoring of Asthma 35

TABLE 6 INHALED STEROIDS (ASTHMA INHALERS) 36

TABLE 7 SYSTEMIC STEROIDS FOR ASTHMA TREATMENT 37

Delivery Methods 37

Delivery Methods (Continued) 38

Delivery Methods (Continued) 39

Chronic Obstructive Pulmonary Disease (COPD) 40

What is COPD? 40

COPD and Causative Factors 41

TABLE 8 COPD AND LUNG DAMAGE 42

COPD and … (Continued) 43

Diagnosis of COPD 44

COPD and Treatment 45

Methods of Drug Delivery 46

METHODS OF DRUG DELIVERY 47

Aerosols 47

TABLE 9 COPD DRUGS ON THE MARKET 48

Formulations 49

INHALATION MARKET 49

Asthma Prevalence and Statistics 49

COPD and Incidence 50

Disease and Epidemiology 51

TABLE 10 INHALED DRUGS AND MARKET OPPORTUNITIES:

CURRENT MARKET FOR INHALED DRUGS (% MARKET SHARE) 52

CHAPTER FOUR: PULMONARY DRUG DELIVERY SYSTEM 53

BENEFITS OF PULMONARY DRUG DELIVERY SYSTEMS 53

INHALER DEVICES 53

TABLE 11 INHALER DEVICES 54

Pulmonary Drug Delivery Technologies 54

Technology Descriptions 54

Wide Array of Applications 54

TABLE 12 DRUGS AND THERAPEUTIC AGENTS ADMINISTERED BY

INHALATION 55

Types of Inhalation Devices 55

Inhalers 55

Metered-dose Inhalers 56

MDIs-How Does It Work? 56

History 57

MDIs and Drug Delivery 57

Advantages and Challenges for MDIs 58

MDIs and Corticosteroids 58

TABLE 13 BRAND NAME METERED DOSE INHALERS

(CORTICOSTEROIDS) 59

Bronchodilators 59

TABLE 14 BRAND NAME METERED DOSE INHALERS

(BRONCHODILATORS) 59

Combination Inhalers 59

Nonsteroidal Inhalers 60

Problems with MDI Use and Spacers 60

Problems with …(Continued) 61

Propellants and MDI Dev
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