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Published Data From e-HEALING Registry Demonstrate Good Clinical Outcomes With Low Incidence of Repeat Revascularization and Stent Thrombosis for OrbusNeich's Genous™ Stent
Date:2/22/2011

HONG KONG, Feb. 22, 2011 /PRNewswire/ -- OrbusNeich today announced that 12-month follow-up data from the e-HEALING (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth) registry published in the February issue of EuroIntervention demonstrated good clinical outcomes with low incidence of repeat revascularization and stent thrombosis (ST) for the company's Genous Stent.

Target vessel failure (TVF), defined as target vessel-related cardiac death or myocardial infarction (MI) and target vessel revascularization (TVR), was 8.4 percent at 12 months. The composite of death, MI or target lesion revascularization (TLR) occurred in 7.9 percent of the patients. TLR and ST were 5.7 percent and 1.1 percent, respectively.

"The good clinical outcomes for the Genous Stent in real-world use, especially the low incidence of stent thrombosis, demonstrate that the pro-healing approach of the Genous Stent is effective for a range of challenging patient groups," said Professor Sigmund Silber, M.D., Ph.D., of the Kardiologische Klinik Dr Muller, Munich, co-principal investigator and one of the lead authors of the publication. "As shown previously in several subset analyses of the e-HEALING registry, the Genous Stent produces exceptional outcomes in diabetic and elderly patients."

e-HEALING, a multi-center, worldwide prospective clinical registry conducted in 31 countries outside of the United States at 144 centers, included 4,939 patients with at least one lesion suitable for non-urgent percutaneous coronary intervention (PCI) and Genous Stent implantation. The mean age of the study population was 63 years, and 79 percent of patients were male. In addition, 25 percent of patients in the study cohort had diabetes mellitus, and 37 percent had a prior MI. On average, 1.3 lesions per patient were treated – 97.7 percent were de
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